A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(3L)Ar14-8

General Information
SymbolDmel\Df(3L)Ar14-8SpeciesD. melanogaster
NameFlyBase IDFBab0010230
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data klar << bk1 << l(3)61Da << cue << bk2
Sequence coordinates
Deleted segment61C4--62A8
Duplicated segment
Computed Breakpoints include 61C4;62A8
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)
chromosomal_deletion
(Isaac and Andrew, 1996, Castrillon et al., 1993, Pauli et al., 1995, Roseman et al., 1995, Wilson et al., 1997)
Breakpoints
61C3-61C4;62A8
(Castrillon et al., 1993, Roseman et al., 1995, Isaac and Andrew, 1996, Wilson et al., 1997)
61C3-61C4;62A
(Pauli et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
Left limit of break 1 from non-inclusion of klar (FBrf0079818) Right limit of break 1 from polytene analysis (FBrf0064394) Limits of break 2 from polytene analysis (FBrf0064394)
 
proximal to 61C4-7
(Vize, 1995.6.6)
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Aplip1
(Horiuchi et al., 2005)
trio
(Szeged Stock Center, 1998-, Brumby et al., 2004)
mtacp1
(Spradling et al., 1999)
l(3)02640
(Spradling et al., 1999)
ru
(Wasserman et al., 2000, Gallio et al., 2004)
rho
(Wasserman et al., 2000)
cue
(Castrillon et al., 1993)
pUf68
(Van Buskirk and Schupbach, 2002, Quinn et al., 2004)
Rac1
(Boutros et al., 1998, Sawamoto et al., 1999, Prokopenko et al., 1999)
Klp61F
(Wilson et al., 1997, Spradling et al., 1999)
Cct1
(Schupbach, 2000.3.4)
emc
(Szeged Stock Center, 1998-, Spradling et al., 1999)
l(3)neo5
(Spradling et al., 1999)
l(3)00835
(Spradling et al., 1999)
l(3)05967
(Spradling et al., 1999)
l(3)L2049
(Spradling et al., 1999)
l(3)L3130
(Spradling et al., 1999)
l(3)61Da
(Roseman et al., 1995)
l(3)S090609
(Szeged Stock Center, 1998-)
l(3)S007412
(Szeged Stock Center, 1998-)
l(3)S003606
(Szeged Stock Center, 1998-)
l(3)L1170b
(Spradling et al., 1999)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
fwd
(Brill et al., 2000)
klar
(Vize, 1995.6.6)
trh
(Isaac and Andrew, 1996, Spradling et al., 1999)
dlt
(Spradling et al., 1999)
l(3)L5150
(Spradling et al., 1999)
l(3)06240
(Spradling et al., 1999)
l(3)S104103
(Szeged Stock Center, 1998-)
l(3)S041919
(Szeged Stock Center, 1998-)
gim
(Myat et al., 2005)
fang
(Myat et al., 2005)
gloin
(Myat et al., 2005)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Df(3L)Ar14-8 embryos show defects in tracheal invagination.
(Myat et al., 2005)
Deficient embryos show an uninterpretable mutant midgut phenotype.
(Bilder and Scott, 1995)
Dominant suppressor of dshhs.sev.B mutant polarity phenotype.
(Boutros et al., 1998)
Dominantly suppresses the KrIf-1/+ eye phenotype.
(Carrera et al., 1998)
Has no effect on the ommatidial polarity phenotype of msnEP549 when driven by Scer\GAL4hs.2sev.
(Paricio et al., 1999)
Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.
(Pauli et al., 1995)
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
(Halsell and Kiehart, 1998)
hide Position Effect Variegation Data
  
hide Stocks ( 3 )
Bloomington
439
Df(3L)Ar14-8, red1/TM2, pp
Kyoto
108902
Df(3L)Ar14-8, red1/TM2, pp
103298
Df(3L)Ar14-8, red1 / TM2, emc2 pp Ubx130 es
hide Notes on Origin
Discoverer
H. Ellis.
 
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      The Df(3L)Ar14-8 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(3L)Ar14-8 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.
      (Mason et al., 2004)
      hide Synonyms & Secondary IDs ( 8 )
      Reported As
      Symbol Synonym
      Df(3L)Ac14-8
      (Castrillon et al., 1993, )
      Df(3L)AR14-8
      (Isaac and Andrew, 1996)
      Df(3L)Ar14-8
      (Crest et al., 2007)
      Df(3L)Ar14.8
      (Gildea et al., 2000)
      Df(3L)emc5
      (Weber et al., 2003, Brumby et al., 2004, Lee et al., 2001, Firth et al., 2000, Fanto et al., 2000, Paricio et al., 1999, Sawamoto et al., 1999, Boutros et al., 1998, Takano, 1998, Weber et al., 1995, Roseman et al., 1995, Bilder and Scott, 1995, Vize, 1995.6.6, )
      Df(3L)Emc5
      (Jenny et al., 2003)
      Df(3L)H5
      (Isaac and Andrew, 1996)
      Dfemc5
      (Weber et al., 2003)
      Name Synonym
      Secondary FlyBase IDs
      • FBab0024871
      hide References ( 48 )
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      hide Recent research papers ( 1 )
      Crest et al., 2007, Genetics 175(2): 567--584
      Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644]
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