|Name||Inversion (2R) brown-Variegated||FlyBase ID||FBab0005115|
|Also Known As||bwVDe2, bwV|
|Computed Breakpoints include||h42-h43;59E1|
|Member of large scale dataset(s)|
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data||l(2)41Aa << bk1 << msf << bw << bk2 << mi|
|Genetic mapping information|
|Comments on Cytology|
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
The bw+ cis-effect in different inversion chromosomes is ranked: In(2R)bwVDe1 > In(2R)bwVDe2 > In(2R)bwVK.
Position effect variegation (PEV) at the bw locus caused by In(2R)bwVDe2 is dominantly enhanced by Dp(2;2)Mdh, and suppressed by Df(2R)en-A.
The position effect variegation at the bw locus caused by In(2R)bwVDe2 is suppressed by Df(3R)Ace-HD1.
The position effect variegation of bw caused by In(2R)bwVDe2 is consistently suppressed by T(2;3)SbV, although In(2R)bwVDe2 has little effect on the position effect variegation of Sb caused by T(2;3)SbV. In(2R)bwVDe2 and C(1;YL)wmMc, and In(2R)bwVDe2 and In(1)wm51b in combination show dominant suppression of variegation of one or both of w and bw, as measured by eye pigment levels. In contrast In(2R)bwVDe2 and T(1;4)wmJ in combination show enhancement of variegation of one or both of w and bw.
|NOT in combination with other aberrations|
Carnitine compounds (L-Carnitine, L-Acetylcarnitine and L-Propionylcarnitine) show a significant suppression on bw variegation. Butyrate gives a weaker suppression.
homozygous lethal in embryonic stage <up>e.g., In(2R)bwDe2 (Tsai, 1955, Genetics 40: 601)</up>. Eye color mosaic of brown and dark brown patches.
|Stocks ( 3 )|
|Notes on Origin|
Demerec, 14th Oct. 1933.
|Balancer / Genotype Variants of the Aberration|
Choi, 1977, D. I. S. 52: 88; Mettler, Voelker and Mukai, 1977,
|Synonyms & Secondary IDs ( 6 )|
Inversion (2R) brown-Variegated
|Secondary FlyBase IDs|
|References ( 22 )|
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|Recent research papers (0)|
|All research papers listed in FlyBase were published before 2011|