Aberration Dmel\In(1)sc⁴

General Information
Symbol	Dmel\In(1)sc⁴	Species	D. melanogaster
Name	Inversion (1) scute	FlyBase ID	FBab0004187
Feature type	chromosomal_inversion
Also Known As	sc⁴

Computed Breakpoints include	1B3;h26-h28
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_inversion (Lindsley and Grell, 1968, Belyaeva et al., 1998)
Breakpoints	1B3-1B4;19F-20C1 (Lindsley and Grell, 1968) 1B3-1B4;h26-h28 (Belyaeva et al., 1998)
Causes alleles	ABO-X¹ (Malva et al., 1985) sc⁴ (Campuzano et al., 1985, Malva et al., 1985, Romani et al., 1989, Cubas et al., 1991, Campuzano and Modolell, 1992, Gomez-Skarmeta et al., 1995)
Carries alleles	y¹
Transposon Insertions
Formalized genetic data	Zhr << bk1 << l(1)sc << bk2 hits ABO-X
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Carramolino et al., 1982, Campuzano et al., 1985, Ruiz-Gomez and Ghysen, 1993) Left breakpoint between DNA coordinates +24.0 and +25.8 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scβ segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).
Comments on Cytology
	The proximal breakpoint is in or near the ABO-X heterochromatic region that maternally interacts with the abo gene product. (Malva et al., 1985) Left limit of break 1 from polytene analysis (FBrf0042024) Right limit of break 1 from complementation mapping against l(1)sc (FBrf0047940) Left limit of break 2 from complementation mapping against ABO-X (FBrf0042645) Right limit of break 2 from polytene analysis (FBrf0105072)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	sc (Campuzano et al., 1985, Campuzano and Modolell, 1992)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	pad (Gibert et al., 2005)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	In(1)sc⁴ causes a loss of all scutellar bristles. (Gibert et al., 2005) Homozygous females show a loss of tergite chaetae. (Mari-Beffa et al., 1991) Maternal and zygotic interactions between abo and In(1)sc⁴ (Malva, Labella, Manzi, Salzano, Lavorgna, De Ponti and Graziani, 1985, Genetics 111: 487-94). In(1)sc⁴/+ female produces about 6% exceptional males from 4-strand double exchange. Secondary exceptions about 4%.
Stocks ( 2 )
Bloomington	789 In(1)sc⁴, y¹ sc⁴ ABO-X¹
Kyoto	101132 In(1)sc⁴, y¹ sc⁴
Notes on Origin
Discoverer	Agol, 1928.
	on a y chromosome
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	In(1)sc4 (Kolesnikova et al., 2001, ) In(1)sc⁴ (Demakova et al., 2007) sc⁴ (Park and Yamamoto, 1995, Leyns et al., 1989, Mari-Beffa et al., 1991)
Name Synonym	Inversion (1) scute
Secondary FlyBase IDs

References ( 36 )

Generate a list of	All references relating to this aberration ( 36 )

List References by type	Research paper ( 28 ) Review ( 4 ) Personal communication to FlyBase ( 1 ) FlyBase analysis ( 1 ) Book ( 2 )
Recent research papers (0)
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Recent reviews (0)
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Aberration Dmel\In(1)sc4

Aberration Dmel\In(1)sc⁴