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General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include


Deleted Segment
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << kuz << elB << bk2 << pu

Genetic mapping information
Comments on Cytology

Adhr status unknown.

Left limit of break 1 from polytene analysis (FBrf0098381) Right limit of break 1 from polytene analysis (FBrf0053558) Left limit of break 2 from inclusion of elB (FBrf0091422) Right limit of break 2 from polytene analysis (FBrf0098381)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Phenotypic Data
In combination with other aberrations

Df(2L)A400/Df(2L)b88h49 animals are viable as larvae and adults, with no morphological or behavioural abnormalities easily detected during routine culture. Df(2L)A400/Df(2L)b88h49 larvae do not have defects in multiple dendritic neuron morphology. The larvae are normal in their response to external touch with an eyelash or single hair and show a normal response to four different odours in an olfactory taxis assay. The larvae are indistinguishable from wild type in their ability to respond to a hot probe (pain assay). Df(2L)A400/Df(2L)b88h49 third instar larvae move with a decreased number of stops or turns compared to wild-type larvae, resulting in an extended straight or slightly arching contour trail and a total contour trail area nearly twice that of wild-type larvae. Crawling speed during a linear locomotion burst is increased in the mutant larvae compared to wild type. The mutant larvae complete a full contraction wave cycle in only 1.11 seconds compared to 1.94 seconds in wild-type larvae, due to a more rapid progression of the contraction wave from posterior to anterior and a significant decrease in the length of the pause period between contraction waves.

Viable in combination with Df(2L)A400.

NOT in combination with other aberrations

Df(2L)A400/Df(2L)b88h49 mutant adults do not show any defects in sensing food hardness and like the wild-type flies prefer softer food with lower sugar content (0.5mM sucrose, 0.2% agarose) to a hard food with higher sugar content (1mM sucrose, 2% agarose) in a binary choice assay.

Stocks (1)
Notes on Origin
Balancer / Genotype Variants of the Aberration
Separable Components
Other Comments

"irradiation" was stated as tentative. "spontaneous" was stated as tentative.

Reported to not delete Adhr in error; see FBrf0141768 for correction.

Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (10)