Aberration Dmel\Df(3R)e-N19

General Information
Symbol	Dmel\Df(3R)e-N19	Species	D. melanogaster
Name	Deficiency (3R) ebony	FlyBase ID	FBab0002781
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	Atpα << bk1 << l(3)03773 << sar1 << bk2 << epsin-like
Sequence coordinates
Deleted segment	93B2--94A8
Duplicated segment
Computed Breakpoints include	93B2-93B13;94A3-94A8
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Newby and Jackson, 1991)
Class of aberration (relative to progenitor)	chromosomal_deletion (Jurgens et al., 1984, Bodmer et al., 1990, Pauli et al., 1995, Newby and Jackson, 1991, Cobb, 1996, Harbecke and Lengyel, 1995, Prout et al., 1997, Lo and Frasch, 1997, Price et al., 1997)
Breakpoints	93B;94 (Lo and Frasch, 1997, Price et al., 1997, Newby and Jackson, 1991, Pauli et al., 1995, Cobb, 1996, Prout et al., 1997) 93B;94A (Jurgens et al., 1984, Bodmer et al., 1990, Harbecke and Lengyel, 1995)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from non-inclusion of Atpα (FBrf0067338) Right limit of break 1 from polytene analysis (FBrf0041709) Left limit of break 2 from inclusion of sar1 (FBrf0067338) Right limit of break 2 from non-inclusion of epsin-like (FBrf0067338) Ref: Garcia-Bellido et al., 1983, Molec. gen. Genet. 192: 253--263 (Jurgens et al., 1984)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Rab11 (Jankovics et al., 2001) mod(mdg4) (BDGP Project Members, 1994-1999, Spradling et al., 1999) tin (Harbecke and Lengyel, 1995) E2f (BDGP Project Members, 1994-1999, Spradling et al., 1999) InR (BDGP Project Members, 1994-1999, Spradling et al., 1999) sar1 (BDGP Project Members, 1994-1999, Spradling et al., 1999) how (BDGP Project Members, 1994-1999, Prout et al., 1997, Lo and Frasch, 1997, Spradling et al., 1999, Kankel et al., 2004) l(3)03773 (BDGP Project Members, 1994-1999, Spradling et al., 1999) l(3)L7012 (BDGP Project Members, 1994-1999) l(3)S086802 (Szeged Stock Center, 1998-) l(3)S012719 (Szeged Stock Center, 1998-) l(3)S005042 (Szeged Stock Center, 1998-) E(Egfr)C22 (Price et al., 1997) E(ftz)4038 (Kankel et al., 2004)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	rtet (Spradling et al., 1999) slmb (BDGP Project Members, 1994-1999) cnc (BDGP Project Members, 1994-1999) Atpα (BDGP Project Members, 1994-1999, Spradling et al., 1999) pnt (BDGP Project Members, 1994-1999) hh (BDGP Project Members, 1994-1999, Spradling et al., 1999) l(3)j2B1 (BDGP Project Members, 1994-1999) l(3)S101712 (Szeged Stock Center, 1998-) l(3)S092405 (Szeged Stock Center, 1998-) l(3)S091306 (Szeged Stock Center, 1998-) l(3)S026420 (Szeged Stock Center, 1998-) Indf (Cobb, 1996) epsin-like (BDGP Project Members, 1994-1999, Spradling et al., 1999)
Molecular Data
	Calx (Wang et al., 2005)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
	sec15 (Mehta et al., 2005)
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Deficient embryos show an uninterpretable mutant midgut phenotype. (Bilder and Scott, 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Homozygous embryos have abnormal gut morphology. (Merabet et al., 2002) Homozygous embryos show incomplete tracheal formation. Midgut primordia do not fuse and Malpighian tubules are variable in length. (Harbecke and Lengyel, 1995) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) The Df(3R)e-N19 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Wild type nonanol phenotype; repulsion. (Cobb, 1996)
Position Effect Variegation Data

Stocks ( 3 )
Bloomington	2425 Df(3R)e-N19/TM2
Kyoto	107325 Df(3R)e-N19/TM2 103308 Df(3R)e-N19 / TM2, Ubx¹³⁰ e^s
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(3R)e^N19 (Brumby et al., 2004, Jurgens et al., 1984) Df(3R)eN19 (Kankel et al., 2004) Df(3R)e-n19 (Gildea et al., 2000) Df(3R)e-N19 (Wang et al., 2005, Mehta et al., 2005) e-N19 (Yamaguchi et al., 1999)
Name Synonym	Deficiency (3R) ebony
Secondary FlyBase IDs

References ( 46 )

Generate a list of	All references relating to this aberration ( 46 )

List References by type	Research paper ( 42 ) FlyBase analysis ( 1 ) Computer file ( 2 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2006 Show research papers ...