Aberration Dmel\T(1;3)sc^J4

General Information
Symbol	Dmel\T(1;3)sc^J4	Species	D. melanogaster
Name	Translocation (1;3) scute of Jacobs-Muller	FlyBase ID	FBab0006465
Feature type	deficient_translocation

Computed Breakpoints include	1B2-1B14;3A3;61A
Deleted segment	1B2--3A3
Sequence coordinates
Recent Updates
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FB2012_01
FB2011_10
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	deficient_translocation (Lindsley and Grell, 1968, Smith et al., 1993)
Breakpoints	1B;3A3-3C2;61A (Lindsley and Grell, 1968) 1B;3A3;[] (Smith et al., 1993, Harbecke and Lengyel, 1995, Min and Benzer, 1997)
Causes alleles	sc^J4 (Lindsley and Zimm, 1992)
Carries alleles
Transposon Insertions
Formalized genetic data	sc << bk1 << z << bk2 << gt << bk3
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Campuzano et al., 1985)
Comments on Cytology
	Cytology inferred from genetic tests. (Lindsley and Grell, 1968) Left limit of break 1 from complementation mapping against ac (citation unavailable) Right limit of break 1 from polytene analysis (FBrf0042024) Limits of break 2 from polytene analysis (FBrf0065574) Limits of break 3 from polytene analysis (FBrf0042024)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	arm (Harbecke and Lengyel, 1995) gt (Harbecke and Lengyel, 1995) prage (Tadros et al., 2003)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	spongecake (Min and Benzer, 1997)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	T(1;3)sc^J4/In(1)sc^V2/0 male viable (Baker, 1971, Proc. Nat. Acad. Sci. USA 68: 2472-76).
NOT in combination with other aberrations	Deficient embryos show an uninterpretable mutant midgut phenotype. (Bilder and Scott, 1995) Homozygous embryos are very abnormal compared to wild-type. (Harbecke and Lengyel, 1995) No neural tissue. (Smith et al., 1993)
Stocks ( 1 )
Kyoto	106714 T(1;3)sc^J4, sc^J4/C(1)DX, y¹ f¹; Dp(1;f)z9
Notes on Origin
Discoverer	Jacobs-Muller.

Balancer / Genotype Variants of the Aberration

Separable Components
	Df(1)sc-J4 Dp(1;3)sc^J4
Other Comments
	Endoreplication normal. (Smith et al., 1993)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(1)sc^J4 (Min and Benzer, 1997, Bilder and Scott, 1995) Df(1)sc-J4 (Tadros et al., 2003, Li and Li, 2003, Secombe et al., 2007) Df(1)scJ4 (Harbecke and Lengyel, 1995) T(1;3)sc^J4 T(1;3)sc-J4
Name Synonym	Translocation (1;3) scute of Jacobs-Muller
Secondary FlyBase IDs

References ( 16 )
Research paper	Secombe et al., 2007, Genes Dev. 21(5): 537--551 The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. [FBrf0193047] Li and Li, 2003, Genetics 164(1): 247--258 Drosophila gain-of-function mutant RTK Torso triggers ectopic Dpp and STAT signaling. [FBrf0158996] Tadros et al., 2003, Genetics 164(3): 989--1001 Regulation of maternal transcript destabilization during egg activation in Drosophila. [FBrf0160993] Min and Benzer, 1997, Curr. Biol. 7(11): 885--888 Spongecake and eggroll: two hereditary diseases in Drosophila resemble patterns of human brain degeneration. [FBrf0099402] Bilder and Scott, 1995, Genetics 141(3): 1087--1100 Genomic regions required for morphogenesis of the Drosophila embryonic midgut. [FBrf0083777] Harbecke and Lengyel, 1995, Roux Arch. dev. Biol. 204(5): 308--329 Genes controlling posterior gut development in the Drosophila embryo. [FBrf0082073] Smith et al., 1993, Genetics 135(3): 817--829 Identification of genomic regions required for DNA replication during Drosophila embryogenesis. [FBrf0065574] Campuzano et al., 1985, Cell 40: 327--338 Molecular genetics of the achaete-scute gene complex of D. melanogaster. [FBrf0042024] Smith et al., 1985, Genetics 110: 647--670 Mutations in genes encoding essential mitotic functions in Drosophila melanogaster. [FBrf0042650] Baker, 1971, Proc. Natl. Acad. Sci. USA 68(10): 2472--2476 Evidence for position-effect suppression of the ribosomal RNA cistrons in Drosophila melanogaster. [FBrf0023145] Tokunaga, 1969, D. I. S. 44: 49 [New mutants report.] [FBrf0096431] Muller, 1934, D. I. S. 2: 60 Extension of third chromosome. [FBrf0063732] Muller, 1932, Int. Congr. Genet. 6 1: 213--255 Further studies on the nature and causes of gene mutations. [FBrf0002371]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905] Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp Genetic variations of Drosophila melanogaster. [FBrf0020044]

Aberration Dmel\T(1;3)scJ4

Aberration Dmel\T(1;3)sc^J4