Aberration Dmel\Df(3L)GN50

General Information
Symbol	Dmel\Df(3L)GN50	Species	D. melanogaster
Name		FlyBase ID	FBab0022358
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	Eip63E << bk1 << bk2
Sequence coordinates
Deleted segment	63E2--64B17
Duplicated segment
Computed Breakpoints include	63E2;64B17
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Rawson, 1992, Gepner et al., 1996, Zhimulev et al., 1997.9.29, Deak et al., 1997, Zhimulev et al., 1998)
Breakpoints	63E1-63E2;64B17 (Rawson, 1992, Deak et al., 1997) 63E1-63E2;64B1-64B7 (Gepner et al., 1996) 63E2-63E3;64B17 (Zhimulev et al., 1997.9.29, Zhimulev et al., 1998)
Causes alleles	Eip63E^GN50 (Stowers et al., 2000)
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0098597) Right limit of break 1 from polytene analysis (FBrf0075338) Limits of break 2 from polytene analysis (FBrf0075338)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Awh (Zhimulev et al., 2001) pav (Deak et al., 1997, Szeged Stock Center, 1998-, Collins, 2005) wit (Deak et al., 1997, Szeged Stock Center, 1998-) l(3)S144912 (Deak et al., 1997, Szeged Stock Center, 1998-) l(3)S142916 (Deak et al., 1997, Szeged Stock Center, 1998-) l(3)S137212 (Deak et al., 1997, Szeged Stock Center, 1998-) l(3)S122404 (Deak et al., 1997, Szeged Stock Center, 1998-) l(3)S103616 (Szeged Stock Center, 1998-) l(3)S063813 (Szeged Stock Center, 1998-) l(3)S051022a (Szeged Stock Center, 1998-) l(3)S134012a (Deak et al., 1997) l(3)S127704a (Deak et al., 1997) l(3)S018611b (Deak et al., 1997) l(3)S101206a (Deak et al., 1997) l(3)S104913a (Deak et al., 1997) l(3)S104903a (Deak et al., 1997)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Eip63E (Munroe et al., 1998.5.12) Gad1 (Featherstone et al., 2000) l(3)S024120 (Szeged Stock Center, 1998-) l(3)63Dc (Munroe et al., 1998.5.12) l(3)63Db (Munroe et al., 1998.5.12)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Deficient embryos show a mutant midgut phenotype: gastric caecae do not develop, hypertrophy of anterior midgut. (Bilder and Scott, 1995) Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) The Df(3L)GN50 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Position Effect Variegation Data

Stocks ( 2 )
Bloomington	3687 w¹¹¹⁸; Df(3L)GN50, e^*/TM8, l(3)DTS4¹
Kyoto	107173 w¹¹¹⁸; Df(3L)GN50, e^*/TM8, l(3)DTS4¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	"63E2--3;64B17" was stated as revision. (Zhimulev et al., 1997.9.29) "63E2--3;64B17" was stated as revision. (Zhimulev et al., 1998)
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3L)GN50 (Crest et al., 2007, With et al., 2003)
Name Synonym
Secondary FlyBase IDs

References ( 32 )

Generate a list of	All references relating to this aberration ( 32 )

List References by type	Research paper ( 27 ) Personal communication to FlyBase ( 3 ) FlyBase analysis ( 1 ) Computer file ( 1 )
Recent research papers ( 1 )
	Crest et al., 2007, Genetics 175(2): 567--584 Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644] Show all research papers ...