A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Aberration Dmel\In(2LR)Gla

General Information
SymbolDmel\In(2LR)GlaSpeciesD. melanogaster
NameInversion (2LR) GlazedFlyBase IDFBab0004765
Feature typechromosomal_inversionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data bk1 hits wg
Sequence coordinates
Deleted segment
Duplicated segment
Computed Breakpoints include 27D;51E
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
2Lt - 22D3 | 34A8 - 27D | 51E - 34A9 | 22E1 - 27D | 51E - 2Rt
 
Progenitor
In(2L)t
 
Mutagen
X ray
 
Class of aberration (relative to progenitor)
chromosomal_inversion
 
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
Limits of break 1 from complementation mapping against Gla (citation unavailable) Limits of break 2 from polytene analysis (citation unavailable)
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Recessive lethal. Effective crossover suppressor; no single or double crossovers recovered to the left of P{wEcol\lexA.240}c (Alexander, 1952, Texas Univ. Publ. 5204: 219-26). Orange Malpighian tubules in larvae and adults heterozygous with cn (Ashburner).
 
The recessive lethality of the In(2LR)Gla chromosome is probably due to the inversion breakpoints.
(Brunner et al., 1999)
hide Position Effect Variegation Data
  
hide Stocks ( 101 )
Szeged
-
Df(2L)ED1466/In(2LR)Gla
Bloomington
1951
U2/In(2LR)Gla, wgGla-1
8884
Df(2R)nap11/In(2LR)Gla, wgGla-1
1006
Df(2R)nap1/Dp(2;2)BG, In(2LR)Gla, wgGla-1
1007
Df(2R)nap9/Dp(2;2)BG, In(2LR)Gla, wgGla-1
6648
Df(2L)dppd14/In(2LR)Gla, wgGla-1
Kyoto
106599
U2/In(2LR)Gla, wgGla-1
106403
Df(2R)bwVDe2LPxKR/In(2LR)Gla
102053
T(1;2)scS2, pwn1 / In(2LR)Gla
101516
In(2L)wgP / In(2LR)Gla, wgGla-1
101528
In(2LR)Gla, wgGla-1 / wgl-14+RC3
106164
Df(2R)nap1/In(2LR)Gla, Dp(2;2)BG, wgGla-1
hide Notes on Origin
Discoverer
Associated with: wgGla-1.
 
hide Balancer / Genotype Variants of the Aberration
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    hide Other Comments
    hide Synonyms & Secondary IDs ( 4 )
    Reported As
    Symbol Synonym
    Gla
    (Bloomington Drosophila Stock Center, 2004.7.26)
    In(2LR)Gla
    (Collett, 2008.2.16)
    In(2LR)GlaBcElp
    (Dong et al., 1997)
    Name Synonym
    Inversion (2LR) Glazed
     
    Secondary FlyBase IDs
      hide References ( 17 )
      Research paper
      Mackay et al., 2005, Genetics 170(4): 1723--1735
      Polygenic Mutation in Drosophila melanogaster: mapping Spontaneous Mutations Affecting Sensory Bristle Number. [FBrf0187648]
      Jhaveri et al., 2004, Development 131(9): 1903--1912
      Positioning sensory terminals in the olfactory lobe of Drosophila by Robo signaling. [FBrf0174568]
      Cox et al., 2000, Genetics 155(4): 1725--1740
      A screen for mutations that suppress the phenotype of Drosophila armadillo, the beta-catenin homolog. [FBrf0129777]
      Brunner et al., 1999, Dev. Biol. 206(2): 178--188
      The dominant mutation glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. [FBrf0106272]
      Dong et al., 1997, Genes Dev. 11(1): 94--105
      Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A. [FBrf0091048]
      Roote et al., 1996, D. I. S. 77: 55--65
      Aberrations in the l(2)34Fc - l(2)35Bb region of chromosome arm 2L. [FBrf0091422]
      Pauli et al., 1995, D. I. S. 76: 107--124
      Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455]
      Castrillon and Wasserman, 1994, Development 120(12): 3367--3377
      diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. [FBrf0075099]
      Taylor and Truman, 1992, Development 114: 625--642
      Commitment of abdominal neuroblasts in Drosophila to a male or female fate is dependent on genes of the sex-determining hierarchy. [FBrf0055884]
      Hutter, 1990, Genet. Res. 55: 159--164
      'Exceptional sons' from Drosophila melanogaster mothers carrying a balancer X chromosome. [FBrf0051871]
      Gubb et al., 1988, Genetics 119: 377--390
      A selective screen to recover chromosomal deletions and duplications in Drosophila melanogaster. [FBrf0048206]
      Ashburner et al., 1983, Genetics 104: 405--431
      The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0039455]
      Alexander, 1952, Univ. Texas Publs 5204: 219--226
      The effect of two pericentric inversions upon crossing over in Drosophila melanogaster. [FBrf0008799]
      Personal communication to FlyBase
      Collett, 2008.2.16, Dipeptidase-A and CG17337.
      Dipeptidase-A and CG17337. [FBrf0203178]
      Bloomington Drosophila Stock Center, 2004.7.26, In(2LR)Gla.
      In(2LR)Gla. [FBrf0178902]
      FlyBase analysis
      FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type.
      En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
      Book
      Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
      The Genome of Drosophila melanogaster. [FBrf0066905]