Aberration Dmel\Df(3R)3450

General Information
Symbol	Dmel\Df(3R)3450	Species	D. melanogaster
Name		FlyBase ID	FBab0022382
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	bk1 << spg << bk2 << l(3)02521
Sequence coordinates
Deleted segment	98E3--99A6
Duplicated segment
Computed Breakpoints include	98E3;99A6
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	γ ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Salzberg et al., 1997, Ahmed et al., 1998)
Breakpoints	98E3;99A4-99A6 (Hayashi et al., 1997) 98E3;99A6-99A8 (Salzberg et al., 1997) 98E3;99A6 (Ahmed et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0091073) Left limit of break 2 from polytene analysis (FBrf0099763) Right limit of break 2 from polytene analysis (FBrf0091073)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Apc (Hayashi et al., 1997) WASp (Ben-Yaacov et al., 2001, Tal et al., 2002) Vha100-1 (Hiesinger et al., 2005) stg (Verheyen et al., 1996, Hayashi et al., 1997, Szeged Stock Center, 1998-) Slbp (Sullivan et al., 2001) l(3)04708 (BDGP Project Members, 1994-1999, Spradling et al., 1999) l(3)s2784 (BDGP Project Members, 1994-1999, Spradling et al., 1999) l(3)S147506 (Szeged Stock Center, 1998-) l(3)S101310 (Szeged Stock Center, 1998-) l(3)S096207 (Szeged Stock Center, 1998-) l(3)S085301 (Szeged Stock Center, 1998-) l(3)S085009 (Szeged Stock Center, 1998-) l(3)S084402 (Szeged Stock Center, 1998-) l(3)S044422 (Szeged Stock Center, 1998-) l(3)S007902 (Szeged Stock Center, 1998-) l(3)3450-C (Ahmed, 2002.7.16) l(3)3450-I (Ahmed, 2002.7.16) l(3)3450-L (Ahmed, 2002.7.16) l(3)3450-P (Ahmed, 2002.7.16) l(3)3450-O (Ahmed, 2002.7.16) l(3)3450-J (Ahmed, 2002.7.16) stoc (Luschnig et al., 2004) l(3)3450-D (Ahmed, 2002.7.16) l(3)3450-K (Ahmed, 2002.7.16) l(3)3450-G (Ahmed, 2002.7.16) l(3)3450-N (Ahmed, 2002.7.16) l(3)3450-A (Ahmed, 2002.7.16) spg (Hayashi et al., 1997) sd-2 (Babcock et al., 2003) l(3)3450-F (Ahmed, 2002.7.16) l(3)3450-H (Ahmed, 2002.7.16) l(3)3450-M (Ahmed, 2002.7.16) l(3)3450-B (Ahmed, 2002.7.16) bek (Kankel et al., 2004) l(3)3450-E (Ahmed, 2002.7.16) Doa (BDGP Project Members, 1994-1999, Hayashi et al., 1997, Spradling et al., 1999, Yun et al., 2000, Morris et al., 2003)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	stg (BDGP Project Members, 1994-1999, Salzberg et al., 1997, Spradling et al., 1999) scrib (Brumby et al., 2004) l(3)02521 (BDGP Project Members, 1994-1999) l(3)s2976 (BDGP Project Members, 1994-1999, Spradling et al., 1999) gim (Myat et al., 2005) fang (Myat et al., 2005) gloin (Myat et al., 2005)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for Df(3R)3450 results in 0.0% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003) Midgut development of mutant embryos is wild type. (Bilder and Scott, 1995) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) The Df(3R)3450 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,w^var}2Lt insertion). (Mason et al., 2004) The size of the tracheal lumen is different to wild type in Df(3R)3450 embryos. (Myat et al., 2005)
Position Effect Variegation Data

Stocks ( 2 )
Bloomington	430 w¹¹¹⁸; Df(3R)3450/TM6B, Tb¹
Kyoto	108901 w¹¹¹⁸; Df(3R)3450/TM6B, Tb¹
Notes on Origin
Discoverer	S. Hayashi.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	DF(3R)3450 (Harris et al., 2003) Df(3R)3450 (Hiesinger et al., 2005)
Name Synonym
Secondary FlyBase IDs

References ( 50 )

Generate a list of	All references relating to this aberration ( 50 )

List References by type	Research paper ( 44 ) Supplementary material ( 1 ) Personal communication to FlyBase ( 2 ) FlyBase analysis ( 1 ) Computer file ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2006 Show research papers ...