A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Aberration Dmel\In(1)sc7

General Information
SymbolDmel\In(1)sc7SpeciesD. melanogaster
NameFlyBase IDFBab0004196
Feature typechromosomal_inversionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data bk1 hits sc << bk2
Sequence coordinates
Deleted segment
Duplicated segment
Computed Breakpoints include 1B4;6D8
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
 
Class of aberration (relative to progenitor)
Breakpoints
1B4-1B6;5D3-5D6
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Left breakpoint between DNA coordinates -1.8 and -5.9 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scβ segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).
 
Breakpoint(s) molecularly mapped
hide Comments on Cytology
Left limit of break 1 from polytene analysis (FBrf0020044) Right limit of break 1 from polytene analysis (FBrf0109188) Limits of break 2 from polytene analysis (FBrf0109188)
 
Cytology determined by Schultz.
Cytology determined by Lefevre.
2.5 to 3.1kb DNA is deleted in the neighbourhood of the distal chromosome breakpoint.
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Normal disjunction and 33% recombination in In(1)sc7/+ female, 26% secondary nondisjunction and 27% recombination in In(1)sc7/+/Y female (Grell, 1962, Genetics 47: 1737-54). wa removable from the inversion by double crossing over in triploid.
 
hide Position Effect Variegation Data
  
hide Stocks ( 15 )
Bloomington
Kyoto
hide Notes on Origin
Discoverer
Dubinin, 1929.
 
on a wa chromosome
 
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      hide Synonyms & Secondary IDs ( 2 )
      Reported As
      Symbol Synonym
      In(1)sc7
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 17 )
        Research paper
        Gomez-Skarmeta et al., 1995, Genes Dev. 9(15): 1869--1882
        Cis-regulation of achaete and scute: shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs. [FBrf0083155]
        Ray and Rodrigues, 1994, Roux Arch. dev. Biol. 203: 340--350
        The function of the proneural genes achaete and scute in the spatio-temporal patterning of the adult labellar bristles of Drosophila melanogaster. [FBrf0074258]
        Martin-Bermudo et al., 1993, Development 118(3): 1003--1112
        Molecular characterization of the lethal of scute genetic function. [FBrf0066962]
        Cubas et al., 1991, Genes Dev. 5: 996--1008
        Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc. [FBrf0054074]
        Campuzano et al., 1985, Cell 40: 327--338
        Molecular genetics of the achaete-scute gene complex of D. melanogaster. [FBrf0042024]
        Carramolino et al., 1982, EMBO J. 1: 1185--1191
        DNA map of mutations at the scute locus of Drosophila melanogaster. [FBrf0037903]
        Garcia-Bellido, 1979, Genetics 91: 491--520
        Genetic analysis of the achaete-scute system of Drosophila melanogaster. [FBrf0033191]
        Grell, 1962, Genetics 47(12): 1737--1754
        A new model for secondary nondisjunction: The role of distributive pairing. [FBrf0014622]
        Sturtevant and Beadle, 1936, Genetics 21: 554--604
        The relations of inversions in the X chromosome of Drosophila melanogaster to crossing over and disjunction. [FBrf0003535]
        Dubinin, 1933, J. Genet. 27: 443--464
        Step-allelomorphism in Drosophila melanogaster. [FBrf0002571]
        Dubinin, 1930, Zh. eksp. Biol. Med. 6: 300--324
        A study of step allelomorphism in Drosophila melanogaster. [FBrf0002111]
        Serebrovsky and Dubinin, 1930, J. Hered. 21: 259--265
        X-ray experiments with Drosophila. [FBrf0001995]
        Personal communication to FlyBase
        Florence, 1999.7.22, Notes from Brian Florence.
        Notes from Brian Florence. [FBrf0109188]
        FlyBase analysis
        FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type.
        En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
        Book
        Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
        The Genome of Drosophila melanogaster. [FBrf0066905]
        Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp
        Genetic variations of Drosophila melanogaster. [FBrf0020044]
        Bridges and Brehme, 1944, Publs Carnegie Instn 552: vii + 257pp
        The mutants of Drosophila melanogaster. [FBrf0006100]