|Name||Inversion (2L) t||FlyBase ID||FBab0004696|
|Also Known As||In(2L)B|
|Computed Breakpoints include||22D3-22D6;34A8-34A9|
|Member of large scale dataset(s)|
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data||Su(S) << bk1 << Gpdh << Mdh1 << bk2|
|Genetic mapping information|
|Comments on Cytology|
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
|NOT in combination with other aberrations|
The mortality of In(2L)t heterokaryotypes is significantly lower than that of In(2L)t homokaryotypes in males raised at 33oC for 4 days. Both In(2L)t hetero- and homokaryotypes have significantly lower mortality than Standard homokaryotypes in males raised at 33oC for 4 days. In(2L)t heterokaryotypes have a significantly higher mating rate than In(2L)t homokaryotypes after 2 days at 33oC followed by a 4 day recovery at 25oC. The fertility of In(2L)t hetero- and homokaryotypes is higher than that of Standard homokaryotypes after high temperature treatment.
|Stocks ( 25 )|
|Notes on Origin|
Bridges, 30th Jan. 1921.
Reported for an Indian population.
Recovered as: Cosmopolitan inversion.
Isolation: Koleika, Greece.
|Balancer / Genotype Variants of the Aberration|
Naturally occurring inversions have been categorised into classes according to their geographical distribution and frequencies, In(2L)t belongs to the common Cosmopolitan class.
In(2L)t increases the rate of recombination at the base of the X chromosome, but does not affect the rate of recombination at the tip of the X chromosome.
Degree of P factor activity has been tested in flies carrying In(2L)t.
Distribution of polymorphisms at Adh and Gpdh, and for In(2L)t have been studied in populations from the Republic of Panama. In(2L)t was always found to be associated with AdhS GpdhF allele combination.
Common cosmopolitan inversion. The distribution of this inversion in two populations from Valencia, Spain (one from a cellar and one from a vineyard) has been studied.
Common cosmopolitan inversion found in many Indian populations.
In(2L)t frequency in populations decreases with increasing latitude. In(2L)t is nearly always associated with AdhS and GpdhF alleles (Inoue, Ann. Rep. Nat. Inst. Genet. Jap. 32: 105--106).
Common cosmopolitan inversion (based on Australasian frequencies of distribution).
Common cosmopolitan inversion.
Found in many natural populations (e.g., Warters, 1944, Texas Univ. Publ. 4445: 129-74; Oshima and Watanabe, 1965, D. I. S. 40: 88; Ashburner and Lemeunier, 1976, Proc. R. Soc. London, B 193: 137-57; Pipkin, Franklin-Springer, Law and Lubega, 1976, J. Hered. 67: 258-66; Stalker, 1976, Genetics 82: 323-47; Choi, 1977, D. I. S. 52: 88; Mettler, Voelker and Mukai, 1977, Genetics 87: 169-76; Knibb, 1982, Genetica 58: 213-21). Inversion in N.C. population formerly thought to be In(2L)Cy rather than In(2L)t (Mukai, Mettler and Chigusa, 1971, Proc. Nat. Acad. Sci. USA 68: 1065-69).
|Synonyms & Secondary IDs ( 8 )|
Inversion (2L) t
|Secondary FlyBase IDs|
|References ( 90 )|
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|Recent research papers (0)|
|All research papers listed in FlyBase were published before 2011|
|Recent reviews (0)|
|All reviews listed in FlyBase were published before 2011|