|Name||Deficiency (3R) red Malpighian tubules||FlyBase ID||FBab0002874|
|Also Known As||Df(3R)redp52, Df(3R)redP52|
|Computed Breakpoints include||88A4;88B1-88B2|
|Map ( GBrowse )||
No matching regions found.
3R:10,135,368..10,137,917 [+] (Df(3R)red-P52:bk2)
|Member of large scale dataset(s)|
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data||ems << bk1 << mei-P19 << RpII15 << bk2 << spn-B|
|Genetic mapping information|
|Comments on Cytology|
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Completely deleted / disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
|NOT in combination with other aberrations|
Heterozygotes show abnormal temperature-preference behaviour; their avoidance index against low temperatures is reduced compared to wild type.
Heterozygosity for Df(3R)red-P52 results in 3.4% X chromosome nondisjunction and 1.7% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
Df(3R)red-P52 is hemizygous embryonic lethal. 10.5% of heterozygous adults show at least one homeotic transformation phenotype.
Flies heterozygous for both Df(3R)red-P52 and Ubx mutations in the abx regulatory region have an increased frequency of the trx bithorax-variegated phenotype (partial transformation of T3 to T2, mostly in the anterior compartment). Flies heterozygous for both Df(3R)red-P52 and Ubx mutations in the pbx regulatory region have an increased frequency of the trx bithorax-variegated phenotype, although a large fraction of the transformations are to posterior T3 structures. Flies heterozygous for both Df(3R)red-P52 and Ubx mutations in the bx and bxd regulatory regions show no increase in the trx bithorax-variegated phenotype, except Ubxbx-F31 and Ubxbx-34eprv which both overlap the region affected by abx deletions.
The A1 transformation phenotype of ftzUal alleles is suppressed in Df(3R)red-P52 / ftzUal allele heterozygotes. The haltere to wing transformation of ftzRpl is slightly enhanced in ftzRpl / Df(3R)red-P52 heterozygotes.
Heterozygotes sometimes have transformations typical of bithorax or postbithorax mutants.
Df(3R)red/+ progeny of Df(1)C128/+ females show a high frequency of homeotic transformations (Gans et al., 1980).
|Stocks ( 6 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
Second breakpoint not reported.
|Synonyms & Secondary IDs ( 6 )|
(Maixner et al., 1998, Breen et al., 1995, Henchoz et al., 1996, Capdevila and Garcia-Bellido, 1981, Harrison et al., 1989, Castelli-Gair and Garcia-Bellido, 1990, Duncan, 1986, Chinwalla et al., 1995, Kelley, 1993, Harrison et al., 1992, Mortin et al., 1992, Parkhurst et al., 1988, Breen and Harte, 1991)
Deficiency (3R) red Malpighian tubules
|Secondary FlyBase IDs|
|References ( 33 )|
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|Recent research papers ( 1 )|