FlyBase Aberration Report: Dmel\Df(3R)Tl-P

General Information

Symbol

Df(3R)Tl-P

Species

D. melanogaster

Name

Deficiency (3R) Toll

FlyBase ID

FBab0002666

Feature type

chromosomal_deletion

Also Known As

Df(3R)T1-P, Df(3R)5B^RXP, Df(3R)TI-P, Df(3R)Tl^P

Computed Breakpoints include

97A;98A1-98A2

Features within 97A--98A2

Genomic Maps

JBrowse

Sequence coordinates

3R:26,059,954..26,078,012 (Df(3R)Tl-P:bk1)

(Yamamoto et al., 2009.2.25)

3R:27,388,608..27,480,200 (Df(3R)Tl-P:bk2)

(Yamamoto et al., 2009.2.25)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Tl²

(Anderson et al., 1985)

Mutagen

X ray

(Anderson et al., 1985)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Hukriede and Fleming, 1997, Cobb, 1996, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Castrillon et al., 1993, Anderson et al., 1985)

Breakpoints

97A;98A

(Anderson et al., 1985)

97A;98A1-98A2

(Hukriede and Fleming, 1997, Cobb, 1996, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Castrillon et al., 1993)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Indf << bk1 << spn-D << goul << bk2

Genetic mapping information

Comments

Comments on Cytology

The left Df(3R)Tl-P breakpoint lies within CG14551 or dys or in a region between these genes, and lies in the range 3R:21885676..21903734 (R5) (predicted cytology: 96F10-12).

(Yamamoto et al., 2009.2.25)

The right Df(3R)Tl-P breakpoint probably lies within side, CG13978 or Cyp6a18 or in a region between these genes, and lies in the range 3R:23214330..23305922 (R5) (predicted cytology: 97F8-98A2).

(Yamamoto et al., 2009.2.25)

Limits of break 1 from polytene analysis (FBrf0042050) Limits of break 2 from polytene analysis (FBrf0064394)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Ald1

(Miller et al., 2012)

ball

(Ivanovska et al., 2005)

goul

(Castrillon et al., 1993)

gro

(Cook and Carpenter, 2002)

His2Av

(Cook and Carpenter, 2002, Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(3)S100604

(Szeged Stock Center, 1998-)

Pdf

(Renn et al., 1999)

pll

(Tearle and Nusslein-Volhard, 1987)

Pri

(Jurgens and Weigel, 1988)

Rb97D

(Cook and Carpenter, 2002, Spradling et al., 1999, BDGP Project Members, 1994-1999)

(Cook and Carpenter, 2002, Jurgens and Weigel, 1988)

scrib

(Brumby et al., 2004, Thibault et al., 2004, Cook and Carpenter, 2002, Spradling et al., 1999, Szeged Stock Center, 1998-, BDGP Project Members, 1994-1999)

Ser

(Hukriede and Fleming, 1997)

side

(Sink et al., 2001)

small-potatoes

(Ghabrial et al., 2011)

spn-D

(Abdu et al., 2003, Gonzalez-Reyes et al., 1997)

(Cook and Carpenter, 2002, Cook, 2000.10.9, Anderson et al., 1985)

(Cook and Carpenter, 2002)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Fer2LCH

(BDGP Project Members, 1994-1999)

Indf

(Cobb, 1996)

l(3)02670

(BDGP Project Members, 1994-1999)

l(3)03077

(BDGP Project Members, 1994-1999)

l(3)03884

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(3)neo59

(BDGP Project Members, 1994-1999)

l(3)rK344

(Cook, 2000.10.9)

S(CycE^JP)1S3

(Brumby et al., 2004)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (177)

Related Comments

Phenotypic Data

In combination with other aberrations

Inferred to overlap with: Df(3R)Espl3.

(Cook and Carpenter, 2002)

No effect on In(1)w^m4h position-effect variegation.

(Wustmann et al., 1989)

NOT in combination with other aberrations

The Df(3R)Tl-P chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3R)Tl-P results in 3.7% X chromosome nondisjunction and 5.6% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Causes inviability or low viability in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Heterozygotes with Df(3R)Delta-BX6 are fully viable.

(Hukriede and Fleming, 1997)

Wild type nonanol phenotype; repulsion.

(Cobb, 1996)

Dominantly causes tergite defects in less than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Midgut development of mutant embryos is wild type.

(Bilder and Scott, 1995)

Homozygous embryos have smaller heads than normal.

(Harbecke and Lengyel, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

heterozygous females viable heterozygous females fertile

Stocks (3)

Bloomington

1910

Df(3R)Tl-P, e¹ ca¹/TM3, Ser¹

Kyoto

106725

Df(3R)Tl-P, e¹ ca¹/TM3, Ser¹

103311

Df(3R)Tl-P, e¹ ca¹ / TM3, y⁺ kni^ri-1 p^p vvl^sep Sb¹ Ubx^bx-34e e^s Ser¹

Notes on Origin

Discoverer

Anderson.

Revertant.

(Anderson et al., 1985)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (18)

Reported As

Symbol Synonym

Df(1)Tl-P

(Jackson and Berg, 1999)

Df(3R) Tl-P

(Fiehler and Wolff, 2008)

Df(3R)5B-RXP

(Gonzalez-Reyes et al., 1997)

Df(3R)5B^RXP

(Wustmann et al., 1989, Jurgens and Weigel, 1988, Jurgens et al., 1984)

Df(3R)9Q-RXP

(Tearle and Nusslein-Volhard, 1987)

Df(3R)T1-P

(Mason et al., 2004, Tsai et al., 2004, Abdu et al., 2003, Harris et al., 2003, Coyne et al., 1998, Halsell and Kiehart, 1998)

Df(3R)T1^P

(Brumby et al., 2004)

Df(3R)TI-P

(Miller et al., 2012, Carrera et al., 1998)

Df(3R)TL-P

(Duffy et al., 1996)

Df(3R)Tl-5BRXP

(Knibb et al., 1993)

Df(3R)Tl-P

(Ribot et al., 2022, Komori et al., 2018, Galindo et al., 2014, Ghabrial et al., 2011, McElwain et al., 2011, Yamamoto et al., 2009.2.25, Kucherenko et al., 2008, Martinek et al., 2008)

Df(3R)Tl5BRXP

Df(3R)Tl^5BRXP

(Sink et al., 2001)

Df(3R)Tl^P

(Kolsch et al., 2007)

Df(3R)Tl^p

(Seher et al., 2007)

Df1910

(Sink et al., 2001)

Tl^5BRXP

(Anderson et al., 1985)

Name Synonyms

Deficiency (3R) Toll

Secondary FlyBase IDs

FBab0027963
FBab0002477

References (62)

Report Sections