A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Aberration Dmel\Df(3R)T-32

General Information
SymbolDmel\Df(3R)T-32SpeciesD. melanogaster
NameFlyBase IDFBab0002655
Feature typechromosomal_deletion
Also Known AsDf(3R)TE32
Computed Breakpoints include 86E2-86E3;87C6-87C7
Deleted segment86D9--87C4 (Estimated cytology)
Map ( GBrowse ) GBrowse View Help Untitled Document detailed view
Sequence coordinates
3R:7,072,252..7,095,418 (Df(3R)T-32:bk1)
3R:8,486,218..8,498,999 (Df(3R)T-32:bk2)
Member of large scale dataset(s)
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Description
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FB2013_03
FB2013_02
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hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data Su(var)3-14 << bk1 << tho << l(3)87Cb << bk2 << l(3)87Cc
Genetic mapping information
Comments
hide Comments on Cytology
The left Df(3R)T-32 breakpoint lies within CG5214 or CG31386 or in the region between them, and lies in the range 3R:7072252..7095418 (R5) (predicted cytology: 86D9).
The right Df(3R)T-32 breakpoint lies within CG6225 or CG14395 or in the region between them, and lies in the range 3R:8486218..8498999 (R5) (predicted cytology: 87C3-87C4).
Left limit of break 1 from polytene analysis (FBrf0080317) Right limit of break 1 from inclusion of pros (FBrf0053403) Limits of break 2 from polytene analysis (FBrf0080317)
 
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DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
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Complementation Data
Completely deleted / disrupted
Molecular Data
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Complementation Data
Molecular Data
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Complementation Data
Molecular Data
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Complementation Data
Molecular Data
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In combination with other aberrations
NOT in combination with other aberrations
The distal half of the salivary gland turns but the proximal half does not in embryos homozygous for Df(3R)T-32 by stage 14.
The Df(3R)T-32 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).
Heterozygous males differ significantly from control males in their homo- and heterosexual courtship. These males do not discriminate between male and female target flies.
Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
Shows no maternal enhancement of dpphr4.
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
Deficient embryos show an uninterpretable mutant midgut phenotype.
Homozygous embryos are very abnormal compared to wild-type.
Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.
Suppresses In(1)wm4h variegation (Reuter, Gausz, Gyurkovics, Friede, Bang, Spierer, Hall and Spierer, 1987, Mol. Gen. Genet. 210: 429-36)
 
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Bloomington
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Discoverer
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hide Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym
Df(3R)Te32
Name Synonym
Secondary FlyBase IDs
hide References ( 40 )
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hide Recent research papers ( 1 )
Munoz-Soriano et al., 2012, J. Mol. Neurosci. 48(1): 136--143
Septin 4, the Drosophila Ortholog of Human CDCrel-1, Accumulates in parkin Mutant Brains and is Functionally Related to the Nedd4 E3 Ubiquitin Ligase. [FBrf0219099]