Aberration Dmel\Df(1)L-1-2

General Information
Symbol	Dmel\Df(1)L-1-2	Species	D. melanogaster
Name		FlyBase ID	FBab0010213
Feature type	chromosomal_deletion
Also Known As	L-I-2

Computed Breakpoints include	6F1-6F2;7A3-7A4
Deleted segment	6F1--7A4
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	hobo dysgenesis (Simpson and Wieschaus, 1990)
Class of aberration (relative to progenitor)	chromosomal_deletion (Wieschaus, 1992)
Breakpoints	6F1-6F2;7A3-7A4 (Wieschaus, 1992)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	cm << bk1 << nullo << l(1)7Aa << bk2 << l(1)7Ab
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0075226)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	l(1)6Fd (Simpson and Wieschaus, 1990) l(1)7Aa (Simpson and Wieschaus, 1990) nullo (Simpson and Wieschaus, 1990, Rose and Wieschaus, 1992) Sxl (Sheen et al., 1993, Simpson and Wieschaus, 1990, Rose and Wieschaus, 1992)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	cm (Simpson and Wieschaus, 1990, Rose and Wieschaus, 1992) l(1)6Eb (Simpson and Wieschaus, 1990) l(1)6Ed (Simpson and Wieschaus, 1990, Sheen et al., 1993) l(1)6Ef (Simpson and Wieschaus, 1990, Rose and Wieschaus, 1992) l(1)7Aa (Rose and Wieschaus, 1992) l(1)7Ab (Sheen et al., 1993) l(1)7Ad (Sheen et al., 1993) l(1)air7 (Sheen et al., 1993) stout (Simpson and Wieschaus, 1990)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 0 )

Notes on Origin
Discoverer
	on Uc chromosome which contains a readily mobilized gypsy element at ct
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	A hobo, with open reading frame towards the telomere, is inserted at the deletion breakpoint. (Sheen et al., 1993) Derived from an unstable chromosome, Uc, or a chromosome placed in trans to Uc, which was put through hobo dysgenesis. (Simpson and Wieschaus, 1990)
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(1)L-1-2 L-I-2 (Simpson and Wieschaus, 1990, Rose and Wieschaus, 1992, ) U-1 (Sheen et al., 1993)
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Sheen et al., 1993, Genetics 133(2): 315--334 Genetic instability in Drosophila melanogaster mediated by hobo transposable elements. [FBrf0058562] Rose and Wieschaus, 1992, Genes Dev. 6: 1255--1268 The Drosophila cellularization gene nullo produces a blastoderm-specific transcript whose levels respond to the nucleocytoplasmic ratio. [FBrf0056104] Simpson and Wieschaus, 1990, Development 110: 851--863 Zygotic activity of the nullo locus is required to stabilize the actin-myosin network during cellularization in Drosophila. [FBrf0051589]
Personal communication to FlyBase	Wieschaus, 1992, [title not yet available] [title not yet available] [FBrf0075226]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]