|Computed Breakpoints include|
|Member of large scale dataset(s)|
What does this section display?
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data|
|Genetic mapping information|
|Comments on Cytology|
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Completely deleted / disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
When males with Dp(1;1)Co are crossed with T(1;2)scS2 females, and somatic clones are induced (in the wing disc) with a FRT site at 18A, clones with cells containing 4 copies of dm (2 endogenous and 2 from the tandem duplication in Dp(1;1)Co) and heterozygous for RpL19 (due to missing one copy of RpL19 on Ts(1Lt;2Lt)scS2). These clones are unable to out-compete surrounding cells and are eliminated.
|NOT in combination with other aberrations|
Ts(1Lt;2Lt)scS2/+ animals survive to adulthood. Ts(1Lt;2Lt)scS2/+ clones in a wild-type background in the wing disc are readily observed by 24 hours after clone induction, but after 24 hours the Ts(1Lt;2Lt)scS2/+ clones are smaller than their Ts(1Rt;2Rt)scS2 twin clones and their frequency decreases. At 48 hours after clone induction Ts(1Lt;2Lt)scS2/+ clones are not observed. There is evidence for apoptosis associated with the Ts(1Lt;2Lt)scS2/+ clones.
|Stocks ( 0 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
|Synonyms & Secondary IDs ( 3 )|
|Secondary FlyBase IDs|
|References ( 4 )|