A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(3R)dsx2M

General Information
SymbolDmel\Df(3R)dsx2MSpeciesD. melanogaster
NameDeficiency (3R) doublesexFlyBase IDFBab0002761
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data Ta << bk1 << hat << Est-9 << bk2 << dsx
Sequence coordinates
Deleted segment84C1--84E1
Duplicated segment
Computed Breakpoints include [];84E1--2 84C1-84C2;84E1
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
dsxM
 
Mutagen
X ray
(Agnel et al., 1989)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Agnel et al., 1989, Kerridge and Thomas-Cavallin, 1988, Baker et al., 1991, Cavener et al., 1986, Spackman et al., 1994, Salzberg et al., 1997)
Breakpoints
84C1-84C2;84E1
(Cavener et al., 1986)
84C;84E1-84E2
(Kerridge and Thomas-Cavallin, 1988)
84B-84C;84E1-84E2
(Agnel et al., 1989)
84C1-84C2;84E1-84E2
(Baker et al., 1991)
[];84E1--2
(Spackman et al., 1994)
84C1-84C3;84E1
(Salzberg et al., 1997)
Causes alleles
Alhdsx2M
(Perrin and Dura, 2004)
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Proximal (84C1-3) breakpoint estimated to be at about +26 to +27 kb, based on location of 84C1-2 breaks of T(2;3)Ta1 at +34 kb and Df(3R)Scr2 at +41 kb (Baker and Wolfner, 1988, Genes Dev. 2: 477-89)
 
Breakpoint(s) molecularly mapped
(Agnel et al., 1989)
hide Comments on Cytology
Left limit of break 1 from polytene analysis (FBrf0044420) Right limit of break 1 from inclusion of hat (FBrf0044420) Left limit of break 2 from inclusion of dsx (FBrf0049832) Right limit of break 2 from polytene analysis (FBrf0044420)
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
αTub84D
(Lindsley and Zimm, 1992)
α-Est7
(Spackman et al., 1994)
α-Est9
(Spackman et al., 1994)
sas
(Cavener et al., 1986)
Gld
(Cavener et al., 1986)
Alh
(Perrin and Dura, 2004)
Mlp84B
(Perrin and Dura, 2004)
dsx
(Agnel et al., 1989)
rue
(Cavener et al., 1986)
l(3)84Ce
(Cavener et al., 1986)
ted
(Cavener et al., 1986, Baker et al., 1991)
l(3)84Db
(Baker et al., 1991)
Est-C
(Cavener et al., 1986)
l(3)84Dc
(Baker et al., 1991)
l(3)84Da
(Baker et al., 1991)
hat
(Cavener et al., 1986, Baker et al., 1991)
l(3)84Cb
(Cavener et al., 1986)
l(3)84Dd
(Baker et al., 1991)
lap
(Babcock et al., 2003)
gfzf
(Provost et al., 2006, Cavener et al., 1986)
rn
(Cavener et al., 1986, Agnel et al., 1989, Baker et al., 1991)
Partially deleted / disrupted
dsx
(Baker et al., 1991)
Molecular Data
Partially deleted
Alh
(Perrin and Dura, 2004)
hide Genes NOT Deleted / Disrupted
Complementation Data
αTub84B
(Cavener et al., 1986, Hays et al., 1989, Baker et al., 1991)
grn
(Baker et al., 1991)
eIF4AIII
(Baker et al., 1991)
l(3)84Fb
(Baker et al., 1991)
l(3)84Fm
(Baker et al., 1991)
l(3)84Fd
(Baker et al., 1991)
l(3)84Ee
(Baker et al., 1991)
l(3)84Ff
(Baker et al., 1991)
l(3)84Fc
(Baker et al., 1991)
l(3)84Fh
(Baker et al., 1991)
l(3)84Fg
(Baker et al., 1991)
l(3)84Bc
(Cavener et al., 1986)
l(3)84Ed
(Baker et al., 1991)
l(3)84Ei
(Baker et al., 1991)
l(3)84Eb
(Baker et al., 1991)
stk
(Cavener et al., 1986)
l(3)84Fj
(Baker et al., 1991)
l(3)84Fk
(Baker et al., 1991)
l(3)84Ef
(Baker et al., 1991)
l(3)84Fl
(Baker et al., 1991)
l(3)84Eg
(Baker et al., 1991)
mab
(Cavener et al., 1986)
l(3)84Ec
(Baker et al., 1991)
l(3)84Ea
(Baker et al., 1991)
misn
(Salzberg et al., 1997)
l(3)84Fe
(Baker et al., 1991)
l(3)84Bb
(Cavener et al., 1986)
puc
(Baker et al., 1991)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
Affects the "roe" (roughened eye) function of the rn locus.
(Agnel et al., 1989)
Affects both the "roe" (roughened eye) and "rn" (rotund) functions of the rn locus.
(Baker et al., 1991, Cavener et al., 1986)
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Males fertile when in combination with αTub84B7.
(Hays et al., 1989)
The Df(3R)dsx2M chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,wvar}2Lt insertion).
(Mason et al., 2004)
hide Position Effect Variegation Data
  
hide Stocks ( 2 )
Bloomington
1862
Df(3R)dsx2M/TM2
Kyoto
106538
Df(3R)dsx2M/TM2
hide Notes on Origin
Discoverer
Revertant
 
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      hide Synonyms & Secondary IDs ( 10 )
      Reported As
      Symbol Synonym
      Df(2R)dsx2M
      (Salzberg et al., 1997)
      Df(3R)dsx2
      (Moehring and Mackay, 2004)
      Df(3R)dsx2m
      (Provost et al., 2006)
      Df(3R)dsx2M
       
      Df(3R)dsxM+R2
      (Perrin and Dura, 2004, Schonbaum et al., 1992, Clark, 1994, Baker et al., 1991)
      Df(3R)dsxMas+R2
      (Spackman et al., 1994, Cavener et al., 1986, Hays et al., 1989, Kerridge and Thomas-Cavallin, 1988, Agnel et al., 1989, )
      Df(3R)dsx-M+R2
       
      Df(3R)ScxMas+R2
      (Cavener et al., 1986)
      Df dsx[M+R2]
      (Iida and Cavener, 2004)
      Name Synonym
      Deficiency (3R) doublesex
       
      Secondary FlyBase IDs
        hide References ( 21 )
        Generate a list of
        List References by type
        hide Recent research papers ( 1 )
        Provost et al., 2006, Genetics 172(1): 207--219
        Loss-of-function mutations in a glutathione S-transferase suppress the prune-Killer of prune lethal interaction. [FBrf0190760]
        Show all research papers ...