A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(3R)by10

General Information
SymbolDmel\Df(3R)by10SpeciesD. melanogaster
NameDeficiency (3R) blisteryFlyBase IDFBab0002713
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data l(3)05430 << bk1 << sic << MtnA << bk2 << MED6
Sequence coordinates
Deleted segment85D8--85E13
Duplicated segment
Computed Breakpoints include 85D7--9;[] 85D8;85E10-85E13
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Kemphues et al., 1980)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Simon et al., 1991, Pauli et al., 1995, Duffy et al., 1996, Kemphues et al., 1983, Reuter et al., 1986, Bhadra and Birchler, 1996, Schnorr and Berg, 1996, Harbecke and Lengyel, 1995, Craig and Brink, 1996, Salzberg et al., 1997, Kemphues et al., 1980)
Breakpoints
85D7--9;[]
(Kemphues et al., 1980)
85D8-85D12;85E7-85F1
(Kemphues et al., 1983, Reuter et al., 1986, Pauli et al., 1995, Duffy et al., 1996, Bhadra and Birchler, 1996, Craig and Brink, 1996, Li et al., 1997, Salzberg et al., 1997)
85D8-85D11;85E10-85E13
(Simon et al., 1991, Schnorr and Berg, 1996)
85D8-85D12;84E7-84F1
(Harbecke and Lengyel, 1995)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
Left limit of break 1 from polytene analysis (FBrf0045055) Right limit of break 1 from inclusion of Aats-trp (FBrf0067338) Left limit of break 2 from inclusion of MtnA (FBrf0044456) Right limit of break 2 from polytene analysis (FBrf0053392)
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Aats-trp
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
pum
(BDGP Project Members, 1994-1999)
ps
(Seshaiah et al., 2001)
dmt
(Salzberg et al., 1994)
αTub85E
(Seshaiah et al., 2001)
hyd
(Mansfield et al., 1994, Seshaiah et al., 2001)
eca
(Bartoszewski et al., 2004)
Scm
(Jurgens, 1985, Tearle and Nusslein-Volhard, 1987, Harbecke and Lengyel, 1995, Seshaiah et al., 2001)
by
(Kemphues et al., 1980)
Ras85D
(Simon et al., 1991, Kolodkin et al., 1994, Begemann et al., 1995, Kramer et al., 1995, Schnorr and Berg, 1996, Fischer et al., 1997, Schnorr et al., 2001)
topi
(Perezgasga et al., 2004)
MtnA
(Maroni et al., 1986)
tws
(BDGP Project Members, 1994-1999)
knk
(Tearle and Nusslein-Volhard, 1987)
l(3)L4092
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
dc
(Craig and Brink, 1996)
l(3)85Ed
(Seshaiah et al., 2001)
l(3)85Ec
(Seshaiah et al., 2001)
sic
(Tearle and Nusslein-Volhard, 1987)
vacu
(Palladino et al., 2002)
l(3)85Eb
(Seshaiah et al., 2001)
l(3)85Dj
(Seshaiah et al., 2001)
l(3)85De
(Seshaiah et al., 2001)
hau
(Giesen, 2001.1.24)
l(3)85Da-2
(Seshaiah et al., 2001)
l(3)85Db
(Seshaiah et al., 2001)
sd-10
(Babcock et al., 2003)
l(3)85Da
(Seshaiah et al., 2001)
ms(3)85E
(Matthews, 1998.8.27)
l(3)85Dd
(Seshaiah et al., 2001)
l(3)85Dh
(Seshaiah et al., 2001)
l(3)85Ee
(Seshaiah et al., 2001)
l(3)85Eh
(Seshaiah et al., 2001)
l(3)85Di
(Seshaiah et al., 2001)
l(3)85Df
(Seshaiah et al., 2001)
l(3)85Ei
(Seshaiah et al., 2001)
l(3)85Dc
(Seshaiah et al., 2001)
ms(3)Z2203
(Ceprani et al., 2008)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Kap-α1
(Mathe et al., 2000)
stwl
(BDGP Project Members, 1994-1999)
sens
(Salzberg et al., 1997)
pum
(Spradling et al., 1999)
neur
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
βTub85D
(Kemphues et al., 1983)
Ras85D
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
MED6
(Gim and Kim, 1998)
tws
(Spradling et al., 1999)
knk
(Ostrowski et al., 2002)
jumu
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
pros
(BDGP Project Members, 1994-1999)
cpo
(BDGP Project Members, 1994-1999)
hth
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
ms(3)85D
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
tho
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
l(3)01728
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
l(3)j9A5
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
l(3)04837
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
l(3)05430
(BDGP Project Members, 1994-1999)
l(3)05652
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
l(3)09656
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
stretch
(BDGP Project Members, 1994-1999)
l(3)s2681
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
Mow
(Bhadra and Birchler, 1996)
Su(var)3-4
(Reuter et al., 1986)
Invadolysin
(McHugh, 1999.10.4)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Deficient embryos show an uninterpretable mutant midgut phenotype.
(Bilder and Scott, 1995)
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
(Duffy et al., 1996)
Embryonic lethal.
(Mansfield et al., 1994)
Heterozygosity for Df(3R)by10 results in 0.7% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
(Harris et al., 2003)
Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.
(Pauli et al., 1995)
Homozygous embryos are very abnormal compared to wild-type.
(Harbecke and Lengyel, 1995)
Homozygous embryos have abnormal gut morphology.
(Merabet et al., 2002)
In a sev6/Y, SosJC2/+ background, the percentage of ommatidia with R7 cells drops, in heterozygotes, from the 16% of sev6/Y, SosJC2/+ to 0%.
(Kolodkin et al., 1994)
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
(Halsell and Kiehart, 1998)
Poor gut differentiation.
(Smith et al., 1993)
Shows a dose-sensitive interaction with pbhs.PB.
(Boube et al., 1997)
Shows dominant enhancement of dominant haltere phenotype caused by Ubx195 and Ubx9.22.
(Burnette et al., 1999)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
Suppression of the rough eye phenotype (formation of extra R7 cells) caused by P{sev-svp2} and enhancement of the P{ro-svp1} rough eye phenotype (loss of one or more outer photoreceptors from many of the ommatidia).
(Kramer et al., 1995)
Suppressor of the dosage dependent (two or more copies of P{sev-svp1} or P{sev-svp2}) transformation of cone cells into R7 photoreceptors and at a lower frequency R7 cells into outer photoreceptors.
(Begemann et al., 1995)
The Df(3R)by10 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,wvar}2Lt insertion).
(Mason et al., 2004)
hide Position Effect Variegation Data
  
hide Stocks ( 2 )
Bloomington
1931
Df(3R)by10, red1 e1/TM3, Sb1 Ser1
Kyoto
106726
Df(3R)by10, red1 e1/TM3, Sb1 Ser1
hide Notes on Origin
Discoverer
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      knk has been found to complement Df(3R)by10, contradicting earlier work (FBrf0041709).
      (Ostrowski et al., 2002)
      hide Synonyms & Secondary IDs ( 6 )
      Reported As
      Symbol Synonym
      by10
      (Fuller, 1986)
      Df(2L)by10
      (Kotarski et al., 1998)
      Df(3R)by-10
      (Boube et al., 1997, Mayer-Jaekel and Hemmings, 1995)
      Df(3R)by10
      (Ceprani et al., 2008)
      Df(3R)by10
      (Palladino et al., 2002, Kemphues et al., 1980, Craig and Brink, 1996, Bhadra and Birchler, 1996, Reuter et al., 1986, Jurgens, 1985, Mansfield et al., 1994)
      Name Synonym
      Deficiency (3R) blistery
       
      Secondary FlyBase IDs
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        Ceprani et al., 2008, BMC Genet. 9: 32
        Autosomal mutations affecting Y chromosome loops in Drosophila melanogaster. [FBrf0204958]
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