Aberration Dmel\Df(3R)4-75

General Information
Symbol	Dmel\Df(3R)4-75	Species	D. melanogaster
Name		FlyBase ID	FBab0022315
Feature type	chromosomal_deletion

Computed Breakpoints include	[h53--81F6];[>h47]
Deleted segment	h53--h47
Sequence coordinates
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	ethyl methanesulfonate (Marchant and Holm, 1988)
Class of aberration (relative to progenitor)	chromosomal_deletion (Marchant and Holm, 1988)
Breakpoints	[];[] (Marchant and Holm, 1988) [];h58 (Koryakov et al., 2002)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(3)80Fj << bk1 << l(3)81Fa << bk2
Genetic mapping information
Comments
Comments on Cytology
	Df(3R)4-75 appears to be a long pericentric inversion, with one breakpoint located distal to h50 and the other falling within h58. (Koryakov et al., 2002) Left limit of break 1 from non-inclusion of l(3)80Fj (FBrf0048227) Right limit of break 1 from inclusion of l(3)81Fa (FBrf0048227) Left limit of break 2 from inclusion of l(3)81Fa (FBrf0048227)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	l(3)81Fa (Marchant and Holm, 1988) zep (Ostrowski et al., 2002)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	l(3)80Fj (Marchant and Holm, 1988)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(3R)10-65/Df(3R)4-75 animals develop normally until the final stage of embryogenesis. (Hanai, 2001.1.11)
NOT in combination with other aberrations	The Df(3R)4-75 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 1 )
Bloomington	2598 Df(3R)4-75, kni^ri-1 p^p/TM3, Ser¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3R)4-75 (Koryakov et al., 2003)
Name Synonym
Secondary FlyBase IDs

References ( 9 )
Research paper	Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Koryakov et al., 2003, J. Cell Sci. 116(6): 1035--1044 Abnormal tissue-dependent polytenization of a block of chromosome 3 pericentric heterochromatin in Drosophila melanogaster. [FBrf0155869] Koryakov et al., 2002, Genetics 160(2): 509--517 Cytogenetic analysis of the third chromosome heterochromatin of Drosophila melanogaster. [FBrf0144895] Ostrowski et al., 2002, Genetics 161(1): 171--182 Genetic control of cuticle formation during embryonic development of Drosophila melanogaster. [FBrf0149011] Carrera et al., 1998, Proc. Natl. Acad. Sci. USA 95(18): 10779--10784 A modifier screen in the eye reveals control genes for Kruppel activity in the Drosophila embryo. [FBrf0104417] Zhang and Spradling, 1994, Proc. Natl. Acad. Sci. USA 91(9): 3539--3543 Insertional mutagenesis of Drosophila heterochromatin with single P elements. [FBrf0074895] Marchant and Holm, 1988, Genetics 120: 519--532 Genetic analysis of the heterochromatin of chromosome 3 of Drosophila melanogaster. [FBrf0048227]
Personal communication to FlyBase	Hanai, 2001.1.11, FlyBase error report for AE002935 on Wed Jan 10 18:14:20 2001. FlyBase error report for AE002935 on Wed Jan 10 18:14:20 2001. [FBrf0133270]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]