Aberration Dmel\Df(2L)N6

General Information
Symbol	Dmel\Df(2L)N6	Species	D. melanogaster
Name		FlyBase ID	FBab0023572
Feature type	chromosomal_deletion

Computed Breakpoints include	23A6;23B1
Deleted segment	23A6--23B1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	Syt1^T77 (Littleton et al., 1995)
Mutagen	Delta2-3 (Littleton and Bellen, 1994)
Class of aberration (relative to progenitor)	chromosomal_deletion (Littleton and Bellen, 1994, Hartenstein et al., 1997)
Breakpoints	23A6;23B1 (Littleton and Bellen, 1994, Hartenstein et al., 1997)
Causes alleles	Syt1^N6 (Littleton and Bellen, 1994, Littleton et al., 1995)
Carries alleles
Transposon Insertions	P{5'lacW}Syt1^N6 (Littleton et al., 1993)
Formalized genetic data	bk1 << aph-1 << l(2)23AB2 << bk2 << syt
Genetic mapping information
Comments
Comments on Cytology
	Ref: Littleton et al., 1993, Cell 74(6): 1125--1134. 30kb deletion. (Littleton and Bellen, 1994) All limits from polytene analysis (FBrf0076536)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	aph-1 (Littleton and Bellen, 1994) colt (Hartenstein et al., 1997) l(2)23AB2 (Littleton and Bellen, 1994) l(2)23AB4 (Littleton and Bellen, 1994) Syt1 (Stefancsik, 2002.5.22, Littleton and Bellen, 1994, Littleton et al., 1995) Taf10b (Hernandez-Hernandez and Ferrus, 2001)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Cy (Stefancsik, 2002.5.22) Hrs (Littleton and Bellen, 1994) Pgk (Littleton and Bellen, 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 2 )
Bloomington	3910 y¹ w^*; Df(2L)N6, P{lacW}B8-2-30, Syt1^N6/CyO
Kyoto	107263 y¹ w^*; Df(2L)N6, P{lacW}B8-2-30, Syt1^N6/CyO
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(2L)N6 (Wang et al., 2004, Popkova et al., 2012)
Name Synonym
Secondary FlyBase IDs

References ( 11 )
Research paper	Popkova et al., 2012, PLoS Genet. 8(12): e1003159 Polycomb controls gliogenesis by regulating the transient expression of the gcm/glide fate determinant. [FBrf0220515] Wang et al., 2004, J. Neurosci. 24(19): 4518--4529 A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function. [FBrf0174860] Hu and Fortini, 2003, J. Cell Biol. 161(4): 685--690 Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex. [FBrf0160621] Presgraves, 2003, Genetics 163(3): 955--972 A fine-scale genetic analysis of hybrid incompatibilities in Drosophila. [FBrf0158988] Hernandez-Hernandez and Ferrus, 2001, Mol. Cell. Biol. 21(2): 614--623 Prodos is a conserved transcriptional regulator that interacts with dTAF(II)16 in Drosophila melanogaster. [FBrf0132410] Hartenstein et al., 1997, Genetics 147(4): 1755--1768 The congested-like tracheae gene of Drosophila melanogaster encodes a member of the mitochondrial carrier family required for gas-filling of the tracheal system and expansion of the wings after eclosion. [FBrf0099765] Littleton et al., 1995, J. Neurochem. 65(1): 32--40 Immunocytochemical analysis of axonal outgrowth in synaptotagmin mutations. [FBrf0083593] Littleton and Bellen, 1994, Genetics 138(1): 111--123 Genetic and phenotypic analysis of thirteen essential genes in cytological interval 22F1-2; 23B1-2 reveals novel genes required for neural development in Drosophila. [FBrf0076536] Littleton et al., 1993, Cell 74(6): 1125--1134 Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca²⁺-activated neurotransmitter release. [FBrf0064585]
Personal communication to FlyBase	Stefancsik, 2002.5.22, l(2)k05909. l(2)k05909. [FBrf0149625]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]