Aberration Dmel\Df(2L)Trf-C6R31

General Information
Symbol	Dmel\Df(2L)Trf-C6R31	Species	D. melanogaster
Name	Df(2L)TBP-related factor-C6R31	FlyBase ID	FBab0022203
Feature type	chromosomal_deletion
Also Known As	Df(2L) Trf-C6R31

Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	P{lacW}Trf¹ (Crowley et al., 1993) P{lacW}Trf² (Crowley et al., 1993)
Mutagen	Delta2-3 (Crowley et al., 1993)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Bsg (BDGP Project Members, 1994-1999) l(2)k06327 (BDGP Project Members, 1994-1999) Mcr (Crowley et al., 1993) MED20 (Crowley et al., 1993) Trf (Crowley et al., 1993)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Fic (BDGP Project Members, 1994-1999) l(2)gl (Mason et al., 2004) l(2)k10210 (BDGP Project Members, 1994-1999) l(2)k16919 (BDGP Project Members, 1994-1999) mts (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for Df(2L)Trf-C6R31 results in 1.7% X chromosome nondisjunction and 1.9% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Homozygotes show embryonic lethality. (Crowley et al., 1993)
Stocks ( 3 )
Bloomington	140 y¹ w^67c23; Df(2L)Trf-C6R31/CyO
Kyoto	108892 y¹ w^67c23; Df(2L)Trf-C6R31/CyO 103326 y¹ w^67c23 ; Df(2L)Trf-C6R31 / SM1
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2L)Trf-C6R31 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is assumed to be a false positive result (the suppressor may not be within the bounds of the deficient region) because the 2L TAS array on the chromosome is reduced (as assayed by in situ hybridization) and it has previously been shown (FBrf0137248, FBrf0158986) that partial or complete deficiency of the 2L TAS array on the homologue suppresses silencing of brown-red variants of P{3'WP-2,w^var}2Lt. (Mason et al., 2004) "FBti0003098 == P{lacW}Trf¹" was stated as tentative. "FBti0003099 == P{lacW}Trf²" was stated as tentative. (Crowley et al., 1993)
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(2L)Trf-C6R31 (Tanaka and Nakamura, 2008) Df(2L) Trf-C6R31 (Jordan et al., 2006) Df(2L) TRF-C6R31 (Fiehler and Wolff, 2008)
Name Synonym	Df(2L)TBP-related factor-C6R31
Secondary FlyBase IDs

References ( 11 )
Research paper	Fiehler and Wolff, 2008, Dev. Biol. 313(2): 533--544 Nemo is required in a subset of photoreceptors to regulate the speed of ommatidial rotation. [FBrf0203152] Tanaka and Nakamura, 2008, Development 135(6): 1107--1117 The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly. [FBrf0204304] Jordan et al., 2006, Genetics 174(1): 271--284 Quantitative trait loci for locomotor behavior in Drosophila melanogaster. [FBrf0193517] Haley et al., 2005, Genetics 171(2): 583--595 Impairment of cytotype regulation of P-element activity in Drosophila melanogaster by mutations in the Su(var)205 gene. [FBrf0190726] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Harris et al., 2003, Genetics 165(2): 637--652 A deficiency screen of the major autosomes identifies a gene (matrimony) that is haplo-insufficient for achiasmate segregation in Drosophila oocytes. [FBrf0167662] Firth et al., 2000, Genetics 156(2): 733--748 Identification of genomic regions that interact with a viable allele of the Drosophila protein tyrosine phosphatase corkscrew. [FBrf0129810] Halsell and Kiehart, 1998, Genetics 148(4): 1845--1863 Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis. [FBrf0102325]
Personal communication to FlyBase	BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338] Crowley, 1994.1.18, Letter: TBP-related factor query. Letter: TBP-related factor query. [FBrf0075419]
Letter	Crowley et al., 1993, Nature 361(6412): 557--561 A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila. [FBrf0059122]