FlyBase Aberration Report: Dmel\Df(3L)Aprt-32

General Information

Symbol

Df(3L)Aprt-32

Species

D. melanogaster

Name

FlyBase ID

FBab0023708

Feature type

chromosomal_deletion

Also Known As

Df(3L)Aprt32

Computed Breakpoints include

62B1;62E3

Features within 62B1--62E3

Genomic Maps

JBrowse

Sequence coordinates

3L:1,668,654..1,795,328 (Df(3L)Aprt-32:bk1)

(Cook, 2016.2.8)

3L:2,554,847..2,587,456 (Df(3L)Aprt-32:bk2)

(Cook, 2016.2.8)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

gamma ray

(Wang et al., 1994)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Keegan et al., 2001, Zhimulev et al., 1998, Zhimulev et al., 1997.9.29, Wang et al., 1994)

Breakpoints

62A2-62B1;62E6-62F1

(Wang et al., 1994)

62B1-62B2;62E3

(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)

[];62F1--2

(Keegan et al., 2001)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 << l(3)62Bc << l(3)62Da << bk2

Genetic mapping information

Comments

The 3L:1668654..1795328 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of RpL23A, because Df(3L)Aprt-1 heterozygotes to not show the Minute phenotypes associated with deletion of this haploinsufficient gene. The right extent corresponds to the right ends of dlt and alpha-Spec, which published results say are deleted.

(Cook, 2016.2.8)

The 3L:2554847..2587456 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of msn, which published results say is deleted. The right extent corresponds to the left end of RpL8, because Df(3L)Aprt-1 heterozygotes do not show the Minute phenotypes associated with deletion of this haploinsufficient gene.

(Cook, 2016.2.8)

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0098597) Right limit of break 1 from polytene analysis (FBrf0076966) Limits of break 2 from polytene analysis (FBrf0098597)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Aprt

(Wang et al., 1994)

CG2021

(Spradling et al., 1999, Wang et al., 1994)

dlt

(Wang et al., 1994)

dre4

(Wang et al., 1994)

ecd

(Wang et al., 1994)

l(3)62Bb

(Wang et al., 1994)

l(3)62Bc

(Wang et al., 1994)

l(3)62Bh

(Wang et al., 1994)

l(3)62Bi

(Wang et al., 1994)

l(3)62Bj

(Wang et al., 1994)

l(3)62Da

(Wang et al., 1994)

msn

(Kiely and Gilbert-Ross, 2021, Keegan et al., 2001, Spradling et al., 1999)

mu2

(Wang et al., 1994)

Rap1

(Wang et al., 1994)

sls

(Spradling et al., 1999, Wang et al., 1994)

α-Spec

(Hülsmeier et al., 2007, Wang et al., 1994)

Partially deleted / disrupted

Molecular Data

Completely deleted

mRpL23

(Marygold et al., 2007)

mRpL46

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

l(3)02104

(Spradling et al., 1999)

l(3)neo8

(Spradling et al., 1999)

S(CycE^JP)59S18

(Brumby et al., 2004)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (123)

Related Comments

Phenotypic Data

In combination with other aberrations

Lethal in combination with Df(3L)BSC116. Inferred to overlap with: Df(3L)BSC116.

(Andrade and Cook, 2005.7.22)

NOT in combination with other aberrations

The salivary gland distal tip does not initiate turning and migration in embryos homozygous for Df(3L)Aprt-32 by stage 14.

(Jattani et al., 2009)

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

Stocks (2)

5411

108211

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"62B1--2;62E3" was stated as revision.

(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Df(3L)AG32

(Keegan et al., 2001)

Df(3L)ApRT32

(Jattani et al., 2009)

Df(3L)Aprt 32

(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)

Df(3L)Aprt-32

(McPherson et al., 2023, Pan et al., 2022, Kiely and Gilbert-Ross, 2021, Hadjieconomou et al., 2020, Li et al., 2020, Sawyer et al., 2020, Goodliffe et al., 2007)

Df(3L)Aprt32

(Hülsmeier et al., 2007, Claycomb et al., 2004, Pielage et al., 2003, Spradling et al., 1999, Wang et al., 1994)

Df(3L)aprt

(Hülsmeier et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (24)

Report Sections

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