Aberration Dmel\Df(3R)ME15

General Information
Symbol	Dmel\Df(3R)ME15	Species	D. melanogaster
Name		FlyBase ID	FBab0022402
Feature type	chromosomal_deletion

Computed Breakpoints include	81F3-81F6;82F5-82F7
Deleted segment	81F3--82F7
Sequence coordinates
Recent Updates
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FB2012_01	References McElwain et al., 2011, PLoS ONE 6(11): e26993
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Carpenter, 1994, Carpenter, 1999)
Breakpoints	81F3-81F6;82F5-82F7 (Carpenter, 1994, Carpenter, 1999)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << l(3)82Fb << l(3)82Fc << bk2 << l(3)82Fj
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0075380)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	hkb (Muller et al., 1999) l(3)82Fa (Carpenter, 1999, Carpenter, 1994) l(3)82Fb (Carpenter, 1999, Carpenter, 1994) l(3)82Fc (Carpenter, 1999, Carpenter, 1994) l(3)82Fd (Carpenter, 1999, Carpenter, 1994) l(3)82Fe (Carpenter, 1999, Carpenter, 1994) tacc (Gergely et al., 2000)
Molecular Data
Completely deleted	lost (Sinsimer et al., 2011)
Genes NOT Deleted / Disrupted
Complementation Data
	hd (Carpenter, 1999, Carpenter, 1994) ins (Green and Piergentili, 2000) kkv (Carpenter, 1999, Ostrowski et al., 2002, Carpenter, 1994) l(3)82Fg (Carpenter, 1999, Carpenter, 1994) l(3)82Fi (Carpenter, 1999, Carpenter, 1994) l(3)82Fj (Carpenter, 1999, Carpenter, 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for Df(3R)ME15 results in 0.6% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003) Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22. (Burnette et al., 1999)
Stocks ( 1 )
Kyoto	106711 Df(YS)bb^-; Df(3R)ME15, mwh¹ red¹ e⁴/MKRS
Notes on Origin
Discoverer	A.T.C. Carpenter. (Carpenter, 1994)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(3R)ME15 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but the eye colour phenotype in the presence of Df(3R)ME15 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. (Mason et al., 2004) kkv has been found to fail to complement Df(3R)3-4 and to complement Df(3R)ME15, placing it in 82F5-82F11, contradicting earlier work that placed kkv between 83C1 and 84B2 (FBrf0041709). (Ostrowski et al., 2002)
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df81F3-82F5,7 (Green and Piergentili, 2000) DF(3R)ME15 (Harris et al., 2003) Df(3R)ME15 (Tang et al., 2006, Sinsimer et al., 2011, McElwain et al., 2011)
Name Synonym
Secondary FlyBase IDs

References ( 23 )

Generate a list of	All references relating to this aberration ( 23 )

List References by type	Research paper ( 21 ) FlyBase analysis ( 1 ) Stock list ( 1 )
Recent research papers ( 2 )
	McElwain et al., 2011, PLoS ONE 6(11): e26993 A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration. [FBrf0216663] Sinsimer et al., 2011, Development 138(16): 3431--3440 A late phase of germ plasm accumulation during Drosophila oogenesis requires Lost and Rumpelstiltskin. [FBrf0214542] Show all research papers ...