Aberration Dmel\In(1)sc⁹

General Information
Symbol	Dmel\In(1)sc⁹	Species	D. melanogaster
Name		FlyBase ID	FBab0004208
Feature type	chromosomal_inversion

Computed Breakpoints include	1B3;18B8-18B9
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_inversion (Lindsley and Grell, 1968)
Breakpoints	1B2-1B3;18B8-18B9 (Lindsley and Grell, 1968)
Causes alleles	sc⁹ (Campuzano et al., 1985, Campuzano and Modolell, 1992, Lindsley and Zimm, 1992, Gomez-Skarmeta et al., 1995)
Carries alleles
Transposon Insertions
Formalized genetic data	l(1)sc << bk1 << pcl << coc << bk2 << car
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Campuzano et al., 1985, Ruiz-Gomez and Ghysen, 1993, Carramolino et al., 1982) Breakpoint between DNA coordinates +5.6 and +4.7 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scβ segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).
Comments on Cytology
	Left break irreconcilable with Muller's genetic evidence (FBrf0003098) that the left break of In(1)sc⁹ is to the right of that of In(1)sc⁴. (Lindsley and Grell, 1968) Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from polytene analysis (FBrf0042024) Limits of break 2 from polytene analysis (FBrf0042024)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	sc (Campuzano et al., 1985, Campuzano and Modolell, 1992)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygous females show an almost complete loss of tergite chaetae. (Mari-Beffa et al., 1991)
Stocks ( 2 )
Kyoto	102028 In(1)sc⁹, sc⁹ w^a f¹ Bx¹ 102035 In(1)sc⁹, sc⁹ w^a sn³ f¹ Bx¹ / C(1)DX, y¹ (f¹)
Notes on Origin
Discoverer	Levit, 1929.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	In(1)sc9 In(1)sc⁹ sc⁹ (Mari-Beffa et al., 1991)
Name Synonym
Secondary FlyBase IDs

References ( 14 )
Research paper	Gomez-Skarmeta et al., 1995, Genes Dev. 9(15): 1869--1882 Cis-regulation of achaete and scute: shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs. [FBrf0083155] Martin-Bermudo et al., 1993, Development 118(3): 1003--1112 Molecular characterization of the lethal of scute genetic function. [FBrf0066962] Ruiz-Gomez and Ghysen, 1993, EMBO J. 12(3): 1121--1130 The expression and role of a proneural gene, achaete, in the development of the larval nervous system of Drosophila. [FBrf0058134] Mari-Beffa et al., 1991, Rouxs Arch. Dev. Biol. 200(3): 132--142 Genetic and developmental analyses of chaetae pattern formation in Drosophila tergites. [FBrf0055045] Campuzano et al., 1985, Cell 40: 327--338 Molecular genetics of the achaete-scute gene complex of D. melanogaster. [FBrf0042024] Carramolino et al., 1982, EMBO J. 1: 1185--1191 DNA map of mutations at the scute locus of Drosophila melanogaster. [FBrf0037903] Garcia-Bellido, 1979, Genetics 91: 491--520 Genetic analysis of the achaete-scute system of Drosophila melanogaster. [FBrf0033191] Norton and Valencia, 1965, D. I. S. 40: 40 Genetic extent of the deficiencies formed by combining the left end of In(1)y with the right end of In(1)sc⁹. [FBrf0016803] Muller, 1935, Genetica 17: 237--252 The origination of chromatin deficiencies as minute deletions subject to insertion elsewhere. [FBrf0003098] Lewit, 1930, Roux Arch. EntwMech. Organ. 122: 770--783 Untersuchungen uber Treppenallelomorphismus. [FBrf0002049]
Review	Campuzano and Modolell, 1992, Trends Genet. 8(6): 202--208 Patterning of the Drosophila nervous system: the achaete-scute gene complex. [FBrf0057717]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905] Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp Genetic variations of Drosophila melanogaster. [FBrf0020044]

Aberration Dmel\In(1)sc9

Aberration Dmel\In(1)sc⁹