A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Aberration Dmel\In(1)sc8

General Information
SymbolDmel\In(1)sc8SpeciesD. melanogaster
NameFlyBase IDFBab0004197
Feature typechromosomal_inversion
Computed Breakpoints include 1B2;h32
Sequence coordinates
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Description
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FB2012_01
Stocks
FB2011_10
Stocks
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hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
 
Class of aberration (relative to progenitor)
Breakpoints
1B2-1B3;20B-20D1
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data ac << bk1 << Zhr << bb << bk2
Genetic mapping information
Comments
Left breakpoint between DNA coordinates 46.8 and 47.9 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scβ segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).
 
hide Comments on Cytology
Left limit of break 1 from polytene analysis (FBrf0042024) Right limit of break 1 from complementation mapping against sc (FBrf0047940) Limits of break 2 from polytene analysis (FBrf0058564)
 
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DDBJ /
EMBL /
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DNA sequence
Protein sequence
Name
 
 
 
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Complementation Data
Completely deleted / disrupted
Molecular Data
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Complementation Data
Molecular Data
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Complementation Data
Molecular Data
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Complementation Data
Molecular Data
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In combination with other aberrations
NOT in combination with other aberrations
Mutants are viable and have normal bristle pigmentation.
Weak mutant for sc and shows a Hw effect. variegates for ac, y, and probably l(1)1Ac (Hess, 1962) in X0 male. Left break between ac and sc because induced deficiencies for the terminal uninverted portion of In(1)sc8 are deficient for y and ac but not sc8 (Patterson and Stone, 1935) and because In(1)sc8Lsc4R is deficient for sc (Sturtevant and Beadle, 1936); <up>i.e., for the α subdivision of the sc locus (Garcia-Bellido)</up>. Right break between bb and centromere because deficiencies for terminal genes are frequently deficient for bb (Patterson, 1933, Genetics 18: 32-52) as is In(1)sc4Lsc8R (Gershenson, 1933, J. Genet. 28: 297-313; Sturtevant and Beadle, 1936). In(1)sc8/+ female produces about 3% exceptional sons from 4-strand double crossing over within the inversion and about 8.7% recombination. In(1)sc8/+/Y female produces 19% secondary nondisjunction and 12% recombination (Sturtevant and Beadle, 1936; Grell, 1962, Genetics 47: 1737-54). In(1)sc8/0 partially male lethal (Baker, 1971; Johnson, Harger and Holm, 1979); variegates for y; ac enhanced.
 
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Bloomington
Kyoto
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Discoverer
Sidorov, 1929.
 
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hide Other Comments
"position-effect variegation for: l(1)1Ac" was stated as tentative.
 
hide Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym
In(1)sc8
 
Name Synonym
Secondary FlyBase IDs
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