Aberration Dmel\Df(3R)tll-e
| General Information | |||
|---|---|---|---|
| Symbol | Dmel\Df(3R)tll-e | Species | D. melanogaster |
| Name | Deficiency (3R) tailless | FlyBase ID | FBab0002938 |
| Feature type | chromosomal_deletion | Created / Updated | 2006-08-22/2006-08-22 |
| Formalized genetic data | wts << bk1 << l(3)EGX4 << bv << bk2 << rod | ||
| Sequence coordinates | |||
| Deleted segment | 100A2--100C3 | ||
| Duplicated segment | |||
| Computed Breakpoints include | 100A2;100C2-100C3 | ||
| Breakpoints Inherited | |||
Nature of the Aberration
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| Cytological Order | |||
| Progenitor | |||
| Mutagen | |||
| Class of aberration (relative to progenitor) | |||
| Breakpoints | 100A1;100C1 100A2-100A5;100C2-100C3 | ||
| Causes alleles | |||
| Carries alleles | |||
| Transposon Insertions | |||
| Genetic mapping information | |||
| Comments | Homozygous deficiency embryos show six instead of seven ftz protein stripes (Mahoney and Lengyel, 1987) | ||
Comments on Cytology
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Left limit of break 1 from polytene analysis (FBrf0079656) Right limit of break 1 from polytene analysis (citation unavailable) Limits of break 2 from polytene analysis (FBrf0079656) | |||
Molecularly Mapped Breakpoints
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Sequence Crossreferences
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| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | ||
Gene Deletion & Duplication Data
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Genes Deleted / Disrupted
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| Complementation Data | |||
| Completely deleted / disrupted | |||
| Molecular Data | |||
Genes NOT Deleted / Disrupted
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| Complementation Data | |||
| Molecular Data | |||
Genes Duplicated
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| Complementation Data | |||
| Molecular Data | |||
Genes NOT Duplicated
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| Complementation Data | |||
| Molecular Data | |||
Related Comments
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Phenotypic Data
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| In combination with other aberrations | |||
| NOT in combination with other aberrations | Does not give a Minute phenotype when heterozygous. During cellularization in Df(3R)tll-e homozygous embryos, the microfilament rings at the base of the furrow canals constrict prematurely. The rings squeeze the nuclei into dumbbell shapes during early cellularization, trapping and dragging some of them along with the advancing cellularization front during late cellularization. Individuals have an abnormal dorsal cephalopharyngeal apparatus. Lack hindgut, Malpighian tubules and much of the posterior midgut. During cellularization of Df(3R)tll-e embryos (which are deficient for bnk), actin rings constrict prematurely, pinching the nuclei and causing the \'bottleneck\' phenotype. | ||
Position Effect Variegation Data
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Stocks
( 2 ) | |||
| Bloomington | |||
| Kyoto | |||
Notes on Origin
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| Discoverer | |||
Balancer / Genotype Variants of the Aberration
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Separable Components
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Other Comments
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The Df(3R)tll-e chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(3R)tll-e overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. | |||
Synonyms & Secondary IDs
( 4 ) | |||
| Reported As | |||
| Symbol Synonym | Df(3R)tlle Df(3R)tll-e | ||
| Name Synonym | Deficiency (3R) tailless | ||
| Secondary FlyBase IDs | |||
References
( 27 ) | |||
| Generate a list of | |||
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Recent research papers ( 2 ) | |||
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Nature of the Aberration