A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\T(1;4)BS

General Information
SymbolDmel\T(1;4)BSSpeciesD. melanogaster
NameTranslocation (1;4) Bar of StoneFlyBase IDFBab0006529
Feature typechromosomal_translocationCreated / Updated2006-08-22/2006-08-22
Formalized genetic data bk1 hits B
Sequence coordinates
Deleted segment
Duplicated segment
Computed Breakpoints include 16A1;16A7-16B1;102F
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
1Lt - 16A7 | 102F - 4Lt ; 1Rt - 16A1 | 16A7 | 102F - 4Rt
 
Progenitor
Dp(1;1)B
 
Mutagen
X ray
 
Class of aberration (relative to progenitor)
chromosomal_translocation
(McKee, 1987)
Breakpoints
16A;4Lt-4Rt
(McKee, 1987)
Causes alleles
BS
 
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Breakpoint(s) molecularly mapped
(Tsubota et al., 1989)
Southern blots and in situ hybridization mapped the T(1;4)BS breakpoint 15 kb distal of the Dp(1;1)B breakpoint.
(Norris et al., 1992)
hide Comments on Cytology
Left limit of break 1 from complementation mapping against B (citation unavailable) Right limit of break 1 from polytene analysis (citation unavailable) Limits of break 2 from polytene analysis (citation unavailable) Limits of break 3 from polytene analysis (citation unavailable)
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Position-effect at B more extreme than in Dp(1;1)B. Homozygous female viable homozygous female fertile. Male viable but with reduced fertility (Novitski, 1970).
 
hide Position Effect Variegation Data
Genes subject to PEV
B
(Lindsley and Zimm, 1992)
hide Stocks ( 5 )
Bloomington
4058
C(1)DX, y1 w1 f1; T(1;4)BS, BS
4352
T(1;4)BS, BS car1/C(1)DX, y1 f1
1301
T(1;4)BS, y2 cv1 v1 BS car1
4476
Dp(1;YL)scS1; C(1;YS)1, T(1;4)BS, BS/C(1)DX, y1 w1 f1
4060
In(1)sc8LR(1)2R, Dp(1;1)BSTMG, f1 BS; T(1;4)BS, C(1;Y)6, BS
hide Notes on Origin
Discoverer
Stone, 1931.
 
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
    hide Other Comments
    Used by Stern in cytological demonstration of crossing over (1931, Biol. Zentr. 51: 547-87). XP4D from T(1;4)BS used by Lindsley and Sandler [1963, Methodology in Basic Genetics (W. J. Burdette, ed.). Holden-Day, Inc., pp. 390-403] in construction of compound-generating BS duplications. Reciprocal products of meiosis in male not recovered with equal frequencies (Novitski and Sandler, 1957, Proc. Nat. Acad. Sci. USA 43: 318-24; Zimmering, 1960, Genetics 45: 1253-68; Zimmering and Barbour, 1961, Genetics 46: 1253-60; Zimmering and Perlman, 1962, Can. J. Genet. Cytol. 4: 333-36; Novitski, 1970, D. I. S. 45: 87).
     
    T(1;4)BS substantially reduces recovery of independently assorting autosomal free duplication: chromosome shows meiotic drive. The effect of chromosome pairing sites on meiotic drive by T(1;4)BS is linked to the Ts(1Lt;4Lt)BS segregant.
    (McKee, 1987)
    hide Synonyms & Secondary IDs ( 6 )
    Reported As
    Symbol Synonym
    T(1;4)1
     
    T(1;4)4
     
    T(1;4)A4
     
    T(1;4)BS
     
    XP4D,T(1;4)BS
    (Agudo et al., 2000)
    Name Synonym
    Translocation (1;4) Bar of Stone
     
    Secondary FlyBase IDs
      hide References ( 19 )
      Research paper
      Agudo et al., 2000, Chromosoma 109(3): 190--196
      A dicentric chromosome of Drosophila melanogaster showing alternate centromere inactivation. [FBrf0128883]
      Sawamura and Yamamoto, 1993, Molec. gen. Genet. 239(3): 441--449
      Cytogenetical localization of Zygotic hybrid rescue (Zhr), a Drosophila melanogaster gene that rescues interspecific hybrids from embryonic lethality. [FBrf0059084]
      Norris et al., 1992, Molec. gen. Genet. 233: 106--112
      The identification of the B<up>S</up> breakpoint and of two possible Bar genes. [FBrf0057261]
      Ferrus et al., 1990, Genetics 125: 383--398
      Genetic analysis of the Shaker gene complex of Drosophila melanogaster. [FBrf0051942]
      Tsubota et al., 1989, Genetics 122: 881--890
      The cloning of the Bar region and the B breakpoint in Drosophila melanogaster: evidence for a transposon-induced rearrangement. [FBrf0049945]
      McKee, 1987, Genetics 116: 409--413
      X;4 translocations and meiotic drive in Drosophila melanogaster males: Role of sex chromosome pairing. [FBrf0046374]
      Thomas and Wyman, 1984, J. Neurosci. 4: 530--538
      Mutations altering synaptic connectivity between identified neurons in Drosophila. [FBrf0041358]
      Childress and Hartl, 1972, Genetics 71(3): 417--427
      Sperm preference in Drosophila melanogaster. [FBrf0023948]
      Novitski, 1970, D. I. S. 45: 87--88
      The concept of gamete dysfunction. [FBrf0021389]
      Zimmering and Perlman, 1962, Canad. J. Genet. Cytol. 4: 333--336
      Modification of abnormal gametic ratios in Drosophila. [FBrf0014422]
      Zimmering and Barbour, 1961, Genetics 46: 1253--1260
      Modification of abnormal gametic ratios in Drosophila. [FBrf0013898]
      Zimmering, 1960, Genetics 45: 1253--1268
      Modification of abnormal gametic ratios in Drosophila. [FBrf0013310]
      Novitski and Sandler, 1957, Proc. Natl. Acad. Sci. USA 43(4): 318--324
      Are all products of spermatogenesis regularly functional? [FBrf0011547]
      Stone, 1934, Genetica 16: 506--519
      Linkage between the X and IV chromosomes in Drosophila melanogaster. [FBrf0002771]
      Stern, 1931, Biol. Zentbl. 51: 547--587
      Zytologisch-genetische Untersuchungen als Beweise fur die Morgansche Theorie des Faktorenaustauschs. [FBrf0002175]
      Review
      McKee, 1991, Am. Nat. 137(3): 332--339
      X-Y pairing, meiotic drive, and ribosomal DNA in Drosophila melanogaster males. [FBrf0053143]
      Personal communication to FlyBase
      Green, 2002.2.24, Dp(1;1)MMG.
      Dp(1;1)MMG. [FBrf0145641]
      FlyBase analysis
      FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type.
      En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
      Book
      Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
      The Genome of Drosophila melanogaster. [FBrf0066905]