Aberration Dmel\Df(3R)Dl-BX12

General Information
Symbol	Dmel\Df(3R)Dl-BX12	Species	D. melanogaster
Name	Deficiency (3R) Delta	FlyBase ID	FBab0002534
Feature type	chromosomal_deletion
Also Known As	Df(3R)D1-BX12, Df(3R)DlBX12, Df(3R)DL^BX12

Computed Breakpoints include	91F1-91F2;92D3-92D6
Deleted segment	91F1--92D6
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Pauli et al., 1995, Rittenhouse and Berg, 1995, Harbecke and Lengyel, 1995, Salzberg et al., 1997, Jarecki et al., 1999)
Breakpoints	91F1-91F2;92D2-92D6 (Pauli et al., 1995) 91F1-91F2;92D3-92D6 (Harbecke and Lengyel, 1995, Rittenhouse and Berg, 1995, Salzberg et al., 1997) 91F;92D (Jarecki et al., 1999)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	pros << bk1 << cdi << bwk << bk2
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0080317) Left limit of break 2 from polytene analysis (FBrf0082073) Right limit of break 2 from polytene analysis (FBrf0080317)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	70 (Ejima et al., 2001) bnl (Spradling et al., 1999, Jarecki et al., 1999, BDGP Project Members, 1994-1999, Sutherland et al., 1996) bwk (Rittenhouse and Berg, 1995, Wilson et al., 1996) cdi (Spradling et al., 1999, BDGP Project Members, 1994-1999) cic (Goff et al., 2001) cry (Stanewsky et al., 1998) Dl (Szeged Stock Center, 1998-, Spradling et al., 1999, Alton et al., 1988, BDGP Project Members, 1994-1999, Harbecke and Lengyel, 1995, Pepple et al., 2007) l(3)91Fa (Alton et al., 1988) l(3)91Fb (Alton et al., 1988) l(3)91Fc (Alton et al., 1988) l(3)91Fe (Alton et al., 1988) l(3)91Ff (Alton et al., 1988) l(3)92Aa (Alton et al., 1988) l(3)03346 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)03675 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)05050 (BDGP Project Members, 1994-1999) l(3)05820 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)neo50 (BDGP Project Members, 1994-1999) l(3)S022930 (Szeged Stock Center, 1998-) l(3)S024639b (Szeged Stock Center, 1998-) l(3)S027302b (Szeged Stock Center, 1998-) l(3)S042622 (Szeged Stock Center, 1998-) l(3)S066317 (Szeged Stock Center, 1998-) l(3)S070103 (Szeged Stock Center, 1998-) l(3)S086112 (Szeged Stock Center, 1998-) l(3)S090302 (Szeged Stock Center, 1998-) l(3)S096901b (Szeged Stock Center, 1998-) l(3)S102315 (Szeged Stock Center, 1998-) l(3)S104115 (Szeged Stock Center, 1998-) nos (Spradling et al., 1999, BDGP Project Members, 1994-1999) S(CycE^JP)13S1 (Brumby et al., 2004) sqz (Spradling et al., 1999, Allan et al., 2003, BDGP Project Members, 1994-1999) trem (Page et al., 2007) Vha13 (Spradling et al., 1999, BDGP Project Members, 1994-1999) vib (Spradling et al., 1999, BDGP Project Members, 1994-1999, Giansanti et al., 2004, Giansanti et al., 2006, Szeged Stock Center, 1998-)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	fang (Myat et al., 2005) gatA (Szeged Stock Center, 1998-) gim (Myat et al., 2005) gloin (Myat et al., 2005) l(3)01344 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)06404 (BDGP Project Members, 1994-1999) l(3)10585 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)neo51 (BDGP Project Members, 1994-1999) l(3)neo53a (BDGP Project Members, 1994-1999) l(3)s1922 (BDGP Project Members, 1994-1999) mkf (Krishnan and Basole, 1999.4.2) pont (Szeged Stock Center, 1998-) pros (Salzberg et al., 1997)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The distal half of the salivary gland turns but the proximal half does not in embryos homozygous for Df(3R)Dl-BX12 by stage 14. (Jattani et al., 2009) Df(3R)Dl-BX12 embryos show defects in tracheal cell migration. (Myat et al., 2005) The Df(3R)Dl-BX12 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22. (Burnette et al., 1999) Heterozygous adults have significantly smaller phase delays than normal siblings in response to a 10 second pulse of blue light. Phase delays for heterozygotes are progressively larger in response to longer light pulses, but are not significantly different from control siblings. (Egan et al., 1999) The number of terminal tracheal branches (GB, LG and LH) are reduced by 30%-50% in heterozygous Df(3R)Dl-BX12 larvae. (Jarecki et al., 1999) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) Heterozygotes with Ser^Bd-3 are viable and exhibit a severe wing phenotype. (Hukriede and Fleming, 1997) Deficient embryos show an uninterpretable mutant midgut phenotype. (Bilder and Scott, 1995) Homozygous embryos are very abnormal compared to wild-type. Midgut primordia do not fuse and Malpighian tubules do not elongate normally. (Harbecke and Lengyel, 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 2 )
Bloomington	3012 Df(3R)Dl-BX12, ss¹ e⁴ ro¹/TM6B, Tb¹
Kyoto	106781 Df(3R)Dl-BX12, ss¹ e⁴ ro¹/TM6B, Tb¹
Notes on Origin
Discoverer	Muskavitch.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	Df(3)Dl Bx12 (Pueyo and Couso, 2011) Df(3R)D1-BX12 (Mason et al., 2004, Ashton et al., 2001, Cox et al., 2000, Spradling et al., 1999, Carrera et al., 1998, Halsell and Kiehart, 1998, Giansanti et al., 2006, Jattani et al., 2009) Df(3R)D1BX12 (Bilder and Scott, 1995) Df(3R)D1-X12 (Krishnan and Basole, 1999.4.2) Df(3R)DI-BX12 (Allan et al., 2003) Df(3R)DL^BX12 (Ejima et al., 2001) Df(3R)Dl^BX12 (Goff et al., 2001, Rittenhouse and Berg, 1995, Alton et al., 1988) Df(3R)Dl-Bx12 (Giansanti et al., 2004, Li et al., 2000, Harbecke and Lengyel, 1995, Dolezelova et al., 2007) Df(3R)DlBX12 (Shamloula et al., 2002, Firth et al., 2000, Jarecki et al., 1999, Sutherland et al., 1996, Pauli et al., 1995) Df(3R)Dl-BX12 (Page et al., 2007, Gatt and Glover, 2006, Ozdowski et al., 2009) Df(3R) Dl-BX12 (Pepple et al., 2007) DI-BX12 (Wilson et al., 1996)
Name Synonym	Deficiency (3R) Delta
Secondary FlyBase IDs

References ( 55 )

Generate a list of	All references relating to this aberration ( 55 )

List References by type	Research paper ( 49 ) Supplementary material ( 1 ) Personal communication to FlyBase ( 2 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Book ( 1 )
Recent research papers ( 1 )
	Pueyo and Couso, 2011, Dev. Biol. 355(2): 183--193 Tarsal-less peptides control Notch signalling through the Shavenbaby transcription factor. [FBrf0213970] Show all research papers ...