Aberration Dmel\In(2R)nec-e3

General Information
Symbol	Dmel\In(2R)nec-e3	Species	D. melanogaster
Name		FlyBase ID	FBab0004357
Feature type	chromosomal_inversion

Computed Breakpoints include	41;43A1-43A2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	ethyl methanesulfonate (Heitzler et al., 1993, Roote, 1995.9.26)
Class of aberration (relative to progenitor)	chromosomal_inversion (Heitzler et al., 1993, Roote, 1995.9.26, Gubb et al., 1999)
Breakpoints	41;43A1-43A2 (Heitzler et al., 1993, Roote, 1995.9.26) h38R-h46;43A1-43A2 (Gubb et al., 1999)
Causes alleles	pk³ (Gubb et al., 1999, Heitzler et al., 1993, Roote, 1995.9.26)
Carries alleles
Transposon Insertions
Formalized genetic data	bk2 hits pk
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0058613) Left limit of break 2 from complementation mapping against pk (FBrf0058613) Right limit of break 2 from polytene analysis (FBrf0058613)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	nec (Gubb et al., 1999) pk (Gubb et al., 1999, Roote, 1995.9.26)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homoygotes have a slightly necrotic phenotype. Viability on eclosion, heterozygous with a deletion, is higher than nec amorphic mutations. (Heitzler et al., 1993)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	In(2R)nec3 (Roote, 1995.9.26) In(2R)nec³ (Heitzler et al., 1993) In(2R)nec³ pk³ (Gubb et al., 1999) In(2R)nec-e3
Name Synonym
Secondary FlyBase IDs
	FBal0028458
References ( 4 )
Research paper	Gubb et al., 1999, Genes Dev. 13(17): 2315--2327 The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs. [FBrf0111378] Heitzler et al., 1993, Genetics 135(1): 105--115 Genetic and cytogenetic analysis of the 43A-E region containing the segment polarity gene costa and the cellular polarity genes prickle and spiny-legs in Drosophila melanogaster. [FBrf0058613]
Personal communication to FlyBase	Roote, 1995.9.26, 43 lethals. 43 lethals. [FBrf0086245]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]