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General Information
Symbol
Df(3L)66C-G28
Species
D. melanogaster
Name
FlyBase ID
FBab0022326
Feature type
Computed Breakpoints include

66B8-66B9;66C9-66C10

Deleted Segment
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints

66B8-66B9;66C9-66C10

Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << E(dpp)66C << bk2 << RpL14

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0086978)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

Fails to complement Df(3L)ZP1.

Df(3L)66C-G28/Df(3L)pbl-X1 lethal (Jeanette Natzle)

NOT in combination with other aberrations

Df(3L)66C-G28 embryos show defects in tracheal cell migration.

The Df(3L)66C-G28 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

Little if any macrophage migration occurs in homozygous embryos, with most macrophages remaining in the anterior region, clustered around the foregut, at stage 13-15.

Heterozygosity for Df(3L)66C-G28 results in a high but variable degree of X chromosome nondisjunction (23.3% and 25.8% in two separate experiments) and fourth chromosome nondisjunction (12.7% and 25.0% in two separate experiments) in In(1)FM7/X ; svspa-pol females. Recombination frequency along the length of the third chromosome does not show significant deviation from normal in females carrying a multiply marked third chromosome and Df(3L)66C-G28.

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

Shows maternal enhancement of dpphr4, dpphr56 and dpphr27, measured as reduction in recovery of doubly heterozygous progeny.

Midgut development of mutant embryos is wild type.

Stocks (2)
Notes on Origin
Discoverer

J. Natzle.

 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

Used in D.melanogaster/D.simulans hybrids to map at least four non-overlapping regions on the D.simulans 3R that have effects on the species difference of cuticular hydrocarbon profile.

Synonyms and Secondary IDs (2)
References (47)