Aberration Dmel\T(2;3)ap^Xa

General Information
Symbol	Dmel\T(2;3)ap^Xa	Species	D. melanogaster
Name	Translocation (2;3) apterous-Xasta	FlyBase ID	FBab0007867
Feature type	chromosomal_translocation

Computed Breakpoints include	41F9-41F11;89E8-89F1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order	2Lt - 41F \| 89E8 - 89C3 \| 96A19 - 3Rt ; 2Rt - 58B1 \| 42A3 - 58A4 \| 42A2 - 41F \| 89F1 - 96A18 \| 89C2 - 3Lt (Lewis, 1951)
Progenitor	In(2R)Cy In(3R)P
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_translocation
Breakpoints
Causes alleles	ap^Xa (Jack and DeLotto, 1992, Sturtevant, 1934)
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 hits ap
Genetic mapping information
Comments
Comments on Cytology
	Cytology by FBrf0064033 corrected by FBrf0008101. (Lewis, 1951) Limits of break 1 from complementation mapping against ap (citation unavailable) Limits of break 2 from polytene analysis (citation unavailable)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	DNaseII (Evans et al., 2002)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygote virtually lethal.
Stocks ( 42 )
Bloomington	3141 T(2;3)ap^Xa, ap^Xa/SM5 561 Pw¹/T(2;3)ap^Xa, ap^Xa 4252 NX¹/T(2;3)ap^Xa, ap^Xa 3419 Ubx^bx-3/T(2;3)ap^Xa, ap^Xa 3433 Ubx^Cbx-1/T(2;3)ap^Xa, ap^Xa 3449 Ubx^pbx-1/T(2;3)ap^Xa, ap^Xa 4067 T(2;3)ap^Xa, ap^Xa/l(3)XaR¹ 1788 T(2;3)ap^Xa, ap^Xa/TM6B, Tb¹ 3192 w^*; T(2;3)ap^Xa, ap^Xa/CyO; TM6 1796 T(2;3)ap^Xa, ap^Xa/SM5; TM3, Sb¹
Kyoto	105957 H²/T(2;3)ap^Xa, ap^Xa 106905 w^*; T(2;3)ap^Xa, ap^Xa/CyO; TM6
	More stocks available...
Notes on Origin
Discoverer	Serebrovsky, Jan. 1928.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The first X-ray-induced mutation recovered in the USSR. Useful as a balancer of 2R and 3R.
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	T(2;3)Ap^Xa (Bornemann et al., 1996) T(2;3)ap^Xa T(2;3)apXa (Bejarano and Busturia, 2004) T(2;3)ap-Xa T(2;3)Xa (Burdick, 1999, )
Name Synonym	Translocation (2;3) apterous-Xasta Translocation(2;3)Xasta
Secondary FlyBase IDs

References ( 14 )
Research paper	Bejarano and Busturia, 2004, Dev. Biol. 268(2): 327--341 Function of the Trithorax-like gene during Drosophila development. [FBrf0174524] Hanyu-Nakamura et al., 2004, Development 131(18): 4545--4553 Germ cell-autonomous Wunen2 is required for germline development in Drosophila embryos. [FBrf0180147] Evans et al., 2002, Gene 295(1): 61--70 Drosophila acid DNase is a homolog of mammalian DNase II. [FBrf0151699] Bornemann et al., 1996, Development 122(5): 1621--1630 The Drosophila Polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein. [FBrf0086923] Jack and DeLotto, 1992, Genetics 131(2): 353--363 Effect of wing scalloping mutations on cut expression and sense organ differentiation in the Drosophila wing margin. [FBrf0056217] Micol and Garcia-Bellido, 1988, Proc. Natl. Acad. Sci. U.S.A. 85: 1146--1150 Genetic analysis of 'transvection' effects involving Contrabithorax mutations in Drosophila melanogaster. [FBrf0048913] Reuter et al., 1983, Biol. Zentbl. 102(3): 281--298 Genetic study of position effect variegation in Drosophila melanogaster: in (1)w^m4 as a standard rearrangement for the isolation and characterization of suppressor and enhancer mutants. [FBrf0038949] Lewis, 1951, D. I. S. 25: 108--109 Additions and corrections to the cytology of rearrangements. [FBrf0008101] Morgan et al., 1936, Yb. Carnegie Instn, Wash. 35: 289--297 Constitution of the germinal material in relation to heredity. [FBrf0064033] Serebrovsky and Dubinin, 1930, J. Hered. 21: 259--265 X-ray experiments with Drosophila. [FBrf0001995]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Teaching note	Burdick, 1999, D. I. S. 82: 128--129 Xasta in class experiments. [FBrf0111818]
Stock list	Sturtevant, 1934, D. I. S. 2: 11--20 Stock list. [FBrf0063892]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Aberration Dmel\T(2;3)apXa

Aberration Dmel\T(2;3)ap^Xa