Aberration Dmel\Df(2R)or-BR11

General Information
Symbol	Dmel\Df(2R)or-BR11	Species	D. melanogaster
Name		FlyBase ID	FBab0022276
Feature type	chromosomal_deletion
Also Known As	Df(2R)or^BR11, Df(2R)or^BR-11, Df^2Ror-BR11

Computed Breakpoints include	59F6-59F8;60A12-60A16
Deleted segment	59F6--60A16
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Reed, 1992)
Class of aberration (relative to progenitor)	chromosomal_deletion (Reed, 1992, Gunsalus et al., 1995, Wang et al., 1997, Reed and Orr-Weaver, 1997)
Breakpoints	59F6-59F8;60A8-60A16 (Reed, 1992, Gunsalus et al., 1995, Wang et al., 1997, Reed and Orr-Weaver, 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	egl << bk1 << l(2)vsp << mr << bk2 l(2)tid << bk1 << l(2)vsp l(2)60Ac l(2)60Ad l(2)60Ae sei << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0064297) Right limit of break 1 from polytene analysis (FBrf0064297) Left limit of break 2 from inclusion of Phm (FBrf0092591) Right limit of break 2 from polytene analysis (FBrf0064297)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Adk2-60B (Spradling et al., 1999, BDGP Project Members, 1994-1999) Ca-P60A (BDGP Project Members, 1994-1999, Spradling et al., 1999, Krishnan and Basole, 1999.4.2, Sanyal et al., 2005) Chi (Ramain et al., 2000, BDGP Project Members, 1994-1999) Gαs (Wolfgang et al., 2001) ken (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)60Ac (Reed, 1992) l(2)05006 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)vsp (Reed, 1992) Lpt (Chauhan et al., 2012) mr (Reed, 1992) or (Reed, 1992) pd (Reed, 1992) Phm (Spradling et al., 1999, BDGP Project Members, 1994-1999, Kolhekar et al., 1997) sei (Wang et al., 1997) Su(hh)III (Haines and van Den Heuvel, 2000) tsr (Spradling et al., 1999, Chen et al., 2001, BDGP Project Members, 1994-1999, Gunsalus et al., 1995)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	egl (Mach and Lehmann, 1997, Moore, 1997) eIF-5A (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k01015 (BDGP Project Members, 1994-1999) l(2)k06003 (BDGP Project Members, 1994-1999) l(2)k09201 (BDGP Project Members, 1994-1999) snama (Spradling et al., 1999, BDGP Project Members, 1994-1999) spag (Spradling et al., 1999, BDGP Project Members, 1994-1999) Zfrp8 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Inferred to overlap with: Df(2R)bw-WI3128. (Moore, 1997)
NOT in combination with other aberrations	The Df(2R)or-BR11 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	1721 Df(2R)or-BR11, cn¹ bw¹ sp¹/SM6a
Kyoto	106470 Df(2R)or-BR11, cn¹ bw¹ sp¹/SM6a
Notes on Origin
Discoverer	B. Reed.
	on cn bw sp; selected for failure to complement or. (Reed, 1992)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	from genetic analysis extends more distally than Df(2R)G10-7-5. (Reed, 1992)
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	Df(2R)br11 (Haines and van Den Heuvel, 2000) Df(2R)or^BR11 (Wolfgang et al., 2004, Wolfgang et al., 2001, Ramain et al., 2000, Wharton et al., 1999, Wang et al., 1997, Mach and Lehmann, 1997) Df(2R)or^BR-11 (Chen et al., 2001, Reed and Orr-Weaver, 1997, Gunsalus et al., 1995) Df(2R)or-BR-11 (Haines and van Den Heuvel, 2000) Df(2R)or-BR11 (Beumer et al., 2008) Df(2R)or-BR11a (Kirilly et al., 2009) Df^2Ror-BR11 (Hazelett et al., 2012, Chauhan et al., 2012)
Name Synonym
Secondary FlyBase IDs

References ( 25 )

Generate a list of	All references relating to this aberration ( 25 )

List References by type	Research paper ( 20 ) Personal communication to FlyBase ( 2 ) FlyBase analysis ( 1 ) Thesis ( 2 )
Recent research papers ( 2 )
	Chauhan et al., 2012, Development 139(11): 1997--2008 Histone Recognition and Nuclear Receptor Co-Activator Functions of Drosophila Cara Mitad, a Homolog of the N-Terminal Portion of Mammalian MLL2 and MLL3. [FBrf0218263] Hazelett et al., 2012, G3 (Bethesda) 2(7): 789--802 Comparison of Parallel High-Throughput RNA Sequencing Between Knockout of TDP-43 and Its Overexpression Reveals Primarily Nonreciprocal and Nonoverlapping Gene Expression Changes in the Central Nervous System of Drosophila. [FBrf0219102] Show all research papers ...