Aberration Dmel\In(1)sc^S1

General Information
Symbol	Dmel\In(1)sc^S1	Species	D. melanogaster
Name	Inversion (1) scute of Sinitskaya	FlyBase ID	FBab0004216
Feature type	chromosomal_inversion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	bk1 hits sc << bb << bk2
Sequence coordinates
Deleted segment
Duplicated segment
Computed Breakpoints include	1B3-1B4;h32
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_inversion (Lindsley and Grell, 1968)
Breakpoints	1B3-1B4;20B-20D1 (Lindsley and Grell, 1968)
Causes alleles	sc^S1 (Campuzano et al., 1985)
Carries alleles
Transposon Insertions
Genetic mapping information
Comments	Breakpoint between DNA coordinates +28.2 and +26.9 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scβ segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92). Breakpoint(s) molecularly mapped (Campuzano et al., 1985, Carramolino et al., 1982)
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0042024) Limits of break 2 from polytene analysis (citation unavailable) Cytology inferred from genetic identity of left break with that of In(1)sc⁴ and right break with that of with In(1)sc⁸. (Lindsley and Grell, 1968)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	sc (Muller et al., 1937)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygous female sterile (Pucket and Snyder, 1973, Genetics 74: s221). In(1)sc^S1/0 almost completely male lethal (Baker, 1971; Pucket and Snyder, 1973), the adult survivors extreme scute and almost immotile, with reduction in rRNA (Nix, 1973). In gynandromorphs, however, In(1)sc^S1/0 cells viable and normal in appearance suggesting that position effect suppression of rRNA is non-autonomous (Pyati, 1976, Genet. Res. 28: 89-91). Homozygous females are sterile. (Durica and Krider, 1978)
Position Effect Variegation Data
Genes subject to PEV	bb (Reuter et al., 1982)
Stocks ( 7 )
Kyoto	102046 In(1)sc^S1, y¹ / C(1)DX, y¹ f¹ 101139 In(1)sc^S1 In(1)S, y^c4 sc^S1 B¹ / sc^C
Bloomington	3756 In(1)sc^S1, In(1)S, sc^S1 B¹/C(1;YS)1, In(1)dl-49, y¹ l(1)ml¹ w¹ f¹ 678 Dp(1;1)Bx^r49k, v¹ f¹ Bx^r49k car¹/In(1)sc^S1, In(1)dl-49, sc^S1 v¹ f¹ B¹ 4917 y² wy¹ l(1)dd4² car¹/In(1)sc^S1, In(1)dl-49, sc^S1 v¹ f¹ B¹/Dp(1;Y)*, y² sc⁺ 3755 In(1)sc^J1, l(1)1Ac¹ y¹ sc^J1 pn¹ t² v¹ f¹ Tu¹ car¹/In(1)sc^S1 In(1)S, y^c4 sc^S1 B¹ 175 y¹ pn¹ w¹ cm¹ ct⁶ sn³ oc¹ ras² v¹ dy¹ g² f¹ os^o car¹ sw¹/In(1)sc^S1, In(1)dl-49, y^c4 sc^S1 v^Of B¹
Notes on Origin
Discoverer	Sinitskaya, March 1934.
	Induced with In(1)S.
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	In(1)sc^s1 (Abramov et al., 2005) In(1)sc^S1 In(1)scS1
Name Synonym	Inversion (1) scute of Sinitskaya
Secondary FlyBase IDs

References ( 25 )

Generate a list of	All references relating to this aberration ( 25 )

List References by type	Research paper ( 18 ) Personal communication to FlyBase ( 1 ) Abstract ( 3 ) FlyBase analysis ( 1 ) Book ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2006 Show research papers ...

Aberration Dmel\In(1)scS1

Aberration Dmel\In(1)sc^S1