Aberration Dmel\Df(2L)JS17

General Information
Symbol	Dmel\Df(2L)JS17	Species	D. melanogaster
Name		FlyBase ID	FBab0022191
Feature type	chromosomal_deletion
Also Known As	Df(2)JS17

Computed Breakpoints include	23C1-23C2;23E1-23E2
Deleted segment	23C1--23E2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Sekelsky et al., 1995, Kooistra et al., 1997, Ghabrial et al., 1998)
Breakpoints	23C1-23C2;23E1-23E2 (Sekelsky et al., 1995, Ghabrial et al., 1998) 23C;23E (Kooistra et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << lilli << Mad << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0080380) Right limit of break 1 from inclusion of lilli (FBrf0067338) Limits of break 2 from polytene analysis (FBrf0080380)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Chd1 (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23CDa (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23CDb (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23CDc (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23CDd (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23CDe (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23CDf (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23CDg (Ferro, 2002.12) l(2)23Da (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23Db (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23Dc (Eeken, 2000.2.29, Ferro, 2002.12) l(2)23Dd (Eeken, 2000.2.29, Ferro, 2002.12) l(2)a4 (Su et al., 2001) l(2)k9 (Su et al., 2001) l(2)k05816 (BDGP Project Members, 1994-1999) lilli (Spradling et al., 1999, Eeken, 2000.2.29, Su et al., 2001, Wittwer et al., 2001, Ferro, 2002.12, BDGP Project Members, 1994-1999) Mad (Yu et al., 1998, Spradling et al., 1999, Su et al., 2001, BDGP Project Members, 1994-1999, Raftery et al., 1995, Sekelsky et al., 1995, Newfeld et al., 1996, Newfeld et al., 1997) okr (Ghabrial et al., 1998, Eeken et al., 1997, Kooistra et al., 1997) Rrp1 (Huang et al., 1998, Huang et al., 1996) toc (Spradling et al., 1999, Eeken, 2000.2.29, Su et al., 2001, Ferro, 2002.12, BDGP Project Members, 1994-1999) γTub23C (Eeken, 2000.2.29, Ferro, 2002.12, Vázquez et al., 2008)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Cy (Stefancsik, 2002.5.22) l(2)k14816 (BDGP Project Members, 1994-1999) Pdsw (Spradling et al., 1999, BDGP Project Members, 1994-1999) Rbp9 (BDGP Project Members, 1994-1999) RpS21 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Sec61α (BDGP Project Members, 1994-1999) Syt1 (Stefancsik, 2002.5.22) Thor (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Inferred to overlap with: Df(2L)3G. (Vázquez et al., 2008) Lethal in combination with Df(2L)3G. (Vázquez et al., 2008) Inferred to overlap with: Df(2L)JS25. (Ferro, 2002.12) Fails to complement T(2;3)DTD46.4. (Su et al., 2001)
NOT in combination with other aberrations	The Df(2L)JS17 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Maternal enhancement of the dpp^hr4 lethality. The lethal interaction is due to a loss of dorsal-most fates in the embryos, demonstrated by loss of amnioserosa cells. (Raftery et al., 1995) Maternal effect enhancement of dpp mutant phenotype. (Sekelsky et al., 1995)
Stocks ( 2 )
Bloomington	1567 Df(2L)JS17, dpp^d-ho/CyO, P{en1}wg^en11
Kyoto	106390 Df(2L)JS17, dpp^d-ho/CyO, P{en1}wg^en11
Notes on Origin
Discoverer	Gelbart.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2)JS17 (Stefancsik, 2002.5.22, Kooistra et al., 1997, Eeken et al., 1997) Df(2L)JS17 (Konev et al., 2007, Wei and Rong, 2007, Vázquez et al., 2008, Weiss et al., 2012, Twombly et al., 2009, Melicharek et al., 2008, Popkova et al., 2012) JS17 (Gorski et al., 2003)
Name Synonym
Secondary FlyBase IDs

References ( 33 )

Generate a list of	All references relating to this aberration ( 33 )

List References by type	Research paper ( 25 ) Personal communication to FlyBase ( 4 ) Abstract ( 3 ) FlyBase analysis ( 1 )
Recent research papers ( 2 )
	Popkova et al., 2012, PLoS Genet. 8(12): e1003159 Polycomb controls gliogenesis by regulating the transient expression of the gcm/glide fate determinant. [FBrf0220515] Weiss et al., 2012, Genetics 190(2): 581--600 Huntingtin Aggregation Kinetics and Their Pathological Role in a Drosophila Huntington's Disease Model. [FBrf0217529] Show all research papers ...