FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3L)3-52
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General Information
Symbol
Df(3L)3-52
Species
D. melanogaster
Name
FlyBase ID
FBab0022311
Feature type
Computed Breakpoints include
Genomic Maps
Sequence coordinates
3L:24,543,534..24,758,036 (Df(3L)3-52:bk1)
3L:25,798,441..27,136,525 (Df(3L)3-52:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << l(3)80Fb << bk2 << l(3)80Ff

Genetic mapping information
Comments

The 3L:24543534..24758036 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of mRpS5, which Schulze et al. (FBrf0134775) say is not deleted. The right extent corresponds to the right end of scro, which Schulze et al. (FBrf0134775) say is deleted.

The 3L:25798441..27136525 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of CG40178, which Schulze et al. (FBrf0134775) say is deleted. The right extent corresponds to the right end of vtd, which Schulze et al. (FBrf0134775) say is not deleted.

Comments on Cytology

Df(3L)3-52 is a complex rearrangement. The original h52 block is probably present, while the segment spanning from h48 to h50 appears to have been replaced by unknown material (it is possible that some of h50 may still be present). This unknown duplicated material may derive from h52.

Right limit of break 1 from inclusion of l(3)80Fb (FBrf0048227) Right limit of break 2 from non-inclusion of l(3)80Ff (FBrf0048227)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (27)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The Df(3L)3-52 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(3L)3-52 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.

Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Df(3L)3-52
Name Synonyms
Secondary FlyBase IDs
    References (7)