FlyBase Aberration Report: Dmel\In(2R)bw[VDe2]

General Information

Symbol

In(2R)bw^VDe2

Species

D. melanogaster

Name

Inversion (2R) brown-Variegated

FlyBase ID

FBab0005115

Feature type

chromosomal_inversion

Also Known As

bw^VDe2, bw^V

Computed Breakpoints include

h42-h43;59E1

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

Class of aberration (relative to wild type)

chromosomal_inversion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_inversion

(Cleard et al., 1997, Koryakov et al., 1996)

Breakpoints

h42-h43;59D1-59E2

(Koryakov et al., 1996)

41A-41B;59D6-59E1

(Cleard et al., 1997)

Causes alleles

bw^VDe2

(Belyaeva et al., 1997)

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)41Aa << bk1 << msf << bw << bk2 << mi

Genetic mapping information

Comments

Comments on Cytology

Ref: FBrf0066905.

(Cleard et al., 1997)

Ref: FBrf0003816 and FBrf0054171.

(Koryakov et al., 1996)

Limits of break 1 from polytene analysis (FBrf0092594) Left limit of break 2 from complementation mapping against bw (citation unavailable) Right limit of break 2 from polytene analysis (FBrf0098579)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Related Comments

Phenotypic Data

In combination with other aberrations

The In(2R)bw^VDe2 pigmentation phenotype is suppressed by C(1;YL)w^mMc or In(1)w^m51b.

(Talbert and Henikoff, 2000)

The bw⁺ cis-effect in different inversion chromosomes is ranked: In(2R)bw^VDe1 > In(2R)bw^VDe2 > In(2R)bw^VK.

(Koryakov et al., 1998)

Position effect variegation (PEV) at the bw locus caused by In(2R)bw^VDe2 is dominantly enhanced by Dp(2;2)Mdh, and suppressed by Df(2R)en-A.

(Sinclair et al., 1998)

The position effect variegation at the bw locus caused by In(2R)bw^VDe2 is suppressed by Df(3R)Ace-HD1.

(Cleard et al., 1997)

The position effect variegation of bw caused by In(2R)bw^VDe2 is consistently suppressed by T(2;3)Sb^V, although In(2R)bw^VDe2 has little effect on the position effect variegation of Sb caused by T(2;3)Sb^V. In(2R)bw^VDe2 and C(1;YL)w^mMc, and In(2R)bw^VDe2 and In(1)w^m51b in combination show dominant suppression of variegation of one or both of w and bw, as measured by eye pigment levels. In contrast In(2R)bw^VDe2 and T(1;4)w^mJ in combination show enhancement of variegation of one or both of w and bw.

(Lloyd et al., 1997)

NOT in combination with other aberrations

Homozygous lethal.

(Koryakov et al., 1998)

Carnitine compounds (L-Carnitine, L-Acetylcarnitine and L-Propionylcarnitine) show a significant suppression on bw variegation. Butyrate gives a weaker suppression.

(Fanti et al., 1994)

homozygous lethal in embryonic stage <up>e.g., In(2R)bw^De2 (Tsai, 1955, Genetics 40: 601)</up>. Eye color mosaic of brown and dark brown patches.

Stocks (3)

Bloomington

1582

In(2LR)Gla, wg^Gla-1 PPO1^Bc/In(2R)bw^VDe2, bw^VDe2

Kyoto

101529

In(2R)bw^VDe2, bw^VDe2 / In(2LR)Rev

106401

In(2LR)Gla, wg^Gla-1 PPO1^Bc/In(2R)bw^VDe2, bw^VDe2

Notes on Origin