A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Aberration Dmel\In(2L)t

General Information
SymbolDmel\In(2L)tSpeciesD. melanogaster
NameInversion (2L) tFlyBase IDFBab0004696
Feature typechromosomal_inversion
Also Known AsIn(2L)B
Computed Breakpoints include 22D3-22D6;34A8-34A9
Sequence coordinates
Member of large scale dataset(s)
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Description
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FB2013_03
FB2013_02
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hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
natural population
(Das and Singh, 1990, Das and Singh, 1991, Inoue et al., 1994, Knibb et al., 1981, Singh and Das, 1990, Inoue and Igarashi, 1994, Stalker, 1976, Pipkin et al., 1976, Ashburner and Lemeunier, 1976, Choi et al., 1984, Zacharopoulou, 1974, Campos et al., 2000)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Koryakov et al., 1994, Knibb et al., 1981, Singh and Das, 1990, Taberner and Gonzalez, 1991, Zabalou et al., 1994, Stalker, 1976, Pipkin et al., 1976, Ashburner and Lemeunier, 1976, Inoue and Watanabe, 1979, Choi et al., 1984, Zacharopoulou, 1974, Andolfatto et al., 1999)
Breakpoints
22D3-22E1;34A8-34A9
(Ashburner and Lemeunier, 1976, Inoue and Watanabe, 1979, Kamping and van Delden, 1995)
22D-22E;34A
(Stalker, 1976)
22D;34A
(Zacharopoulou, 1974, Knibb et al., 1981, Singh and Das, 1990, Taberner and Gonzalez, 1991, Choi et al., 1984, Zabalou et al., 1994)
22E;33F
(Koryakov et al., 1994)
23A;33E
(Pipkin et al., 1976)
[];[];34A8--9
(Andolfatto et al., 1999)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data Su(S) << bk1 << Gpdh << Mdh1 << bk2
Genetic mapping information
Comments
hide Comments on Cytology
Left limit of break 1 from polytene analysis (FBrf0029349) Right limit of break 1 from polytene analysis (FBrf0026036) Limits of break 2 from polytene analysis (FBrf0029349)
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AF172291
 
AF172292
 
AF172293
 
AF172294
 
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AF217926
 
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AF217928
 
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AF217949
 
AF275819
 
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AF275824
 
AF275825
 
AF275826
 
AF275827
 
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hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Molecular Data
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Complementation Data
Molecular Data
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Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
The mortality of In(2L)t heterokaryotypes is significantly lower than that of In(2L)t homokaryotypes in males raised at 33oC for 4 days. Both In(2L)t hetero- and homokaryotypes have significantly lower mortality than Standard homokaryotypes in males raised at 33oC for 4 days. In(2L)t heterokaryotypes have a significantly higher mating rate than In(2L)t homokaryotypes after 2 days at 33oC followed by a 4 day recovery at 25oC. The fertility of In(2L)t hetero- and homokaryotypes is higher than that of Standard homokaryotypes after high temperature treatment.
(Kamping and van Delden, 1999)
Differences in development time and body weight are found at varying temperatures. Experiments prove that the karyotypes are under selection and the frequency changes can be discussed in relation to the geographic distribution of In(2L)t.
(van Delden and Kamping, 1991)
hide Stocks ( 25 )
Bloomington
419
wgSp-1/In(2L)t, l(2)R1
813
In(2L)t, esc1 c1 sp1/SM5
326
In(2L)t, l(2)a1 bs3/In(2LR)bwV1, ds33k bwV1
6112
Df(2L)nNxF1, b1/In(2L)t, In(2R)Cy, Cy1 amosRoi-1 pr1 cn1
6113
Df(2L)nNxF2, b1/In(2L)t, In(2R)Cy, Cy1 amosRoi-1 pr1 cn1
6232
In(1)wm4h; Su(var)2-11/In(2L)t, In(2R)Cy, Cy1 amosRoi-1 pr1 cn1
Kyoto
106085
In(2L)t, esc1 c1 sp1/SM5
108612
Df(2L)nNxF1, b1/In(2L)t, In(2R)Cy, Cy1 amosRoi-1 pr1 cn1
108613
Df(2L)nNxF2, b1/In(2L)t, In(2R)Cy, Cy1 amosRoi-1 pr1 cn1
101820
In(1)wm4h ; In(2L)t In(2R)Cy, Cy1 amosRoi-1 pr1 cn1 / snaSco
101304
b1 elA2 AdhF / In(2L)t In(2R)Cy, Cy1 amosRoi-1 pr1 cn1
108691
In(1)wm4h; Su(var)2-11/In(2L)t, In(2R)Cy, Cy1 amosRoi-1 pr1 cn1
hide Notes on Origin
Discoverer
Bridges, 30th Jan. 1921.
 
Reported for an Indian population.
(Das and Singh, 1990)
Cosmopolitan inversion.
(Pipkin et al., 1976)
Recovered as: Cosmopolitan inversion.
(Stalker, 1976)
Isolation: Koleika, Greece.
(Zacharopoulou, 1974)
hide Balancer / Genotype Variants of the Aberration
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Naturally occurring inversions have been categorised into classes according to their geographical distribution and frequencies, In(2L)t belongs to the common Cosmopolitan class.
(Inoue et al., 1994)
In(2L)t increases the rate of recombination at the base of the X chromosome, but does not affect the rate of recombination at the tip of the X chromosome.
(Sniegowski et al., 1994)
Degree of P factor activity has been tested in flies carrying In(2L)t.
(Kim, 1993)
Distribution of polymorphisms at Adh and Gpdh, and for In(2L)t have been studied in populations from the Republic of Panama. In(2L)t was always found to be associated with AdhS GpdhF allele combination.
(van't Land et al., 1993)
Common cosmopolitan inversion. The distribution of this inversion in two populations from Valencia, Spain (one from a cellar and one from a vineyard) has been studied.
(Taberner and Gonzalez, 1991)
Cosmopolitan inversion.
(Villar et al., 1991)
Common cosmopolitan inversion found in many Indian populations.
(Singh and Das, 1990, Das and Singh, 1991)
In(2L)t frequency in populations decreases with increasing latitude. In(2L)t is nearly always associated with AdhS and GpdhF alleles (Inoue, Ann. Rep. Nat. Inst. Genet. Jap. 32: 105--106).
(van Delden and Kamping, 1989)
Common cosmopolitan inversion (based on Australasian frequencies of distribution).
(Knibb et al., 1981)
Common cosmopolitan inversion.
(Zacharopoulou and Pelecanos, 1980, Das and Singh, 1991, Inoue and Igarashi, 1994)
Significant linkage disequilibrium has been detected between In(2L)t and Adh.
(Mukai and Voelker, 1977)
Found in many natural populations (e.g., Warters, 1944, Texas Univ. Publ. 4445: 129-74; Oshima and Watanabe, 1965, D. I. S. 40: 88; Ashburner and Lemeunier, 1976, Proc. R. Soc. London, B 193: 137-57; Pipkin, Franklin-Springer, Law and Lubega, 1976, J. Hered. 67: 258-66; Stalker, 1976, Genetics 82: 323-47; Choi, 1977, D. I. S. 52: 88; Mettler, Voelker and Mukai, 1977, Genetics 87: 169-76; Knibb, 1982, Genetica 58: 213-21). Inversion in N.C. population formerly thought to be In(2L)Cy rather than In(2L)t (Mukai, Mettler and Chigusa, 1971, Proc. Nat. Acad. Sci. USA 68: 1065-69).
 
hide Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym
2Lt
(Inoue et al., 1994)
(2L)t
(Caceres et al., 1999)
In(2L)22D;34A
(Campos et al., 2000)
In(2L)B
(Stalker, 1976, Kamping and van Delden, 1994, Oshima and Watanabe, 1965)
In(2L)C
(Mukai et al., 1970)
In(2L)t
(Turner et al., 2008, Levine and Begun, 2008, Zurovcova et al., 2006, Aguadé, 2009, Presgraves et al., 2009)
unnamed
(Zacharopoulou, 1974)
Name Synonym
Inversion (2L) t
 
Secondary FlyBase IDs
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