FlyBase Aberration Report: Dmel\Df(3L)Ar14-8

General Information

Symbol

Df(3L)Ar14-8

Species

D. melanogaster

Name

FlyBase ID

FBab0010230

Feature type

chromosomal_deletion

Also Known As

Df(3L)emc5, AR14-8

Computed Breakpoints include

61C4;62A8

Features within 61C4--62A8

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Wilson et al., 1997, Isaac and Andrew, 1996, Pauli et al., 1995, Roseman et al., 1995, Castrillon et al., 1993)

Breakpoints

61C3-61C4;62A8

(Wilson et al., 1997, Isaac and Andrew, 1996, Roseman et al., 1995, Castrillon et al., 1993)

61C3-61C4;62A

(Pauli et al., 1995)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

klar << bk1 << l(3)61Da << cue << bk2

Genetic mapping information

Comments

Comments on Cytology

proximal to 61C4-7

(Vize, 1995.6.6)

Left limit of break 1 from non-inclusion of klar (FBrf0079818) Right limit of break 1 from polytene analysis (FBrf0064394) Limits of break 2 from polytene analysis (FBrf0064394)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Aplip1

(Horiuchi et al., 2005)

Cep290

(Basiri et al., 2014)

cue

(Castrillon et al., 1993)

emc

(Spradling et al., 1999, Szeged Stock Center, 1998-)

Glut1

(Szeged Stock Center, 1998-)

hfp

(Quinn et al., 2004, Van Buskirk and Schupbach, 2002)

Hmbs

(Spradling et al., 1999)

Klp61F

(Spradling et al., 1999, Wilson et al., 1997)

l(3)61Da

(Roseman et al., 1995)

l(3)00835

(Spradling et al., 1999)

l(3)05967

(Spradling et al., 1999)

l(3)L1170b

(Spradling et al., 1999)

l(3)L2049

(Spradling et al., 1999)

l(3)L3130

(Spradling et al., 1999)

l(3)neo5

(Spradling et al., 1999)

l(3)S003606

(Szeged Stock Center, 1998-)

l(3)S090609

(Szeged Stock Center, 1998-)

ND-ACP

(Spradling et al., 1999)

Pcyt1

(Schupbach, 2000.3.4)

Rac1

(Prokopenko et al., 1999, Sawamoto et al., 1999, Boutros et al., 1998)

rho

(Tjota et al., 2011, Wasserman et al., 2000)

(Gallio et al., 2004, Wasserman et al., 2000)

trio

(Brumby et al., 2004, Szeged Stock Center, 1998-)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

The salivary gland distal tip does not initiate turning and migration in embryos homozygous for Df(3L)Ar14-8 by stage 14.

(Jattani et al., 2009)

Df(3L)Ar14-8 embryos show defects in tracheal invagination.

(Myat et al., 2005)

Has no effect on the ommatidial polarity phenotype of msn^EP549 when driven by Scer\GAL4^hs.2sev.

(Paricio et al., 1999)

Dominant suppressor of dsh^hs.sev.B mutant polarity phenotype.

(Boutros et al., 1998)

Dominantly suppresses the Kr^If-1/+ eye phenotype.

(Carrera et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Stocks (3)

Bloomington

439

Df(3L)Ar14-8, red¹/TM2, p^p

Kyoto

108902

Df(3L)Ar14-8, red¹/TM2, p^p

103298

Df(3L)Ar14-8, red¹ / TM2, emc² p^p Ubx¹³⁰ e^s

Notes on Origin

Discoverer

H. Ellis.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

The Df(3L)Ar14-8 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but the eye colour phenotype in the presence of Df(3L)Ar14-8 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.

(Mason et al., 2004)

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

AR14-8

(Hirose et al., 2001)

Ar14-8

(Basiri et al., 2014)

Df(3L)AR14-8

(Isaac and Andrew, 1996)

Df(3L)Ac14-8

(Castrillon et al., 1993)

Df(3L)Ar14-8

(Thimgan et al., 2015, Cuykendall et al., 2014, Tjota et al., 2011, Jattani et al., 2009, Crest et al., 2007, Slack et al., 2006)

Df(3L)Ar14.8

(Gildea et al., 2000)

Df(3L)Emc5

(Jenny et al., 2003)

Df(3L)H5

(Isaac and Andrew, 1996)

Df(3L)emc5

(Brumby et al., 2004, Weber et al., 2003, Lee et al., 2001, Fanto et al., 2000, Firth et al., 2000, Paricio et al., 1999, Sawamoto et al., 1999, Boutros et al., 1998, Takano, 1998, Bilder and Scott, 1995, Roseman et al., 1995, Vize, 1995.6.6, Weber et al., 1995)

Df(3L)emc5(Rac1)

(Montrasio et al., 2007)

Df(3l)emc5

(Mirkovic et al., 2011)

Dfemc5

(Weber et al., 2003)

emc5

(Hirose et al., 2001)

Name Synonyms

Secondary FlyBase IDs

FBab0024871

References (58)

Report Sections

Open Close