A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Aberration Dmel\Df(3R)3450

General Information
SymbolDmel\Df(3R)3450SpeciesD. melanogaster
NameFlyBase IDFBab0022382
Feature typechromosomal_deletion
Also Known AsDf3450
Computed Breakpoints include 98E3;99A6
Deleted segment98E3--99A6
Sequence coordinates
Member of large scale dataset(s)
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Description
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FB2013_03
FB2013_02
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)
Breakpoints
98E3;99A4-99A6
98E3;99A6-99A8
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data bk1 << spg << bk2 << l(3)02521
Genetic mapping information
Comments
hide Comments on Cytology
Limits of break 1 from polytene analysis (FBrf0091073) Left limit of break 2 from polytene analysis (FBrf0099763) Right limit of break 2 from polytene analysis (FBrf0091073)
 
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DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Molecular Data
Completely deleted
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Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
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Complementation Data
Molecular Data
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hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Embryos homozygous for Df(3R)3450, which uncovers Cul-5, have no detectable defects in tracheal morphology.
Df(3R)3450/+ adults show a reduction in notal bristles.
The size of the tracheal lumen is different to wild type in Df(3R)3450 embryos.
The Df(3R)3450 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).
Heterozygosity for Df(3R)3450 results in 0.0% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
Shows no maternal enhancement of dpphr4.
Midgut development of mutant embryos is wild type.
hide Stocks ( 2 )
Bloomington
Kyoto
hide Notes on Origin
Discoverer
S. Hayashi.
 
hide Balancer / Genotype Variants of the Aberration
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hide Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym
Name Synonym
Secondary FlyBase IDs
hide References ( 72 )
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hide Recent research papers ( 8 )
Coen et al., 2012, J. Cell Biol. 198(1): 23--35
Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. [FBrf0218810]
Li et al., 2012, Curr. Biol. 22(22): 2104--2113
Lipid droplets control the maternal histone supply of Drosophila embryos. [FBrf0220040]
Ayyub, 2011, J. Genet. 90(2): 239--249
Cullin-5 and cullin-2 play a role in the development of neuromuscular junction and the female germ line of Drosophila. [FBrf0214802]
Biersmith et al., 2011, PLoS ONE 6(1): e16120
The DOCK Protein Sponge Binds to ELMO and Functions in Drosophila Embryonic CNS Development. [FBrf0212890]
Galy et al., 2011, Dev. Biol. 359(1): 37--46
CYFIP dependent Actin Remodeling controls specific aspects of Drosophila eye morphogenesis. [FBrf0216378]
Ghabrial et al., 2011, PLoS Genet. 7(7): e1002087
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. [FBrf0214368]
Henthorn et al., 2011, Mol. Biol. Cell 22(21): 4038--4046
A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. [FBrf0216511]
Rotkopf et al., 2011, Development 138(13): 2729--2739
The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release. [FBrf0213892]