Aberration Dmel\Df(3R)Scx4

General Information
Symbol	Dmel\Df(3R)Scx4	Species	D. melanogaster
Name		FlyBase ID	FBab0002648
Feature type	chromosomal_deletion
Also Known As	Df(3R)Scx^w+Rx4, Df(3R)Scx⁴

Computed Breakpoints include	84B1;84D3-84D4
Deleted segment	84B1--84D4
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	In(3R)Scr^W (Scott et al., 1983) Scr^W (Hazelrigg and Kaufman, 1983)
Mutagen	X ray (Agnel et al., 1989, Scott et al., 1983, Hazelrigg and Kaufman, 1983, Pattatucci et al., 1991)
Class of aberration (relative to progenitor)	chromosomal_deletion (Agnel et al., 1989, Cavener et al., 1986, Hazelrigg and Kaufman, 1983, Spackman et al., 1994, Russell et al., 1996, Hutchens et al., 1997, Pattatucci et al., 1991, Baker et al., 1991)
Breakpoints	84B1-84B2;84D3-84D4 (Cavener et al., 1986) 84B3;84D1-84D2 (Hazelrigg and Kaufman, 1983, Baker et al., 1991, Pattatucci et al., 1991, Hutchens et al., 1997) 84B;84D3-84D4 (Agnel et al., 1989) [];84D1--84D2 (Spackman et al., 1994, Russell et al., 1996)
Causes alleles	Scr^Wrv4 (Hazelrigg and Kaufman, 1983, Southworth and Kennison, 2002)
Carries alleles
Transposon Insertions
Formalized genetic data	ftz << bk1 << Scr << rn << bk2 << Est-C
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Agnel et al., 1989)
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0044420) Right limit of break 1 from inclusion of Scr (FBrf0039462) Left limit of break 2 from inclusion of rn (FBrf0044420) Right limit of break 2 from polytene analysis (FBrf0044420)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Alh (Cavener et al., 1986, Kaufman et al., 1990) Antp (Scott et al., 1983, Hazelrigg and Kaufman, 1983, Agnel et al., 1989, Kaufman et al., 1990) gfzf (Cavener et al., 1986) Gld (Cavener et al., 1986) hat (Cavener et al., 1986) l(3)84Bb (Cavener et al., 1986, Kaufman et al., 1990) l(3)84Bc (Cavener et al., 1986) l(3)84Cb (Cavener et al., 1986) l(3)84Ce (Cavener et al., 1986) lap (Babcock et al., 2003) mab (Cavener et al., 1986, Kaufman et al., 1990) rn (Cavener et al., 1986, Agnel et al., 1989) rue (Cavener et al., 1986) sas (Cavener et al., 1986) Scr (Hazelrigg and Kaufman, 1983) ted (Cavener et al., 1986) αTub84B (Cavener et al., 1986, Hays et al., 1989, Kaufman et al., 1990, Hutchens et al., 1997)
Molecular Data
Completely deleted	Mlp84B (Clark et al., 2007)
Genes NOT Deleted / Disrupted
Complementation Data
	Antp (Pattatucci and Kaufman, 1991) bcd (Kaufman et al., 1990) Dfd (Hazelrigg and Kaufman, 1983, Kaufman et al., 1990) Est-9 (Spackman et al., 1994) ftz (Hazelrigg and Kaufman, 1983, Kaufman et al., 1990, Pattatucci and Kaufman, 1991) lab (Hazelrigg and Kaufman, 1983, Kaufman et al., 1990) pb (Hazelrigg and Kaufman, 1983, Kaufman et al., 1990) Scr (Scott et al., 1983, Kaufman et al., 1990, Pattatucci and Kaufman, 1991) Taf1 (Hazelrigg and Kaufman, 1983, Kaufman et al., 1990) twr (Hazelrigg and Kaufman, 1983, Kaufman et al., 1990) zen (Hazelrigg and Kaufman, 1983, Kaufman et al., 1990) α-Est5 (Cavener et al., 1986) α-Est7 (Spackman et al., 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments
	Df(3R)Scx4 deletes the "roe" (roughened eye) function of the rn locus. (Agnel et al., 1989) Affects both the "roe" (roughened eye) and "rn" (rotund) functions of the rn locus. (Cavener et al., 1986)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygotes are male fertile. (Hoyle et al., 2001) Hemizygous males are fertile but with reduced fecundity, the total testis tubulin pool is approximately half that of wild type. Spermatid nuclei are normally shaped but many spermatids are not properly aligned at the tip of the developing bundle. (Hutchens et al., 1997) Homozygous lethal. (Scott et al., 1983) homozygous lethal
Stocks ( 2 )
Bloomington	2009 Df(3R)Scx4, Scr^Wrv4 red¹ e¹/TM3, Sb¹
Kyoto	106626 Df(3R)Scx4, Scr^Wrv4 red¹ e¹/TM3, Sb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	Df(3R)Scx4 (Clark et al., 2007) Df(3R)Scx⁴ (Hoyle et al., 2001, Hutchens et al., 1997) Df(3R)Scx^w+Rx4 (Russell et al., 1996) Df(3R)Scx^w+RX4 (Spackman et al., 1994) Df(3R)Scx^W+RX4 (Hazelrigg and Kaufman, 1983, Scott et al., 1983, Brand and Campos-Ortega, 1990, Hays et al., 1989, Cavener et al., 1986, Agnel et al., 1989, ) Df(3R)Scx^w+X4 (Baker and Wolfner, 1988) Df(3R)Scx-W+R4 Df(α84B) (Hoyle et al., 2001) Scr^W+RX4 (Kaufman et al., 1990) Scx^W+R4 (Baker et al., 1991) Scx^W+RX4 (Kaufman et al., 1990)
Name Synonym
Secondary FlyBase IDs

References ( 21 )

Generate a list of	All references relating to this aberration ( 21 )

List References by type	Research paper ( 18 ) Review ( 1 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
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Recent reviews (0)
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