Aberration Dmel\Df(3R)GC14

General Information
Symbol	Dmel\Df(3R)GC14	Species	D. melanogaster
Name		FlyBase ID	FBab0002581
Feature type	chromosomal_deletion
Also Known As	tin^ΔGC14, tin^GC14

Computed Breakpoints include	93D6-93D7;93E1
Deleted segment	93D6--93E1
Map ( GBrowse )	Untitled Document Error No matching regions found.
Sequence coordinates	3R:17,209,495..17,212,798 [+] (Df(3R)GC14:bk1) (Azpiazu and Frasch, 1993)
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Mohler and Pardue, 1982, Georgiev and Kozycina, 1996)
Breakpoints	93D6-93D7;93D9-93D10 (Georgiev and Kozycina, 1996) [];[] (Mohler and Pardue, 1982)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(3)93Dd << bk1 << Hsrω << tin << bk2 << bap
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Walldorf et al., 1984)
Comments on Cytology
	Ref: FBrf0066905. (Georgiev and Kozycina, 1996) Not cytologically detectable. (Mohler and Pardue, 1984) Chromosome does not puff at 93D upon heat induction. (Mohler and Pardue, 1982) Left limit of break 1 from polytene analysis (FBrf0086415) Right limit of break 1 from inclusion of Hsrω (FBrf0040940) Left limit of break 2 from inclusion of tin (FBrf0058116) Right limit of break 2 from non-inclusion of bap (FBrf0058116)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Hsrω (Lakhotia and Tapadia, 1998, Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Df (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Dg (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Dh (Mohler and Pardue, 1984, Pardue et al., 1990) mod(mdg4) (Gerasimova et al., 1995, Georgiev and Kozycina, 1996) tin (Broihier et al., 1998, Moore et al., 1998, Bodmer, 1993, Azpiazu and Frasch, 1993, Reuter et al., 1993, Jagla et al., 1997, Clark et al., 2006)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	bap (Bodmer, 1993, Azpiazu and Frasch, 1993, Jagla et al., 1997) DNApol-ε (Akanksha et al., 2008) e (Mohler and Pardue, 1984) Hsrω (Lakhotia and Tapadia, 1998) InR (Mohler and Pardue, 1984, Jagla et al., 1997) l(3)93Ba (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Bb (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Ca (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Cb (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Cc (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Cd (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Da (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Db (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Dc (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Dd (Mohler and Pardue, 1984, Pardue et al., 1990) l(3)93Di (Mohler and Pardue, 1984) l(3)93Fa (Mohler and Pardue, 1984) l(3)93Fb (Mohler and Pardue, 1984) l(3)93Fc (Mohler and Pardue, 1984) lbe (Jagla et al., 1997) lbl (Jagla et al., 1997) Rab11 (Jankovics et al., 2001) slou (Jagla et al., 1997)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(3R)e-Gp4/Df(3R)GC14 lethal Df(3R)e-Gp4/Df(3R)GC14 die at all stages of development (Pardue et al., 1990)
NOT in combination with other aberrations	Few somatic gonadal precursors (SGPs) are specified and those that are specified fail to maintain their differentiated state. Germ cells are unable to transfer between germ layers in double mutant embryos with zfh1 (zfh1^65.34 or zfh1^75.26). Most germ cells adhere to the endoderm throughout embryogenesis, some scatter near the gut at late stages. (Broihier et al., 1998) The bridges of fat body that normally span the parasegments at stage 13 fail to form in Df(3R)GC14 embryos, and the fat body tissue remains in a state that morphologically resembles that seen at stage 12 in wild-type embryos. (Moore et al., 1998) The mod(mdg4)^ul product changes the phenotype of gypsy-induced mutations only in the presence of a functional su(Hw) protein. mod(mdg4)^ul exerts the same effect as Df(3R)GC14. (Georgiev and Kozycina, 1996)
Stocks ( 2 )
Bloomington	5797 Df(3R)GC14/TM6B, Tb⁺
Kyoto	108428 Df(3R)GC14/TM6B, Tb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	Df(3R)e-GC14 Df(3R)GC14 (Clark et al., 2006, Zaffran et al., 2006, Akanksha et al., 2008) Df(3R)tin^GC14 (Qian et al., 2008) Df(3R)tinGC14 (Qian and Bodmer, 2009) GC14 (Soltani-Bejnood et al., 2007) tin^Df(3R)GC14 (Jagla et al., 1998) tin^GC14 (DeFalco et al., 2003, Franch-Marro and Casanova, 2000, Park et al., 1998) tin^ΔGC14 (Marhold et al., 2003, Mukai et al., 1999, Moore et al., 1998, Moore et al., 1998)
Name Synonym
Secondary FlyBase IDs

References ( 36 )

Generate a list of	All references relating to this aberration ( 36 )

List References by type	Research paper ( 32 ) Review ( 2 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
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Recent reviews (0)
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Aberration Dmel\Df(3R)GC14

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