Aberration Dmel\In(1)y^3PLsc^8R

General Information
Symbol	Dmel\In(1)y^3PLsc^8R	Species	D. melanogaster
Name	Inversion (1) yellow-3 of Patterson Left scute-8 Right	FlyBase ID	FBab0004283
Feature type	inversion_derived_deficiency_plus_aneuploid
Also Known As	Df(1)y^3PLsc^8R

Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	In(1)sc⁸ (Chia et al., 1986) In(1)y^3P (Chia et al., 1986)
Mutagen	recombination (Chia et al., 1986)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments	Deletes sequences encoding transcripts T5 and T6. Deficient for 25.5kb of DNA from ac-sc region (Campuzano et al., 1985)
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	ac (del Prado and Garcia-Bellido, 1984, Chia et al., 1986, Alonso and Cabrera, 1988, Leyns et al., 1989, Martinez and Modolell, 1991, Ray and Rodrigues, 1994, Gomez-Skarmeta et al., 1995, Skeath and Doe, 1996, Parras et al., 1996, Jimenez and Ish-Horowicz, 1997) sc (Skeath and Doe, 1996, Parras et al., 1996) y (Chia et al., 1986, Alonso and Cabrera, 1988, Leyns et al., 1989, Ray and Rodrigues, 1994)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	anon-1Ba (Alonso and Cabrera, 1988) anon-1Bc (Alonso and Cabrera, 1988) ase (Alonso and Cabrera, 1988, Ray and Rodrigues, 1994) bb Cyp4g1 (Alonso and Cabrera, 1988) l(1)1Ac l(1)sc (Alonso and Cabrera, 1988, Ray and Rodrigues, 1994) pcl (Alonso and Cabrera, 1988) sc (Alonso and Cabrera, 1988, Leyns et al., 1989, Ray and Rodrigues, 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	In(1)y^3PLsc^8R/Dp(1;Y)y⁺ embryos develop MP2 neuroblast normally. (Parras et al., 1996)
NOT in combination with other aberrations	In In(1)y^3PLsc^8R homozygous embryos, a neural precursor forms the position of the MP2 cluster in wild-type 17% of the time. Roughly half of these precursors exhibit MP2-specific traits while the other half exhibit traits characteristic of other neural precursors specification of MP2. (Wheeler et al., 2003) Wing discs lack most sensory organ precursors. (Nolo et al., 2000) The rare posterior supraalar bristles that form in In(1)y^3PLsc^8R flies have normal axonal projections. (Grillenzoni et al., 1998) Homozygous embryos lack the MP2 neuroblast precursor. Scer\GAL4^rho.PL mediated expression of P{UAS-ac} and P{UAS-sc.P} completely restores the development of a genuine MP2 neuroblast, expression of P{UAS-ase.P} and P{UAS-l'sc} partially restores development of a MP2 neuroblast and P{UAS-ato.P} produces a transformation phenotype, dMP2 transform to vMP2 identity. (Parras et al., 1996) Homozygous embryos exhibit a decrease in MP2 formation due to change in MP2 identity, not a block in differentiation. MP2 formation can be rescued by expression of P{ac} or Scer\GAL4^sca-4512 mediated expression of sc^Scer\UAS.cHa, but not rescued by expression of l(1)sc^Scer\UAS.cCa. (Skeath and Doe, 1996) 25% of glia are absent in the adult wing, compared to 50% being absent in the ac,sc double mutant, Df(1)sc10-1. (Giangrande, 1995) Hemizygotes show an extreme ac phenotype with respect to sensory structures on the thorax. Three of the four I-type bristles are absent from the labellum. In addition, a set of 4 or 5 additional bristles are found between the P-type and the lateral L/I-type row. (Ray and Rodrigues, 1994) Medial neuroblast MP2 or row B forms approximately 14% of the time, whereas the lateral neuroblast 3-5 forms less than 50% of the time. (Skeath et al., 1994) Hemizygous males show a very weak loss of tergite chaetae (fourth hemitergite analysed). (Mari-Beffa et al., 1991) Homozygous viable. (Chia et al., 1986) In heterozygous females the deletion acts as a dominant suppressor of h but not of emc. (del Prado and Garcia-Bellido, 1984) Male viable.
Stocks ( 2 )
Kyoto	102082 In(1)y^3PLsc^8R, y^- ac^- 102060 In(1)y^3PLsc^8R, y^- ac^- ; mwh¹ h¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Completely removes ac and the enhancers that drive sc expression. (Skeath and Doe, 1996)
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	Df(1)y^3PLsc^8R (Chu et al., 1998, Skeath and Doe, 1996, Parras et al., 1996, Gomez-Skarmeta et al., 1995, Skeath et al., 1994, Martinez and Modolell, 1991, Martin-Bermudo et al., 1993, Takeuchi et al., 2007) Dfy^3PLsc^8R (Alonso and Cabrera, 1988) In(1)y3P^Lsc8^R In(1)y^3PCsc^8R (Nolo et al., 2000) In(1)y^3PLsc^8R (Mari-Beffa et al., 1991) y3PL-sc8R (Ray and Rodrigues, 1994) y^3PL-sc^8R (Leyns et al., 1989) y^3PLsc^8R (Ohsako et al., 1994)
Name Synonym	Inversion (1) yellow-3 of Patterson Left scute-8 Right
Secondary FlyBase IDs

References ( 24 )

Generate a list of	All references relating to this aberration ( 24 )

List References by type	Research paper ( 23 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...

Aberration Dmel\In(1)y3PLsc8R

Aberration Dmel\In(1)y^3PLsc^8R