Aberration Dmel\Df(3L)Aprt-32

General Information
Symbol	Dmel\Df(3L)Aprt-32	Species	D. melanogaster
Name		FlyBase ID	FBab0023708
Feature type	chromosomal_deletion
Also Known As	Df(3L)Aprt32, Df(3L)Aprt 32

Computed Breakpoints include	62B1;62E3
Deleted segment	62B1--62E3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Wang et al., 1994)
Class of aberration (relative to progenitor)	chromosomal_deletion (Wang et al., 1994, Zhimulev et al., 1997.9.29, Zhimulev et al., 1998, Keegan et al., 2001)
Breakpoints	62A2-62B1;62E6-62F1 (Wang et al., 1994) 62B1-62B2;62E3 (Zhimulev et al., 1997.9.29, Zhimulev et al., 1998) [];62F1--2 (Keegan et al., 2001)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << l(3)62Bc << l(3)62Da << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0098597) Right limit of break 1 from polytene analysis (FBrf0076966) Limits of break 2 from polytene analysis (FBrf0098597)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Aprt (Wang et al., 1994) dlt (Wang et al., 1994) dre4 (Wang et al., 1994) ecd (Wang et al., 1994) l(3)62Bb (Wang et al., 1994) l(3)62Bc (Wang et al., 1994) l(3)62Bh (Wang et al., 1994) l(3)62Bi (Wang et al., 1994) l(3)62Bj (Wang et al., 1994) l(3)62Da (Wang et al., 1994) msn (Spradling et al., 1999, Keegan et al., 2001) mu2 (Wang et al., 1994) R (Wang et al., 1994) sls (Spradling et al., 1999, Wang et al., 1994) Tmhs (Wang et al., 1994, Spradling et al., 1999) α-Spec (Wang et al., 1994, Huelsmeier et al., 2007)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	l(3)02104 (Spradling et al., 1999) l(3)neo8 (Spradling et al., 1999) S(CycE^JP)59S18 (Brumby et al., 2004)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Lethal in combination with Df(3L)BSC116. Inferred to overlap with: Df(3L)BSC116. (Andrade and Cook, 2005.7.22)
NOT in combination with other aberrations	The salivary gland distal tip does not initiate turning and migration in embryos homozygous for Df(3L)Aprt-32 by stage 14. (Jattani et al., 2009)
Stocks ( 2 )
Bloomington	5411 Df(3L)Aprt-32/TM6
Kyoto	108211 Df(3L)Aprt-32/TM6
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	"62B1--2;62E3" was stated as revision. (Zhimulev et al., 1997.9.29, Zhimulev et al., 1998)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(3L)AG32 (Keegan et al., 2001) Df(3L)aprt (Huelsmeier et al., 2007) Df(3L)Aprt32 (Claycomb et al., 2004, Pielage et al., 2003, Spradling et al., 1999, Wang et al., 1994, Huelsmeier et al., 2007) Df(3L)Aprt 32 (Zhimulev et al., 1998, Zhimulev et al., 1997.9.29) Df(3L)Aprt-32 (Goodliffe et al., 2007) Df(3L)ApRT32 (Jattani et al., 2009)
Name Synonym
Secondary FlyBase IDs

References ( 16 )
Research paper	Jattani et al., 2009, Dev. Dyn. 238(4): 853--863 Deficiency screen identifies a novel role for beta 2 tubulin in salivary gland and myoblast migration in the Drosophila embryo. [FBrf0207774] Goodliffe et al., 2007, BMC Mol. Biol. 8: 40 Coordinated regulation of Myc trans-activation targets by polycomb and the trithorax group protein Ash1. [FBrf0201535] Huelsmeier et al., 2007, Development 134(4): 713--722 Distinct functions of α-Spectrin and β-Spectrin during axonal pathfinding. [FBrf0194635] Brumby et al., 2004, Genetics 168(1): 227--251 A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila. [FBrf0180291] Claycomb et al., 2004, Dev. Cell 6(1): 145--155 Gene amplification as a developmental strategy: isolation of two developmental amplicons in Drosophila. [FBrf0167486] Yan and Macdonald, 2004, Genetics 168(3): 1433--1442 Genetic interactions of Drosophila melanogaster arrest reveal roles for translational repressor Bruno in accumulation of Gurken and activity of Delta. [FBrf0180283] Pielage et al., 2003, Dev. Cell 5(6): 841--851 The Drosophila cell survival gene discs lost encodes a cytoplasmic Codanin-1-like protein, not a homolog of tight junction PDZ protein Patj. [FBrf0167484] Smulders-Srinivasan and Lin, 2003, Genetics 165(4): 1971--1991 Screens for piwi suppressors in Drosophila identify dosage-dependent regulators of germline stem cell division. [FBrf0167655] Fanara et al., 2002, Genetics 162(3): 1321--1328 Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior. [FBrf0155481] Keegan et al., 2001, Genet. Res. (Camb.) 77(1): 27--39 The 62E early-late puff of Drosophila contains D-spinophilin, an ecdysone-inducible PDZ-domain protein dynamically expressed during metamorphosis. [FBrf0135784] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Zhimulev et al., 1998, D. I. S. 81: 209 New cytological data on some chromosome rearrangements in D. melanogaster. [FBrf0105469] Wang et al., 1994, Mol. Gen. Genet. 245(5): 598--607 Mapping a mutator, mu2, which increases the frequency of terminal deletions in Drosophila melanogaster. [FBrf0076966]
Personal communication to FlyBase	Andrade and Cook, 2005.7.22, Isolation and characterization of Df(3L)BSC116. Isolation and characterization of Df(3L)BSC116. [FBrf0188658] Zhimulev et al., 1997.9.29, Stocks - aberrations. Stocks - aberrations. [FBrf0098597]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]