A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Aberration Dmel\In(1)sc7

General Information
SymbolDmel\In(1)sc7SpeciesD. melanogaster
NameFlyBase IDFBab0004196
Feature typechromosomal_inversion
Computed Breakpoints include 1B4;6D8
Sequence coordinates
Member of large scale dataset(s)
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Description
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FB2013_03
FB2013_02
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hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
 
Class of aberration (relative to progenitor)
Breakpoints
1B4-1B6;5D3-5D6
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data bk1 hits sc << bk2
Genetic mapping information
Comments
Breakpoint(s) molecularly mapped
Left breakpoint between DNA coordinates -1.8 and -5.9 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scβ segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).
 
hide Comments on Cytology
Cytology determined by Lefevre.
2.5 to 3.1kb DNA is deleted in the neighbourhood of the distal chromosome breakpoint.
Cytology determined by Schultz.
Left limit of break 1 from polytene analysis (FBrf0020044) Right limit of break 1 from polytene analysis (FBrf0109188) Limits of break 2 from polytene analysis (FBrf0109188)
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
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hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Homozygous females show a strong loss of tergite chaetae.
Normal disjunction and 33% recombination in In(1)sc7/+ female, 26% secondary nondisjunction and 27% recombination in In(1)sc7/+/Y female (Grell, 1962, Genetics 47: 1737-54). wa removable from the inversion by double crossing over in triploid.
 
hide Stocks ( 10 )
Bloomington
Kyoto
hide Notes on Origin
Discoverer
Dubinin, 1929.
 
on a wa chromosome
 
hide Balancer / Genotype Variants of the Aberration
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hide Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym
Name Synonym
Secondary FlyBase IDs
hide References ( 20 )
Research paper
Carhan et al., 2005, Genes Brain Behav. 4(8): 449--465
Female receptivity phenotype of icebox mutants caused by a mutation in the L1-type cell adhesion molecule neuroglian. [FBrf0190532]
Lear et al., 2005, Neuron 48(2): 221--227
A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior. [FBrf0191322]
Gomez-Skarmeta et al., 1995, Genes Dev. 9(15): 1869--1882
Cis-regulation of achaete and scute: shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs. [FBrf0083155]
Ray and Rodrigues, 1994, Rouxs Arch. Dev. Biol. 203: 340--350
The function of the proneural genes achaete and scute in the spatio-temporal patterning of the adult labellar bristles of Drosophila melanogaster. [FBrf0074258]
Martin-Bermudo et al., 1993, Development 118(3): 1003--1112
Molecular characterization of the lethal of scute genetic function. [FBrf0066962]
Cubas et al., 1991, Genes Dev. 5: 996--1008
Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc. [FBrf0054074]
Mari-Beffa et al., 1991, Rouxs Arch. Dev. Biol. 200(3): 132--142
Genetic and developmental analyses of chaetae pattern formation in Drosophila tergites. [FBrf0055045]
Campuzano et al., 1985, Cell 40: 327--338
Molecular genetics of the achaete-scute gene complex of D. melanogaster. [FBrf0042024]
Carramolino et al., 1982, EMBO J. 1: 1185--1191
DNA map of mutations at the scute locus of Drosophila melanogaster. [FBrf0037903]
Garcia-Bellido, 1979, Genetics 91: 491--520
Genetic analysis of the achaete-scute system of Drosophila melanogaster. [FBrf0033191]
Grell, 1962, Genetics 47(12): 1737--1754
A new model for secondary nondisjunction: The role of distributive pairing. [FBrf0014622]
Sturtevant and Beadle, 1936, Genetics 21: 554--604
The relations of inversions in the X chromosome of Drosophila melanogaster to crossing over and disjunction. [FBrf0003535]
Dubinin, 1933, J. Genet. 27: 443--464
Step-allelomorphism in Drosophila melanogaster. [FBrf0002571]
Dubinin, 1930, Zh. eksp. Biol. Med. 6: 300--324
A study of step allelomorphism in Drosophila melanogaster. [FBrf0002111]
Serebrovsky and Dubinin, 1930, J. Hered. 21: 259--265
X-ray experiments with Drosophila. [FBrf0001995]
Personal communication to FlyBase
Florence, 1999.7.22, Notes from Brian Florence.
Notes from Brian Florence. [FBrf0109188]
FlyBase analysis
FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type.
En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book
Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
The Genome of Drosophila melanogaster. [FBrf0066905]
Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp
Genetic variations of Drosophila melanogaster. [FBrf0020044]
Bridges and Brehme, 1944, Publs Carnegie Instn 552: vii + 257pp
The mutants of Drosophila melanogaster. [FBrf0006100]