Aberration Dmel\Df(3R)XM3

General Information
Symbol	Dmel\Df(3R)XM3	Species	D. melanogaster
Name		FlyBase ID	FBab0002699
Feature type	chromosomal_deletion

Computed Breakpoints include	82A3-82A6;82B
Deleted segment	82A3--82B
Sequence coordinates
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << tub << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from inclusion of tub (FBrf0064499) Limits of break 2 from polytene analysis (citation unavailable)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	tub (Hecht and Anderson, 1993, Letsou et al., 1993, Gillespie and Wasserman, 1994, Belvin et al., 1995, Galindo et al., 1995)
Molecular Data
Completely deleted	CG11739 (Faivre-Sarrailh et al., 2004) Cont (Faivre-Sarrailh et al., 2004) tub (Faivre-Sarrailh et al., 2004)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 2 )
Bloomington	1655 Df(3R)XM3, ru¹ th¹ st¹ kni^ri-1 cu¹ p^p e¹/TM3, Sb¹
Kyoto	106434 Df(3R)XM3, ru¹ th¹ st¹ kni^ri-1 cu¹ p^p e¹/TM3, Sb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(3R)hkb^XM3 (Halfon and Keshishian, 1998, Misra et al., 1998, Grosshans et al., 1994, Hecht and Anderson, 1993) Df(3R)XM3 (Minidorff et al., 2007)
Name Synonym
Secondary FlyBase IDs

References ( 19 )
Research paper	Minidorff et al., 2007, Genetics 176(4): 2247--2263 A Gain-of-Function Screen for Genes That Influence Axon Guidance Identifies the NF-κB Protein Dorsal and Reveals a Requirement for the Kinase Pelle in Drosophila Photoreceptor Axon Targeting. [FBrf0202193] Faivre-Sarrailh et al., 2004, Development 131(20): 4931--4942 Drosophila contactin, a homolog of vertebrate contactin, is required for septate junction organization and paracellular barrier function. [FBrf0180155] Sun et al., 2004, EMBO J. 23(1): 100--110 Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning. [FBrf0167555] Towb et al., 2001, Development 128(23): 4729--4736 The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway. [FBrf0141492] Schmucker et al., 2000, Mech. Dev. 91(1-2): 189--196 The Drosophila gene abstrakt, required for visual system development, encodes a putative RNA helicase of the DEAD box protein family. [FBrf0127310] Xiao et al., 1999, Cell 99(5): 545--555 Three-dimensional structure of a complex between the death domains of Pelle and Tube. [FBrf0123247] Halfon and Keshishian, 1998, Dev. Biol. 199(1): 164--174 The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo. [FBrf0103273] Misra et al., 1998, Development 125(7): 1261--1267 Positive and negative regulation of easter, a member of the serine protease family that controls dorsal-ventral patterning in the Drosophila embryo. [FBrf0101959] Towb et al., 1998, Development 125(13): 2443--2450 Recruitment of tube and pelle to signaling sites at the surface of the Drosophila embryo. [FBrf0103055] Edwards et al., 1997, Development 124(19): 3855--3864 An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators. [FBrf0099196] Belvin et al., 1995, Genes Dev. 9(7): 783--793 Cactus protein degradation mediates Drosophila dorsal-ventral signaling. [FBrf0079887] Galindo et al., 1995, Development 121(7): 2209--2218 Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos. [FBrf0080037] Gillespie and Wasserman, 1994, Molec. Cell. Biol. 14(6): 3559--3568 dorsal, a Drosophila Rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll. [FBrf0073171] Grosshans et al., 1994, Nature 372(6506): 563--566 Activation of the kinase pelle by tube in the dorsoventral signal transduction pathway of Drosophila embryo. [FBrf0076994] Grossniklaus et al., 1994, Development 120(11): 3155--3171 Three maternal coordinate systems cooperate in the patterning of the Drosophila head. [FBrf0073235] Hecht and Anderson, 1993, Genetics 135(2): 405--417 Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo. [FBrf0064499] Letsou et al., 1993, EMBO J. 12(9): 3449--3458 Domain mapping of tube, a protein essential for dorsoventral patterning of the Drosophila embryo. [FBrf0064579] Letsou et al., 1991, Proc. Natl. Acad. Sci. USA 88: 810--814 Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity. [FBrf0055013]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]