FlyBase Aberration Report: Dmel\Df(4)G

General Information

Symbol

Df(4)G

Species

D. melanogaster

Name

Deficiency (4) of Gloor and Green

FlyBase ID

FBab0002954

Feature type

chromosomal_deletion

Computed Breakpoints include

102E2-102E7;102E-102F2

Features within 102E2--102F2 Features within 102F8--102F8 (Estimated cytology)

Genomic Maps

JBrowse

Sequence coordinates

4:721,173..776,474 (Df(4)G:bk1)

(Cook, 2016.2.8)

4:1,072,384..1,078,562 (Df(4)G:bk1)

(Podemski et al., 2004)

4:1,172,469..1,350,131 (Df(4)G:bk2)

(Cook, 2016.2.8)

4:1,348,131..1,348,131 (Df(4)G:bk2)

(Podemski et al., 2004)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

T(1;4)G

Mutagen

recombination

Class of aberration (relative to wild type)

chromosomal_deletion

Class of aberration (relative to progenitor)

Breakpoints

102E2;4Rt;[102E2-102E2];[4Rt-4Rt];

(Podemski et al., 2004)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Genetic mapping information

Comments

The 4:1172469..1350131 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of pho, which published results say is deleted. The right extent corresponds to the right end of chromosome 4 genome assembly.

(Cook, 2016.2.8)

The 4:721173..776474 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of ey, which published results say is not deleted. The right extent corresponds to the right end of bt, which published results say is deleted.

(Cook, 2016.2.8)

Comments on Cytology

Terminal deficiency. The chromosome also carries a second site mutation in the bt gene.

(Podemski et al., 2004)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Hochman, 1971)

CaMKII

(Hochman, 1976, Hochman, 1974, Hochman, 1971)

l(4)102EFa

(Hochman, 1976, Hochman, 1974, Hochman, 1971)

l(4)102EFd

(Hochman, 1976, Hochman, 1974, Hochman, 1971)

l(4)102EFf

(Hochman, 1976, Hochman, 1974, Hochman, 1971)

l(4)ry1

(Stronach, 2001.11.29, Stronach, 1997.6.18)

pho

(Simon et al., 1992, Hochman, 1976, Hochman, 1974, Hochman, 1971)

(Kronhamn et al., 2002, Hochman, 1976, Hochman, 1974, Hochman, 1971, Hochman et al., 1964)

toy

(Kronhamn et al., 2002)

Partially deleted / disrupted

Molecular Data

Completely deleted

Actβ

(Podemski et al., 2004)

Arf4

(Podemski et al., 2004)

Cadps

(Podemski et al., 2004)

Cals

(Podemski et al., 2004)

CG32017

(Podemski et al., 2004)

CG33521

(Podemski et al., 2004)

Kif3C

(Podemski et al., 2004)

pho

(Podemski et al., 2004)

ukar

(Podemski et al., 2004)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Hochman et al., 1964)

(Hochman, 1971, Hochman et al., 1964)

(Kronhamn et al., 2002, Hochman et al., 1964)

fs(4)34

(Hochman, 1974)

gvl

(Hochman et al., 1964)

(Hochman, 1976)

l(4)102ABd

(Hochman, 1971, Hochman et al., 1964)

l(4)102ABf

(Hochman, 1971)

l(4)102ABh

(Hochman, 1971, Hochman et al., 1964)

(Hochman, 1971)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Kronhamn et al., 2002, Scully, 1999.3.7, Hochman, 1971)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1976)

(Hochman, 1971, Hochman et al., 1964)

toy

(Hochman, 1976)

Molecular Data

apolpp

(Podemski et al., 2004)

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Df(4)G/Df(4)3 lethal Df(4)G/Df(4)11 lethal Df(4)G/Df(4)12 lethal Df(4)G/Df(4)24 lethal Df(4)G/Df(4)34 lethal

NOT in combination with other aberrations

Df(4)G does not uncover hybrid sterility when heterozygous in males containing the D.simulans 4th chromosome introgressed into an otherwise D.melanogaster background.

(Masly et al., 2006)

Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22.

(Burnette et al., 1999)

The rate of transmission of the Df(4)G chromosome is similar to that of a normal fourth chromosome.

(Ahmad and Golic, 1998)

Embryos show normal axon guidance.

(Winberg et al., 1998)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Lethal homozygous

Stocks (2)

Kyoto

103321

Df(4)G / ci^D

108917

Df(4)G/In(4)ci^D, ci^D pan^ciD

Notes on Origin

Discoverer

Gloor and Green, 1957.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Def(4)G

(Li-Kroeger et al., 2012)

Df(4)G

(Sawyer et al., 2020, Li-Kroeger et al., 2012, Masly et al., 2006, Podemski et al., 2004)

Df(4)sv-spa

(Hochman et al., 1964)

(Yamaguchi et al., 2001)

Name Synonyms

Deficiency (4) of Gloor and Green

Secondary FlyBase IDs

References (32)

Report Sections

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