Aberration Dmel\Df(3R)cu

General Information
Symbol	Dmel\Df(3R)cu	Species	D. melanogaster
Name		FlyBase ID	FBab0002750
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	hth << bk1 << Su(var)3-14 << cu << bk2 << mus309
Sequence coordinates
Deleted segment	86C1--86D8
Duplicated segment
Computed Breakpoints include	86C1-86C2;86D8
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Pauli et al., 1995, Ashburner et al., 1981, Ohnishi and Voelker, 1982, Landecker et al., 1994, Salzberg et al., 1997)
Breakpoints	86C1-86C2;86D8 (Ashburner et al., 1981, Ohnishi and Voelker, 1982, Landecker et al., 1994, Pauli et al., 1995, Salzberg et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0036112)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	neur (Jurgens et al., 1984) Fdh (Ohnishi and Voelker, 1982) Su(var)3-14 (Reuter et al., 1987)
Partially deleted / disrupted	pros (Balakireva et al., 2000)
Molecular Data
Completely deleted	Rbp1 (Kumar and Lopez, 2005)
Genes NOT Deleted / Disrupted
Complementation Data
	mus309 (Szabad, 1998.4.8) Pp1-87B (Reuter et al., 1987) Su(var)3-7 (Reuter et al., 1987) hth (Salzberg et al., 1997) E(var)87F (Reuter et al., 1987) l(3)87Ae (Szabad, 1998.4.8) Su(var)3-13 (Reuter et al., 1987)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments
	pros^V1/Df(3R)cu results in semi-lethality. (Balakireva et al., 2000)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) No eye pigment phenotype in heterozygotes. (Rong and Golic, 1998)
Position Effect Variegation Data

Stocks ( 5 )
Bloomington	512 Df(3R)cu, Sb¹/TM6B, Tb¹ 771 Df(3R)cu, Sb¹ e^*/TM6B, Tb¹
Kyoto	105952 Df(3R)cu, Sb¹/TM6B, Tb¹ 106075 Df(3R)cu, Sb¹ e^*/TM6B, Tb¹ 101608 Df(3R)cu, Sb¹ / TM6, Hn^P ss^aP88 Ubx^bx-34e Ubx^P15 e¹
Notes on Origin
Discoverer	Holden. J. Holden. (Ashburner et al., 1981)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(3R)cu (Neuburger et al., 2006) Df(3R)cu40 (Balakireva et al., 2000, Pauli et al., 1995, ) Df(3R)cu⁴⁰ (Wustmann et al., 1989, Burkhart et al., 1984, Ohnishi and Voelker, 1982, Ashburner et al., 1981, Jurgens et al., 1984, Reuter et al., 1987)
Name Synonym
Secondary FlyBase IDs

References ( 18 )
Research paper	Neuburger et al., 2006, Genetics 173(3): 1377--1387 A genetic suppressor of two dominant temperature-sensitive lethal proteasome mutants of Drosophila melanogaster is itself a mutated proteasome subunit gene. [FBrf0194466] Kumar and Lopez, 2005, EMBO J. 24(14): 2646--2655 Negative feedback regulation among SR splicing factors encoded by Rbp1 and Rbp1-like in Drosophila. [FBrf0187511] Rong and Golic, 2001, Genetics 157(3): 1307--1312 A targeted gene knockout in Drosophila. [FBrf0134649] Balakireva et al., 2000, J. Neurosci. 20(9): 3425--3433 The genetic variant voila(1) causes gustatory defects during Drosophila development. [FBrf0126996] Rong and Golic, 1998, Genetics 150(4): 1551--1566 Dominant defects in Drosophila eye pigmentation resulting from a euchromatin-heterochromatin fusion gene. [FBrf0105915] Salzberg et al., 1997, Genetics 147(4): 1723--1741 P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: Mutations affecting embryonic PNS development. [FBrf0099763] Pauli et al., 1995, Genetics 139(2): 713--732 Identification of regions interacting with ovo<up>D</up> mutations: Potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. [FBrf0080317] Pauli et al., 1995, D. I. S. 76: 107--124 Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455] Landecker et al., 1994, Dev. Genet. 15(5): 425--434 Screen for enhancers of Polycomb and Polycomblike in Drosophila melanogaster. [FBrf0076124] Wustmann et al., 1989, Molec. gen. Genet. 217: 520--527 The genetics of position-effect variegation modifying loci in Drosophila melanogaster. [FBrf0050576] Reuter et al., 1987, Molec. gen. Genet. 210: 429--436 Modifiers of position-effect variegation in the region from 86C to 88B of the Drosophila melanogaster third chromosome. [FBrf0047003] Burkhart et al., 1984, Genetics 107: 295--306 Characterization of allozyme null and low activity alleles from two natural populations of Drosophila melanogaster. [FBrf0040944] Jurgens et al., 1984, Roux Arch. dev. Biol. 193: 283--295 Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. [FBrf0041709] Ohnishi and Voelker, 1982, D. I. S. 58: 120 New data on genetic and cytogenetic localizations of esterase-C and octanol dehydrogenase in Drosophila melanogaster. [FBrf0037706] Ashburner et al., 1981, D. I. S. 56: 186--191 Report of New Mutants. [FBrf0036112]
Personal communication to FlyBase	Szabad, 1998.4.8, mus309 et al. mus309 et al. [FBrf0102100]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]