Aberration Dmel\In(1)sc8
| General Information | |||
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| Symbol | Dmel\In(1)sc8 | Species | D. melanogaster |
| Name | FlyBase ID | FBab0004197 | |
| Feature type | chromosomal_inversion | ||
| Computed Breakpoints include | 1B2;h32 | ||
| Sequence coordinates | |||
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| Description |
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| FB2012_01 |
Stocks
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| FB2011_10 |
Stocks
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
Nature of the Aberration
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| Cytological Order | |||
| Progenitor | |||
| Mutagen | |||
| Class of aberration (relative to progenitor) | |||
| Breakpoints | 1B2-1B3;20B-20D1 1B2-1B3;h32 | ||
| Causes alleles | |||
| Carries alleles | |||
| Transposon Insertions | |||
| Formalized genetic data | ac << bk1 << Zhr << bb << bk2 | ||
| Genetic mapping information | |||
| Comments | Breakpoint(s) molecularly mapped Left breakpoint between DNA coordinates 46.8 and 47.9 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scβ segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92). | ||
Comments on Cytology
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Left limit of break 1 from polytene analysis (FBrf0042024) Right limit of break 1 from complementation mapping against sc (FBrf0047940) Limits of break 2 from polytene analysis (FBrf0058564) | |||
Sequence Crossreferences
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| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | ||
Gene Deletion & Duplication Data
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Genes Deleted / Disrupted
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| Complementation Data | |||
| Completely deleted / disrupted | |||
| Molecular Data | |||
Genes NOT Deleted / Disrupted
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| Complementation Data | |||
| Molecular Data | |||
Genes Duplicated
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| Complementation Data | |||
| Molecular Data | |||
Genes NOT Duplicated
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| Complementation Data | |||
| Molecular Data | |||
Related Comments
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Phenotypic Data
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| In combination with other aberrations | |||
| NOT in combination with other aberrations | Mutants are viable and have normal bristle pigmentation. Weak mutant for sc and shows a Hw effect. variegates for ac, y, and probably l(1)1Ac (Hess, 1962) in X0 male. Left break between ac and sc because induced deficiencies for the terminal uninverted portion of In(1)sc8 are deficient for y and ac but not sc8 (Patterson and Stone, 1935) and because In(1)sc8Lsc4R is deficient for sc (Sturtevant and Beadle, 1936); <up>i.e., for the α subdivision of the sc locus (Garcia-Bellido)</up>. Right break between bb and centromere because deficiencies for terminal genes are frequently deficient for bb (Patterson, 1933, Genetics 18: 32-52) as is In(1)sc4Lsc8R (Gershenson, 1933, J. Genet. 28: 297-313; Sturtevant and Beadle, 1936). In(1)sc8/+ female produces about 3% exceptional sons from 4-strand double crossing over within the inversion and about 8.7% recombination. In(1)sc8/+/Y female produces 19% secondary nondisjunction and 12% recombination (Sturtevant and Beadle, 1936; Grell, 1962, Genetics 47: 1737-54). In(1)sc8/0 partially male lethal (Baker, 1971; Johnson, Harger and Holm, 1979); variegates for y; ac enhanced. | ||
Stocks
( 304 ) | |||
| Bloomington | |||
| Kyoto | 102040 101137 | ||
Notes on Origin
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| Discoverer | Sidorov, 1929. | ||
Balancer / Genotype Variants of the Aberration
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Separable Components
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Other Comments
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"position-effect variegation for: l(1)1Ac" was stated as tentative. | |||
Synonyms & Secondary IDs
( 3 ) | |||
| Reported As | |||
| Symbol Synonym | In(1)sc8 In(1)sc8 | ||
| Name Synonym | |||
| Secondary FlyBase IDs | |||
References
( 53 ) | |||
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Recent research papers (0)
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| All research papers listed in FlyBase were published before 2010 | |||
Recent reviews (0)
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| All reviews listed in FlyBase were published before 2010 | |||
Recent Updates