Aberration Dmel\T(Y;3)B81

General Information
Symbol	Dmel\T(Y;3)B81	Species	D. melanogaster
Name		FlyBase ID	FBab0008884
Feature type	chromosomal_translocation
Also Known As	Df(3R)B81

Computed Breakpoints include	h1-h17;99D3
Sequence coordinates
Member of large scale dataset(s)	T(Y;3)L&S_set1 Set of Y;3 translocation stocks designed to allow generation of aneuploid animal by crossing two members of the set with breakpoints flanking the region of interest. For most regions, animals carrying both the duplication and the deficiency of the region between the autosomal breakpoints can be recovered and unambiguously identified. (Lindsley et al., 1972)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	Dp(1;Y)B^SYy⁺ (Seattle-La Jolla Drosophila Laboratories, 1971, Lindsley et al., 1972)
Mutagen	X ray (Seattle-La Jolla Drosophila Laboratories, 1971, Lindsley et al., 1972)
Class of aberration (relative to progenitor)	chromosomal_translocation (Seattle-La Jolla Drosophila Laboratories, 1971, Kongsuwan et al., 1986, Kongsuwan et al., 1985, Warmke et al., 1989, Lindsley et al., 1972)
Breakpoints	[];99C8 (Buescher and Chia, 1997) h1-h17;99C-99D (Seattle-La Jolla Drosophila Laboratories, 1971, Lindsley et al., 1972) h1-h17;99D1-99D2 (Kongsuwan et al., 1986) h1-h25;99C8 (Kongsuwan et al., 1985) h1-h25;99D3 (Warmke et al., 1989)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << M(3)99B << bk2 << l(3)99Dg
Genetic mapping information
Comments
Comments on Cytology
	Breakpoint on the Y chromosome not reported. (Warmke et al., 1989) From cytological and genetic criteria the likely order of euchromatin deficiency breakpoints from proximal to distal is Dp(3;1)74 - Dp(3;1)78 - T(Y;3)B81 - Dp(3;1)R14 - Dp(3;1)R10/Dp(3;1)67N - Dp(3;1)67A - Dp(3;1)3. (Kongsuwan et al., 1986) Limits of break 1 from polytene analysis (FBrf0022239) Limits of break 2 from polytene analysis (FBrf0049882)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	ttk (BDGP Project Members, 1994-1999)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	T(Y;3)B81/Df(1)bb158 male sterile
NOT in combination with other aberrations	Heterozygotes with T(Y;3)B226 are inviable. (Kongsuwan et al., 1986) X/T(Y;3)B81 males are fertile. (Seattle-La Jolla Drosophila Laboratories, 1971, Lindsley et al., 1972) X/T(Y;3) male fertile
Stocks ( 0 )

Notes on Origin
Discoverer	B.S. Baker.
	Associated with: In(3)B81. (Lindsley et al., 1972) Induced in mature sperm. (Seattle-La Jolla Drosophila Laboratories, 1971)
Balancer / Genotype Variants of the Aberration

Separable Components
	Df(3R)B81
Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	B81 (Seattle-La Jolla Drosophila Laboratories, 1971) Df(3R)B81 (Smulders-Srinivasan and Lin, 2003, Li and Li, 2003) T(Y;3)B81 unnamed (Buescher and Chia, 1997)
Name Synonym
Secondary FlyBase IDs

References ( 17 )
Research paper	Brumby et al., 2004, Genetics 168(1): 227--251 A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila. [FBrf0180291] Li and Li, 2003, Genetics 164(1): 247--258 Drosophila gain-of-function mutant RTK Torso triggers ectopic Dpp and STAT signaling. [FBrf0158996] Smulders-Srinivasan and Lin, 2003, Genetics 165(4): 1971--1991 Screens for piwi suppressors in Drosophila identify dosage-dependent regulators of germline stem cell division. [FBrf0167655] Buescher and Chia, 1997, Development 124(3): 673--681 Mutations in lottchen cause cell fate transformations in both neuroblast and glioblast lineages in the Drosophila embryonic central nervous system. [FBrf0092481] Nambu et al., 1996, Gene 172(2): 249--254 The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human hypoxia-inducible factor 1 and Drosophila single-minded. [FBrf0088642] Bilder and Scott, 1995, Genetics 141(3): 1087--1100 Genomic regions required for morphogenesis of the Drosophila embryonic midgut. [FBrf0083777] Harbecke and Lengyel, 1995, Rouxs Arch. Dev. Biol. 204(5): 308--329 Genes controlling posterior gut development in the Drosophila embryo. [FBrf0082073] Warmke et al., 1989, Genetics 122: 139--151 Co-localization to chromosome bands 99E1-3 of the Drosophila melanogaster myosin light chain-2 gene and a haplo-insufficient locus that affects flight behavior. [FBrf0049882] Jurgens and Weigel, 1988, Rouxs Arch. Dev. Biol. 197(6): 345--354 Terminal versus segmental development in the Drosophila embryo: the role of the homeotic gene fork head. [FBrf0064887] Kongsuwan et al., 1986, Genetics 112: 539--550 Deficiency analysis of the tip of chromosome 3R in Drosophila melanogaster. [FBrf0044462] Kongsuwan et al., 1985, Nature 317(6037): 555--558 A Drosophila Minute gene encodes a ribosomal protein. [FBrf0043337] Lindsley et al., 1972, Genetics 71: 157--184 Segmental aneuploidy and the genetic gross structure of the Drosophila genome. [FBrf0023910] Seattle-La Jolla Drosophila Laboratories, 1971, D. I. S. 47(Suppl.): 7pp The use of Y-autosome translocations in the construction of autosomal duplications and deficiencies. (Special supplement to DIS 47). [FBrf0022239]
Personal communication to FlyBase	BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]