Aberration Dmel\Df(3L)bab-PG

General Information
Symbol	Dmel\Df(3L)bab-PG	Species	D. melanogaster
Name		FlyBase ID	FBab0022376
Feature type	chromosomal_deletion

Computed Breakpoints include	61D3-61E1;61F5-61F8
Deleted segment	61D3--61F8
Sequence coordinates
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Godt et al., 1993)
Class of aberration (relative to progenitor)	chromosomal_deletion (Godt et al., 1993)
Breakpoints	61D3-61E1;61F5-61F8 (Godt et al., 1993)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << bab1 << bk2
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0065404)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Aplip1 (Horiuchi et al., 2005) bab1 (Godt et al., 1993) Klp61F (Spradling et al., 1999, Wilson et al., 2004) l(3)02640 (Spradling et al., 1999) l(3)S003606 (Wei et al., 2003) msd1 (Wainman et al., 2009) mtacp1 (Spradling et al., 1999) trio (Awasaki et al., 2000, Bateman et al., 2000)
Molecular Data
Completely deleted	trio (Saito et al., 2002)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(3L)Fpa1/Df(3L)bab-PG embryos show severely disrupted patterns of axon wiring, with no longitudinal fascicles being visibly Fas2 staining. (Saito et al., 2002)
NOT in combination with other aberrations	The Df(3L)bab-PG chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	5412 Df(3L)bab-PG, ca¹/TM6B, Tb¹ ca¹
Kyoto	108212 Df(3L)bab-PG, ca¹/TM6B, Tb¹ ca¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	bab^PG (Kopp et al., 2000) Df(3L)bab^PG (Kuzin et al., 2005, Couderc et al., 2002, Bateman et al., 2000, Awasaki et al., 2000, Godt and Laski, 1995, Godt et al., 1993, Saito et al., 2002) Df(3L)bab PG (Wilson et al., 2004) Df(3L)bab-PG (Crest et al., 2007, Wei et al., 2003) Df(3L)Bab-PG (Wainman et al., 2009)
Name Synonym
Secondary FlyBase IDs

References ( 16 )
Research paper	Wainman et al., 2009, Genes Dev. 23(16): 1876--1881 A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes. [FBrf0208631] Crest et al., 2007, Genetics 175(2): 567--584 Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644] Horiuchi et al., 2005, Curr. Biol. 15(23): 2137--2141 APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. [FBrf0190020] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Wilson et al., 2004, J. Cell Sci. 117(21): 4921--4933 Novel nuclear defects in KLP61F-deficient mutants in Drosophila are partially suppressed by loss of Ncd function. [FBrf0180385] Wei et al., 2003, Genome 46(6): 1049--1058 Functional genomic analysis of the 61D-61F region of the third chromosome of Drosophila melanogaster. [FBrf0167686] Couderc et al., 2002, Development 129(10): 2419--2433 The bric a brac locus consists of two paralogous genes encoding BTB/POZ domain proteins and acts as a homeotic and morphogenetic regulator of imaginal development in Drosophila. [FBrf0146992] Saito et al., 2002, Molec. Genet. Genomics 268(4): 446--454 Genetic analyses of essential genes in cytological region 61D1-2 to 61F1-2 of Drosophila melanogaster. [FBrf0155968] Awasaki et al., 2000, Neuron 26(1): 119--131 The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension. [FBrf0126995] Bateman et al., 2000, Neuron 26(1): 93--106 The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryo. [FBrf0127003] Kopp et al., 2000, Nature 408(6812): 553--559 Genetic control and evolution of sexually dimorphic characters in Drosophila. [FBrf0132416] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Godt and Laski, 1995, Development 121(1): 173--187 Mechanisms of cell rearrangement and cell recruitment in Drosophila ovary morphogenesis and the requirement of bric-a-brac. [FBrf0076130] Godt et al., 1993, Development 119(3): 799--812 Pattern formation in the limbs of Drosophila: bric a brac is expressed in both a gradient and a wave-like pattern and is required for specification and proper segmentation of the tarsus. [FBrf0065404]
Supplementary material	Kuzin et al., 2005, Dev. Biol. 277(2): Supplemental materials. [FBrf0183076]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]