FB2022_02, released March 29, 2022

Aberration: Dmel\Df(2R)nap1

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General Information
Symbol
Df(2R)nap1
Species
D. melanogaster
Name
FlyBase ID
FBab0010165
Feature type
chromosomal_deletion
Also Known As
Df(2R)nap1
Computed Breakpoints include

41D2-41E1;42B1-42B3

Features within 41D2--42B3
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Gellon et al., 1997, Kreber, 1994.3.17)
Breakpoints

41D2-41E1;42B1-42B3

(Gellon et al., 1997, Kreber, 1994.3.17)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << EcR << l(2)42Bd << bk2

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0075275)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ap
(Gambetta and Müller, 2009.8.18, Coelho et al., 2005, Pueyo et al., 2000)
BubR1
(Myster et al., 2004, Basu et al., 1999, Spradling et al., 1999, BDGP Project Members, 1994-1999)
EcR
(Spradling et al., 1999, Gellon et al., 1997, Bender, 1996, BDGP Project Members, 1994-1999)
esg
(BDGP Project Members, 1994-1999)
gus
(Kugler et al., 2010)
kune
(Gambetta and Müller, 2009.8.18)
l(2)42Bb
(Bender, 1996)
l(2)42Bc
(Bender, 1996)
l(2)42Bd
(Bender, 1996)
l(2)09851
(Gambetta and Müller, 2009.8.18, Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)c00221
(Thibault et al., 2004)
l(2)k09848
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)NC12
(Myster et al., 2004)
l(2)NC14
(Myster et al., 2004)
l(2)NC45
(Myster et al., 2004)
l(2)NC47
(Myster et al., 2004)
l(2)NC85
(Myster et al., 2004)
l(2)NC114
(Myster et al., 2004)
l(2)NC139
(Myster et al., 2004)
l(2)NC148
(Myster et al., 2004)
l(2)NC192
(Myster et al., 2004)
Nipped-A
(Gambetta and Müller, 2009.8.18, Myster et al., 2004)
Not3
(Gambetta and Müller, 2009.8.18, Myster et al., 2004)
S(CycEJP)2.4
(Brumby et al., 2004)
Src42A
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
stw
(Gambetta and Müller, 2009.8.18)
sxc
(Gambetta and Müller, 2009.8.18, Gambetta et al., 2009, Myster et al., 2004)
Ttc7
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
vlc
(Gambetta and Müller, 2009.8.18, Myster et al., 2004, Spradling et al., 1999, BDGP Project Members, 1994-1999)
Partially deleted / disrupted
Molecular Data
Completely deleted
ap
(Bieli et al., 2015)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Lethal in combination with Ab(2;?)2.5-58S12.

    (Brumby et al., 2004)
    NOT in combination with other aberrations

    The Df(2R)nap1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Heterozygosity for Df(2R)nap1 results in 4.0% X chromosome nondisjunction and 1.6% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 25-75%.

    (Halsell and Kiehart, 1998)
    Stocks (3)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    References (35)