FlyBase Aberration Report: Dmel\Df(2R)Su(z)2-1.b8

General Information

Symbol

Df(2R)Su(z)2-1.b8

Species

D. melanogaster

Name

FlyBase ID

FBab0022254

Feature type

chromosomal_deletion

Also Known As

Su(z)2^1.b8

Computed Breakpoints include

49E2;49E7-49F7

Features within 49E2--49F7 Features within 49E1--49F2 (Estimated cytology)

Genomic Maps

JBrowse

Sequence coordinates

2R:12,940,519..12,940,519 (Df(2R)Su(z)2-1.b8:bk1)

(Kahn et al., 2016)

2R:13,122,110..13,122,110 (Df(2R)Su(z)2-1.b8:bk2)

(Kahn et al., 2016)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Su(z)2¹

(Wu and Howe, 1995, Adler et al., 1991, Brunk et al., 1991, Adler et al., 1989)

Mutagen

X ray

(Wu and Howe, 1995)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Wu and Howe, 1995, Brunk et al., 1991)

Breakpoints

[];[]

(Brunk et al., 1991)

49E2-49F1;49E7-49F7

(Wu and Howe, 1995)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)49Dc << bk1 << Mdr49 << Su(z)3 << bk2 << l(2)49Fb

Genetic mapping information

Comments

Breakpoints were reported in Dm3 (R5) coordinates.

(Kahn et al., 2016)

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0082794) Right limit of break 1 from inclusion of Mdr49 (FBrf0082794) Limits of break 2 from polytene analysis (FBrf0082794)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Mdr49

(Wu and Howe, 1995)

Psc

(Soto et al., 1995, Wu and Howe, 1995, Cheng et al., 1994, Brunk et al., 1991, Adler et al., 1989)

Su(z)2

(Emmons et al., 2009, Soto et al., 1995, Wu and Howe, 1995, Cheng et al., 1994, Brunk et al., 1991, Adler et al., 1989)

Partially deleted / disrupted

Su(z)2

(Emmons et al., 2009)

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

AspRS

(Wu and Howe, 1995)

bic

(Wu and Howe, 1995)

Cap-G

(Wu and Howe, 1995)

l(2)49Dc

(Wu and Howe, 1995, Brunk et al., 1991)

l(2)49Fa

(Wu and Howe, 1995)

l(2)49Fb

(Wu and Howe, 1995)

l(2)49Fg

(Wu and Howe, 1995)

l(2)49Fh

(Wu and Howe, 1995)

Orc3

(Wu and Howe, 1995)

seq

(Wu and Howe, 1995)

Su(z)2

(Emmons et al., 2009)

(Wu and Howe, 1995)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (13)

Related Comments

Phenotypic Data

In combination with other aberrations

Df(2R)Su(z)2-1.b8 has no effect on the frequency of X-Y chromosome nondisjunction seen in Df(1)X-1-53B males, but acts as a meiotic drive suppressor, suppressing drive against the X and Y chromosomes in these flies. Suppresses meiotic drive of the Y chromosome in Df(1)X-1 males compared to controls.

(McKee et al., 2000)

Df(2R)Arp1.Fbf1a/Df(2R)Su(z)2-1.b8 embryos have stiff pigmented hairs resembling Fell hairs between the ventral setal belts of the abdominal and thoracic segments.

(Adler et al., 1991)

NOT in combination with other aberrations

Homozygous neuroblast clones in the third larval instar central nervous system appear morphologically normal and have a normal mitotic index.

(Bello et al., 2007)

Somatic mitotic clones of Df(2R)Su(z)2-1.b8 do not induce ovarian defects.

(Narbonne et al., 2004)

Homozygous clones in the wing disc are large in size and rounded in shape and the imaginal disc cells are larger than wild type.

(Beuchle et al., 2001)

Shows no dominant effect on telomeric Position Effect Variegation (PEV) in stocks carrying a variegating w^+mW.hs allele at the telomeres of the second and third chromosomes.

(Cryderman et al., 1999)

Cuticle of zygotic^- mutants resemble those of Psc maternal^- zygotic^- mutants, with defects in head involution, holes in the dorsal epidermis and laterally narrow denticle bands. One wild type paternal copy rescues the maternal^- zygotic^- embryos.

(Soto et al., 1995)

Isolated on the basis of reverting the dominant z¹ eye color suppression associated with Su(z)2¹. In a z¹,w^is/Y background, Df(2R)Su(z)2-1.b8 produces an orange eye colour similar to that found in z¹,w^is/Y;+/+.

(Wu and Howe, 1995)

Mutants show significantly stronger suppression of nos mutant phenotype than do single mutants in Psc or Su(z)2.

(Pelegri and Lehmann, 1994)

Stocks (1)

Bloomington

24467

y¹ w^*; P{neoFRT}42D Df(2R)Su(z)2-1.b8/SM6b, P{eve-lacZ8.0}SB1

Notes on Origin

Discoverer

Revertant.

(Brunk et al., 1991)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

645.13-15asm

645.13-35asm

(Brunk et al., 1991)

Df(2R)Su(z)2-1.b8

(Leatham-Jensen et al., 2019)

Psc-Su(Z)2^1.b8

(Wen et al., 2024)

Psc-Su(z)2

(Beuchle et al., 2001)

Su(z)2-1.b8

(Kahn et al., 2016)

Su(z)2^1.68

(Atchison et al., 2003)

Su(z)2^1.B8

(Bello et al., 2007)

Su(z)2^1.b8

(Wang et al., 2014, Debruhl et al., 2013, Gutiérrez et al., 2012, Ji et al., 2012, Park et al., 2012, Li et al., 2010, Emmons et al., 2009, Narbonne et al., 2004, Beuchle et al., 2001, Mollaaghababa et al., 2001, McKee et al., 2000, Cryderman et al., 1999, Sinclair et al., 1998, Wu and Howe, 1995, Pelegri and Lehmann, 1994, Adler et al., 1991, Brunk et al., 1991)

Name Synonyms

Secondary FlyBase IDs

References (26)

Report Sections

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