Aberration Dmel\Df(2R)nap1

General Information
Symbol	Dmel\Df(2R)nap1	Species	D. melanogaster
Name		FlyBase ID	FBab0010165
Feature type	chromosomal_deletion

Computed Breakpoints include	41D2-41E1;42B1-42B3
Deleted segment	41D2--42B3
Sequence coordinates
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Gellon et al., 1997, Kreber, 1994.3.17)
Breakpoints	41D2-41E1;42B1-42B3 (Kreber, 1994.3.17, Gellon et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << EcR << l(2)42Bd << bk2
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0075275)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	ap (Pueyo et al., 2000, Coelho et al., 2005, Gambetta and Mueller, 2009.8.18) BubR1 (Myster et al., 2004, Basu et al., 1999, Spradling et al., 1999, BDGP Project Members, 1994-1999) EcR (Spradling et al., 1999, BDGP Project Members, 1994-1999, Bender, 1996, Gellon et al., 1997) esg (BDGP Project Members, 1994-1999) kune (Gambetta and Mueller, 2009.8.18) l(2)42Bb (Bender, 1996) l(2)42Bc (Bender, 1996) l(2)42Bd (Bender, 1996) l(2)09851 (Spradling et al., 1999, BDGP Project Members, 1994-1999, Gambetta and Mueller, 2009.8.18) l(2)c00221 (Thibault et al., 2004) l(2)k09848 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k14710 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)NC12 (Myster et al., 2004) l(2)NC14 (Myster et al., 2004) l(2)NC45 (Myster et al., 2004) l(2)NC47 (Myster et al., 2004) l(2)NC85 (Myster et al., 2004) l(2)NC114 (Myster et al., 2004) l(2)NC136 (Myster et al., 2004, Gambetta and Mueller, 2009.8.18) l(2)NC139 (Myster et al., 2004) l(2)NC148 (Myster et al., 2004) l(2)NC192 (Myster et al., 2004) laccase2 (Gambetta and Mueller, 2009.8.18) Nipped-A (Myster et al., 2004, Gambetta and Mueller, 2009.8.18) S(CycE^JP)2.4 (Brumby et al., 2004) Src42A (Spradling et al., 1999, BDGP Project Members, 1994-1999) sxc (Myster et al., 2004, Gambetta and Mueller, 2009.8.18, Gambetta et al., 2009) vlc (Spradling et al., 1999, Myster et al., 2004, BDGP Project Members, 1994-1999, Gambetta and Mueller, 2009.8.18)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Bap170 (Rendina et al., 2010) CG17486 (Myster et al., 2004) CG17683 (Myster et al., 2004) CG40127 (Myster et al., 2004) Eb1 (Brumby et al., 2004) IntS3 (Myster et al., 2004) jing (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)309 (Myster et al., 2004) l(2)05315 (BDGP Project Members, 1994-1999) l(2)k14805 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)NC30 (Myster et al., 2004) l(2)NC83 (Myster et al., 2004) l(2)NC133 (Myster et al., 2004) l(2)NC204 (Myster et al., 2004) Nipped-B (Myster et al., 2004, Gambetta and Mueller, 2009.8.18) p120ctn (Myster et al., 2004) rl (Myster et al., 2004) RpL38 (Myster et al., 2004, Gambetta and Mueller, 2009.8.18) Stlk (Myster et al., 2004) Tdc1 (Cole et al., 2005) Tdc2 (Cole et al., 2005) uex (Myster et al., 2004)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Lethal in combination with Ab(2;?)2.5-58S12. (Brumby et al., 2004)
NOT in combination with other aberrations	The Df(2R)nap1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Heterozygosity for Df(2R)nap1 results in 4.0% X chromosome nondisjunction and 1.6% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003) Intermediate second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1: malformed phenotype penetrance 25-75%. (Halsell and Kiehart, 1998)
Stocks ( 3 )
Bloomington	1006 Df(2R)nap1/Dp(2;2)BG, In(2LR)Gla, wg^Gla-1
Kyoto	106164 Df(2R)nap1/In(2LR)Gla, Dp(2;2)BG, wg^Gla-1 101444 Df(2R)nap1 / In(2LR)Gla, Dp(2;2)BG, wg^Gla-1
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2)nap1 (Pueyo and Couso, 2004) Df(2R)nap1 (Huang et al., 2004, Collett, 2008.2.16, Rendina et al., 2010, Gambetta et al., 2009, Gambetta and Mueller, 2009.8.18) Df(2R)nap¹ (Yedvobnick et al., 2001, Pueyo et al., 2000, Lu and Li, 1999, Kreber, 1994.3.17)
Name Synonym
Secondary FlyBase IDs

References ( 29 )

Generate a list of	All references relating to this aberration ( 29 )

List References by type	Research paper ( 22 ) Supplementary material ( 2 ) Personal communication to FlyBase ( 3 ) FlyBase analysis ( 1 ) Computer file ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...