FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3R)Ace-HD1
Open Close
General Information
Symbol
Df(3R)Ace-HD1
Species
D. melanogaster
Name
Deficiency (3R) Acetylcholinesterase
FlyBase ID
FBab0002488
Feature type
chromosomal_deletion
Also Known As
Df(3R)AceHD1, Df(3R)AceHD1
Computed Breakpoints include

87E3;87E5

Features within 87E3--87E5
Sequence coordinates
3R:13,255,722..13,257,275 [-] (Df(3R)Ace-HD1:bk1)
(Fournier et al., 1989)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
P-element activity
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(3)87Ec << bk1 << Ace << l(3)87Ee << bk2 << l(3)87Ef

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Reuter et al., 1987)

Proximal breakpoint between +49 and +50.5 kb; distal breakpoint between +72.5 and +77.8 kb (DNA walk of Bender, Spierer and Hogness, 1983, J. Mol. Biol. 168: 17-33).

Comments on Cytology

Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from inclusion of Ace (citation unavailable) Left limit of break 2 from polytene analysis (citation unavailable) Right limit of break 2 from non-inclusion of l(3)87Ef (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Su(var)3-7
(Schotta et al., 2002, Seum et al., 2000)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Suppresses the position effect variegation at the w locus caused by In(1)wm4 and suppresses the position effect variegation at the bw locus caused by In(2R)bwVDe2 and Byron. Also suppresses the position effect variegation of w seen in the P{wAR}41A insertion.

    (Sass and Henikoff, 1998)

    Suppresses the position effect variegation at the w locus caused by In(1)wm4 and Dp(3;Y)BL2, the position effect variegation at the bw locus caused by In(2R)bwVDe2 and Dp(?;2)bwD and the position effect variegation at the y locus caused by Dp(1;f)1187.

    (Cleard et al., 1997)
    NOT in combination with other aberrations

    Heterozygotes show a suppression of the position effect variegation seen in In(1)wm4. This phenotype is dominanted by the Y dependent enhancer of PEV effect.

    (Schotta et al., 2002)

    Heterozygotes show an increase in crossing over between kni and pp.

    (Westphal and Reuter, 2002)

    Suppresses the position effect variegation at the w locus seen in the insertion lines P{hsp26-pt-T}118E-10, P{hsp26-pt-T}39C-12 and P{hsp26-pt-T}Dyrk3118E-15, but has no effect on the position effect variegation at the w locus seen in the insertion line P{hsp26-pt-T}39C-5.

    (Cleard et al., 1997)

    Homozygotes are embryonic lethal and have no CNS-specific Ace enzyme.

    (Zador and Budai, 1994)

    does not fully remove Ace activity, but behaves as recessive Ace lethal.

    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Df(3R)Ace-HD1
    Df(3R)AceHD1
    (Seum et al., 2002, Delattre et al., 2000, Seum et al., 2000, Cleard et al., 1997, Zador and Budai, 1994, Fournier et al., 1989, Nagoshi and Gelbart, 1987)
    Df(3R)AceHD1
    (Schotta et al., 2002, Westphal and Reuter, 2002)
    Name Synonyms
    Deficiency (3R) Acetylcholinesterase
    Secondary FlyBase IDs
      References (16)