|Also Known As||wm4h, In(1)wm4h|
|Computed Breakpoints include||3C2--3;|
|Member of large scale dataset(s)|
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data|
|Genetic mapping information|
|Comments on Cytology|
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Completely deleted / disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
|NOT in combination with other aberrations|
w variegation leads to clones of phenotypically wild-type cells in a mutant background. This phenotype is suppressed by crmsa.
The presence of a single copy of Mow mutation significantly increases the amount of pigment in both males and females, both MowEMS and Mowgamma suppress position effect variegation.
Mottled eye phenotype.
Variegation at the w locus caused by In(1)wm4h is enhanced by Su(var)3-7hs.PCa or Su(var)3-7hs.PCb, even in the absence of heat shock.
Position effect variegation of w is moderately suppressed by mutations of Rm62. Suppression by allele of Rm62 is additive, heteroallelic escapers are more strongly suppressed than heterozygotes.
Males display a variegated eye phenotype, red spots are clones of cells expressing the w gene and white spots are w inactivation due to heterochromatinisation. Males also heterozygous for Trl13C the eye colour is almost white, indicated a more frequent inactivation of the w gene.
Intermediate variegating line. Eyes show strong white mottling with red patches on a white background.
eyes strongly variegated
|Stocks ( 35 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
|Synonyms & Secondary IDs ( 8 )|
(Marhold et al., 2004, Dej et al., 2004, Zraly et al., 2003, Seum et al., 2002, Delattre et al., 2002, Shaffer, 2002.11.14, Jaquet et al., 2002, Seum et al., 2000, Mollaaghababa et al., 2001, Kuhfittig et al., 2001, Frolov et al., 1998, Pak et al., 1997, Bhadra et al., 1997, Cleard et al., 1995, Reuter et al., 1986, Csink et al., 1994, Tschiersch et al., 1994, Reuter et al., 1985, Krauss et al., 2001, Nickel et al., 2005, Qi et al., 2006, Shaffer et al., 2006, Gilbert et al., 2006, Roy et al., 2007, Nikolenko et al., 2005, Jaquet et al., 2006, Wen et al., 2012, Emelyanov et al., 2010, Brandt et al., 2008)
|Secondary FlyBase IDs|
|References ( 84 )|
|Generate a list of|
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|Recent research papers ( 3 )|
|Recent reviews (0)|
|All reviews listed in FlyBase were published before 2011|