Aberration Dmel\Tp(2;3)dp

General Information
Symbol	Dmel\Tp(2;3)dp	Species	D. melanogaster
Name	Transposition (2;3) dumpy	FlyBase ID	FBab0009838
Feature type	interchromosomal_transposition
Also Known As	T(2;3)dp

Computed Breakpoints include	27E1-27E2;32E2;34D4;34D8-34E1;41;45A;48A1;80-81
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order	2Lt - 27E1 \| 32E3 - 34D4 \| 41 - 34E1 \| 48A1 - 2Rt ; 3Lt - 80 \| (41 - 45A \| 27E2 - 32E2 \| 45A - 48A1) \| 81 - 3Rt 2Lt - 27E1 \| 32E3 - 34D4 \| 41 - 34E1 \| 48A1 - 2Rt ; 3Lt - 80 \| (41 - 45A \| 27E2 - 32E2 \| 45A - 48A1) \| 81 - 3Rt Ashburner et al., 1981)
Progenitor	ptc^tuf-1 (Phillips et al., 1990)
Mutagen	spontaneous (Woodruff and Ashburner, 1979)
Class of aberration (relative to progenitor)
Breakpoints	27E1--2;32E2;[];34D7--34E1;41;45A;48A1;80--81 (Woodruff and Ashburner, 1979)
Causes alleles	b^36f (Ashburner et al., 1999.10.12)
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)34Db << bk3 << Sos << RpII33 << bk4
Genetic mapping information
Comments
Comments on Cytology
	8 breaks. Break 4 is in the region covered by Df(2R)M41A-vg11. (Curry, 1939) Limits of break 1 from polytene analysis (FBrf0033164) Limits of break 2 from polytene analysis (FBrf0033164) Left limit of break 3 from complementation mapping against l(2)34Db (citation unavailable) Right limit of break 3 from complementation mapping against Sos (citation unavailable) Left limit of break 4 from complementation mapping against RpII33 (citation unavailable) Right limit of break 4 from polytene analysis (FBrf0033164) Limits of break 5 from polytene analysis (FBrf0033164) Limits of break 6 from polytene analysis (FBrf0033164) Limits of break 7 from polytene analysis (FBrf0033164) Limits of break 8 from polytene analysis (FBrf0033164)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	b (Ashburner et al., 1981) DNApol-γ35 (Roote, 1997.6.3) RpII33 (Roote, 1997.6.3)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Ance (Roote, 1997.6.3) NimA (Ashburner et al., 1981) rk (Ashburner et al., 1981)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Tp(2;3)dp/Df(2R)M41A-vg11 flies live but have a strong effect (possibly due to position effect) resembling rl. (Curry, 1939) Tp(2;3)dp/CyO semilethal
NOT in combination with other aberrations	Flies have a rough eye phenotype. (Curry, 1939) homozygous lethal
Stocks ( 1 )
Bloomington	237 Bl¹/Tp(2;3)dp, b^36f
Notes on Origin
Discoverer	Nichols-Skoog, 16th May 1936.

Balancer / Genotype Variants of the Aberration

Separable Components
	Dp(2;3)dp
Other Comments
	"spontaneous" was stated as tentative. Not necessarily associated with dp^36e May be associated with a dominant rough eye mutation. Chromosome 3 breaks inferred from genetic data (Muller, 1942; Cooper, Zimmering and Krivshenko, 1955, Proc. Nat. Acad. Sci. USA 41: 911-14).
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	Df(2L)b36f In(2LR)dp (Curry, 1939, ) T(2;3)dp (Ashburner et al., 1981, Phillips et al., 1990, Ashburner et al., 1982, Woodruff and Ashburner, 1979, ) Tp(2;3)dp
Name Synonym	Transposition (2;3) dumpy
Secondary FlyBase IDs

References ( 11 )
Research paper	Phillips et al., 1990, Development 110: 105--114 The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs. [FBrf0051546] Ashburner et al., 1982, Genetics 102: 421--435 The genetics of a small autosomal region of Drosophila melanogaster, including the structural gene for alcohol dehydrogenase. [FBrf0038050] Ashburner et al., 1981, D. I. S. 56: 186--191 Report of New Mutants. [FBrf0036112] Woodruff and Ashburner, 1979, Genetics 92: 133--149 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0033164] Cooper et al., 1955, Proc. Natl. Acad. Sci. U.S.A. 41: 911--914 Interchromosomal effects and segregation. [FBrf0010363] Muller, 1942, D. I. S. 16: 64 Insertional translocation involved in 'In(dp)'. [FBrf0005657] Curry, 1939, D. I. S. 12: 45--47 [New mutants report.] [FBrf0063388] Morgan et al., 1937, Yb. Carnegie Instn, Wash. 36: 298--305 Constitution of the germinal material in relation to heredity. [FBrf0064034]
Personal communication to FlyBase	Ashburner et al., 1999.10.12, Adh. Adh. [FBrf0112153] Roote, 1997.6.3, Formalized genetic data for deletions. Formalized genetic data for deletions. [FBrf0093853]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]