Aberration Dmel\Dp(1;1)B

General Information
Symbol	Dmel\Dp(1;1)B	Species	D. melanogaster
Name	Duplication (1;1) Bar	FlyBase ID	FBab0003035
Feature type	tandem_duplication

Computed Breakpoints include	16A1;16A7
Duplicated segment	16A1--16A7
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	spontaneous
Class of aberration (relative to progenitor)	tandem_duplication (Sutton, 1943, Tsubota, 1991, Hall and Kankel, 1976)
Breakpoints	15F9-16A1;16A7-16B1 (Hall and Kankel, 1976) 16A1;16A7 (Sutton, 1943, Tsubota, 1991)
Causes alleles	B¹ (Sutton, 1943, Tsubota, 1991, Epps et al., 1997)
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << B << bk2
Genetic mapping information
Comments	A roo-element insertion at the 16A7 breakpoint. (Tsubota, 1991)
Comments on Cytology
	All limits from polytene analysis (FBrf0005979)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	B (Sutton, 1943)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated	B-H1 (Higashijima et al., 1992)
Molecular Data
Completely duplicated	B-H1 (Bel et al., 2011)
Genes NOT Duplicated
Complementation Data
Molecular Data
	B-H2 (Bel et al., 2011)
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Position-effect apparently resulting from juxtaposition of 16A1 with 16A7, which may undergo mutation to less extreme forms (e.g., Bⁱ). Produces normal and triplicated ^Dp(1;1;1)BB products by unequal crossing over.
Stocks ( 1 )
Kyoto	100992 C(1)DX, y¹ f¹ / Dp(1;1)B, Bⁱ Bⁱ f¹
Notes on Origin
Discoverer	Tice, Feb. 1913. Tice. (Sutton, 1943)

Balancer / Genotype Variants of the Aberration

Separable Components
	Dp(1;1;1)BB
Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	B (Higashijima et al., 1992) B^dup (Sutton, 1943) Dp(1;1)B
Name Synonym	Duplication (1;1) Bar
Secondary FlyBase IDs

References ( 13 )
Research paper	Bel et al., 2011, BMC Res. Notes 4: 84 Quantitative real-time PCR with SYBR Green detection to assess gene duplication in insects: study of gene dosage in Drosophila melanogaster (Diptera) and in Ostrinia nubilalis (Lepidoptera). [FBrf0213521] Epps et al., 1997, Genetics 145(4): 1041--1052 oroshigane, a new segment polarity gene of Drosophila melanogaster, functions in hedgehog signal transduction. [FBrf0093093] Higashijima et al., 1992, Genes Dev. 6(6): 1005--1018 Subtype determination of Drosophila embryonic external sensory organs by redundant homeobox genes BarH1 and BarH2. [FBrf0056098] Norris et al., 1992, Mol. Gen. Genet. 233: 106--112 The identification of the B^S breakpoint and of two possible Bar genes. [FBrf0057261] Tsubota, 1991, Genet. Res. (Camb.) 57: 105--111 Unequal crossing-over within the B duplication of Drosophila melanogaster: a molecular analysis. [FBrf0054076] Hall and Kankel, 1976, Genetics 83: 517--535 Genetics of acetylcholinesterase in Drosophila melanogaster. [FBrf0028767] Sutton, 1943, Genetics 28: 97--107 Bar eye in Drosophila melanogaster: A cytological analysis of some mutations and reverse mutations. [FBrf0005979] Bridges, 1936, Science 83: 210--211 The Bar 'gene' a duplication. [FBrf0003681] Sturtevant, 1925, Genetics 10: 117--147 The effects of unequal crossing over at the Bar locus in Drosophila. [FBrf0001398] Zeleny, 1920, J. exp. Zool. 30: 293--324 A change in the Bar gene of Drosophila melanogaster involving further decrease in facet number and increase in dominance. [FBrf0000991] Tice, 1914, Biol. Bull., Wood's Hole 26: 221--230 A new sex-linked character in Drosophila. [FBrf0000714]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]