Aberration Dmel\Df(2R)nap14

General Information
Symbol	Dmel\Df(2R)nap14	Species	D. melanogaster
Name		FlyBase ID	FBab0010168
Feature type	chromosomal_deletion

Computed Breakpoints include	41B-41C;42A16-42B1
Deleted segment	41B--42B1
Sequence coordinates
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Kreber, 1994.3.17)
Breakpoints	41B-41C;42A16-42B1 (Kreber, 1994.3.17)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0075275)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	gus (Styhler et al., 2002) l(2)42Aa (Roote and Ashburner, 2005.6) l(2)42Ab (Roote and Ashburner, 2005.6) l(2)42Ac (Roote and Ashburner, 2005.6)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	RpL38 (Marygold et al., 2005) Tdc1 (Cole et al., 2005) Tdc2 (Cole et al., 2005)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 2 )
Bloomington	4308 Df(2R)nap14/CyO
Kyoto	107681 Df(2R)nap14/CyO
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2R)nap14 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but the eye colour phenotype in the presence of Df(2R)nap14 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. (Mason et al., 2004)
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	Df(2R)8-13-4 Df(2R)nap14 Df(2R)nap¹⁴ (Kreber, 1994.3.17) nap8-13-4 (Kreber, 1994.3.17) nap8-13-14 (Kreber, 1994.3.17)
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Cole et al., 2005, J. Biol. Chem. 280(15): 14948--14955 Two functional but noncomplementing Drosophila tyrosine decarboxylase genes. [FBrf0187786] Marygold et al., 2005, Genetics 169(2): 683--695 Genetic analysis of RpL38 and RpL5, two Minute genes located in the centric heterochromatin of chromosome 2 of Drosophila melanogaster. [FBrf0187649] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Presgraves, 2003, Genetics 163(3): 955--972 A fine-scale genetic analysis of hybrid incompatibilities in Drosophila. [FBrf0158988] Styhler et al., 2002, Dev. Cell 3(6): 865--876 VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS. [FBrf0155679]
Personal communication to FlyBase	Roote and Ashburner, 2005.6, l(2)43A mutations. l(2)43A mutations. [FBrf0188639] Kreber, 1994.3.17, Df(2R)nap chromosomes. Df(2R)nap chromosomes. [FBrf0075275]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]